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Biological Responses to Nanoscale Particles: Molecular and Cellular Aspects and Methodological Approaches, Gehr Peter, Zellner Reinhard


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Автор: Gehr Peter, Zellner Reinhard
Название:  Biological Responses to Nanoscale Particles: Molecular and Cellular Aspects and Methodological Approaches
ISBN: 9783030124632
Издательство: Springer
Классификация:




ISBN-10: 3030124630
Обложка/Формат: Paperback
Страницы: 344
Вес: 0.51 кг.
Дата издания: 29.10.2020
Язык: English
Размер: 23.39 x 15.60 x 1.93 cm
Ссылка на Издательство: Link
Поставляется из: Германии
Описание:

1. Manufacturing (methods) and characterization (with respect to

size, shape, surface properties, coatings, charge etc.) of materials

1.1 Metal and oxide nanoparticles (Au, Ag, ZnO, SPIOs, Silica.....)

(M. Epple et al., C. Graf, E. Rьhl, St. Barcikowski)

1.2 Quantum dots and quantum rods

(A. Eychmьller, H. Weller et al. )

1.3 Carbon nano tubes

(M. Kappes, KIT)

1.4 Polymer particles

(K. Landfester et al.)

1.5 Surface functionalized and complex ligand shell particles

(W. Parak et al.)

1.6 Stability of NP emulsions and particle agglomeration

(M. Maskos, M. Epple, H. Hoffmann (EPFL Lausanne))

2 Interactions of nanoparticles with proteins

2.1 Formation, growth dynamics and stabilities of protein coronae

(G. U. Nienhaus et al.)

2.2 Protein selectivity in protein adsorption

(R. Tenzer, R. Stauber)

2.3 The biological significance of protein coronae

(Iseult Lynch (U. Birmingham) et al.)


3 Membrane transfer mechanisms, cellular uptake and intracellular trafficking of nanoparticles

3.1 Transport across air-liquid interfaces

(C.M. Lehr, Helmholtz-Institut fьr Pharma. Forsch., Saarbrьcken, H.J. Galla, Mьnster)

3.2 Cellular uptake mechanisms (including adhesive interactions and

3D Fluorescence Microscopy)

(B. Rothen et al., G.U. Nienhaus)

3.3 The role of particle surface charge and membrane elasticity in membrane

transfer

(A. Janshoff et al. (Gцttingen), A. Wixforth (Augsburg), A. Reller (Ulm))

3.4 Localization in cells and sub-cellular compartments using state-of-

the-art imaging techniques incl. super-resolution microscopy

(E. Rьhl, C. Graf.....)

4 Cellular responses and health effects

4.1 Cellular defense, ROS formation and cytotoxicity

(V. Stone, Heriot-Watt Edinburgh)

4.2 The inflammasome

(K. Landfester, V. Mailдnder)

4.3 Interactions with lung cells, fate and translocations

(B. Rothen et al. Fribourg (CH))

4.4 Interactions with skin cells and skin

(J. Lademann et al.)

4.5 Fate and translocations in GI track

(A. Frey (Borstel), P. Nielsen, Hamburg)

4.5 Nanomedicine



Heme Biology: Heme Acts As A Versatile Signaling Molecule Regulating Diverse Biological Processes (Second Edition)

Автор: Zhang Li
Название: Heme Biology: Heme Acts As A Versatile Signaling Molecule Regulating Diverse Biological Processes (Second Edition)
ISBN: 9811211280 ISBN-13(EAN): 9789811211287
Издательство: World Scientific Publishing
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Цена: 15840.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction of the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the versatile roles of heme in controlling diverse molecular and cellular processes germane to human life and disease processes. In the second edition, a new chapter is devoted to describe findings about heme uptake, transport, and trafficking of heme synthesis intermediates in mammals. Additionally, a chapter about the newly discovered roles of elevated heme biosynthesis and uptake in lung tumorigenesis is included.

Heme Biology is unified and logical in presentation. It is well suited for students and professionals in life sciences who wish to know about the fascinating biology of heme and its usefulness in health and diseases. It may also be used as a reference book for advanced readers and researchers who are interested in heme biology. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary information for researchers to have an in-depth molecular understanding of heme biology and further their studies in this fascinating realm.

Cellular and Molecular Bases of Biological Clocks

Автор: Leland N. Jr. Edmunds
Название: Cellular and Molecular Bases of Biological Clocks
ISBN: 1461283299 ISBN-13(EAN): 9781461283294
Издательство: Springer
Рейтинг:
Цена: 14673.00 р.
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Описание: The six chapters of this work include a brief introduction to circadian (24-hour) rhythms, a survey of circadian organization at the cellular level, and a description of the important microorganisms that have served as experimental models for biochemical analysis.

Imaging Cellular and Molecular Biological Functions

Автор: Spencer L. Shorte; Friedrich Frischknecht
Название: Imaging Cellular and Molecular Biological Functions
ISBN: 3540713301 ISBN-13(EAN): 9783540713302
Издательство: Springer
Рейтинг:
Цена: 32652.00 р.
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Описание: Offers a comprehensive selection of essays that covers various aspects of modern imaging, from its application and up-scaling to its development. This book includes chapter content that ranges from the basics to the complex overview of method and protocols. It features all-colour-plate chapters, licensed software and a website forum.

Biological Responses to Nanoscale Particles

Автор: Peter Gehr
Название: Biological Responses to Nanoscale Particles
ISBN: 3030124606 ISBN-13(EAN): 9783030124601
Издательство: Springer
Рейтинг:
Цена: 12577.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In this book the recent progress accumulated in studies of the interaction of engineered nanoparticles with cells and cellular constituents is presented. The focus is on manufacturing and characterization of nanosized materials, their interactions with biological molecules such as proteins, the mechanisms of transport across biological membranes as well as their effects on biological functions. Fundamental molecular and cellular aspects are in the foreground of the book.

A further particularity is the interdisciplinary approach, including fields such as preparatory and analytical chemistry, biophysics and the physics of colloids, advanced microscopy and spectroscopy for in-situ detection of nanoparticles, cellular toxicology and nanomedicine. Nanoscale particles are known to exhibit novel and unprecedented properties that make them different from their corresponding bulk materials. As our ability to control these properties is further advanced, a huge potential to create materials with novel properties and applications emerges.

Although the technological and economic benefits of nanomaterials are indisputable, concerns have also been raised that nanoscale structuring of materials might also induce negative health effects. Unfortunately, such negative health effects cannot be deduced from the known toxicity of the corresponding macroscopic material. As a result, there is a major gap in the knowledge necessary for assessing their risk to human health.


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