Reviews of Physiology, Biochemistry and Pharmacology, Vol. 172, Nilius Bernd, De Tombe Pieter, Gudermann Thomas
Автор: F. Wehner; H. Olsen; H. Tinel; E. Kinne-Safran; R. Название: Reviews of Physiology, Biochemistry and Pharmacology ISBN: 366231228X ISBN-13(EAN): 9783662312285 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
Описание: This book identifies and elaborates the most recent and compelling strategies for antibiotic drug discovery with a primary focus on new targets, mechanisms and molecular entities.
Описание: This book includes all of the theory as well as the practical side of pharmaceutical biochemistry, presented in a simple, yet comprehensive, way. It includes chapters on topics such as biomolecules, biogeneratics, energy rich compounds, biological oxidation, the catalytic role of enzymes, the importance of enzyme inhibitors in the design of new drugs, and therapeutic and diagnostic applications of enzymes.
Описание: Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
Автор: Bernd Nilius; Susan G. Amara; Thomas Gudermann; Re Название: Reviews of Physiology, Biochemistry and Pharmacology, Vol. 165 ISBN: 3319345893 ISBN-13(EAN): 9783319345895 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a current and comprehensive view on key topics in the field. Coverage includes chemosensory TRP channels in the respiratory tract; the cardiomyocyte cell cycle in hypertrophy, tissue homeostasis, and regeneration; and the exocrine pancreas.
Автор: Bernd Nilius; Pieter de Tombe; Thomas Gudermann; R Название: Reviews of Physiology, Biochemistry and Pharmacology Vol. 174 ISBN: 3030087824 ISBN-13(EAN): 9783030087821 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
Автор: Nilius Bernd, De Tombe Pieter, Gudermann Thomas Название: Reviews of Physiology, Biochemistry and Pharmacology Vol. 170 ISBN: 3319810510 ISBN-13(EAN): 9783319810515 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
Автор: Bernd Nilius; Susan G. Amara; Thomas Gudermann; Re Название: Reviews of Physiology, Biochemistry and Pharmacology, Vol. 163 ISBN: 3642444849 ISBN-13(EAN): 9783642444845 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Written by leading experts, this volume offers high-quality, in-depth reviews in the fields cardiovacular system, respiratory tract, channel physiology and TRPs
Автор: Nilius Bernd, De Tombe Pieter, Gudermann Thomas Название: Reviews of Physiology, Biochemistry and Pharmacology, Vol. 171 ISBN: 3319829165 ISBN-13(EAN): 9783319829166 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
Описание: This book details chiroptical spectroscopic methods: electronic circular dichroism (ECD), optical rotatory dispersion (ORD), vibrational circular dichroism (VCD), and vibrational Raman optical activity (VROA). For each technique, the text presents experimental methods for measurements and theoretical methods for analyzing the experimental data. It also includes a set of experiments that can be adopted for undergraduate teaching laboratories. Each chapter is written in an easy-to-follow format for novice readers, with necessary theoretical formalism in appendices for advanced readers.
Автор: Sandeep Kumar Название: Developability of Biotherapeutics: Computational Approaches ISBN: 1482246139 ISBN-13(EAN): 9781482246131 Издательство: Taylor&Francis Рейтинг: Цена: 24499.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Biopharmaceuticals are emerging as frontline medicines to combat several life-threatening and chronic diseases. However, such medicines are expensive to develop and produce on a commercial scale, contributing to rising healthcare costs. Developability of Biotherapeutics: Computational Approaches describes applications of computational and molecular modeling techniques that improve the overall process of discovery and development by removing empiricism.
The concept of developability involves making rational choices at the pre-clinical stages of biopharmaceutical drug development that could positively impact clinical outcomes. The book also addresses a general lack of awareness of the many different contributions that computation can make to biopharmaceutical drug development.
This informative and practical reference is a valuable resource for professionals engaged in industrial research and development, scientists working with regulatory agencies, and pharmacy, medicine, and life science students and educators. It focuses primarily on the developability of monoclonal antibody candidates, but the principles described can also be extended to other modalities such as recombinant proteins, fusion proteins, antibody drug conjugates and vaccines.
The book is organized into two sections. The first discusses principles and applications of computational approaches toward discovering and developing biopharmaceutical drugs. The second presents best practices in developability assessments of early-stage biopharmaceutical drug candidates.
In addition to raising awareness of the promise of computational research, this book also discusses solutions required to improve the success rate of translating biologic drug candidates into products available in the clinic. As such, it is a rich source of information on current principles and practices as well as a starting point for finding innovative applications of computation towards biopharmaceutical drug development.
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