Pancreatic Islet Isolation: From the Mouse to the Clinic, Ramнrez-Domнnguez Miriam
Автор: Ram?rez-Dom?nguez Название: Pancreatic Islet Isolation ISBN: 3319398229 ISBN-13(EAN): 9783319398228 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevant species (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.
Автор: A. Hardikar Anandwardhan Название: Pancreatic Islet Biology ISBN: 3319832646 ISBN-13(EAN): 9783319832647 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.
Автор: A. Hardikar Название: Pancreatic Islet Biology ISBN: 331945305X ISBN-13(EAN): 9783319453057 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.
Автор: August Epple; Jack E. Brinn Название: The Comparative Physiology of the Pancreatic Islets ISBN: 3642831842 ISBN-13(EAN): 9783642831843 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This approach required an arbitrary reduction of the num- ber of references, and we therefore join the chorus of recent authors who beg their colleagues for understanding if some of their publications do not appear in the bibliography.
Автор: Joseph R. Pisegna Название: Management of Pancreatic Neuroendocrine Tumors ISBN: 1493946633 ISBN-13(EAN): 9781493946631 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides the reader with a multidisciplinary approach that is state of the art and reflects input from the European Neuroendocrine Tumor Society and the North American Neuroendocrine Tumor Society.
Автор: Porter Clark Название: Pancreatic Surgery: Clinical Principles and Practice ISBN: 1632416018 ISBN-13(EAN): 9781632416018 Издательство: Неизвестно Рейтинг: Цена: 24140.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Seino Название: Pancreatic Beta Cell in Health and Disease ISBN: 4431998373 ISBN-13(EAN): 9784431998372 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This book provides a comprehensive review of the beta cell in health and disease.
Автор: Illani Atwater; Eduardo Rojas; Bernat Soria Название: Biophysics of the Pancreatic ?-Cell ISBN: 1468453165 ISBN-13(EAN): 9781468453164 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The International Workshop on Biophysics of the Pancreatic a-Cell held in Alicante (Spain) on Sep- tember 30 - October 1, 1985, has now given us the opportunity to share experiences with these new techniques applied to the a-cell.
Автор: Johnson Название: Pancreatic Disease.2004 ISBN: 1852337117 ISBN-13(EAN): 9781852337117 Издательство: Springer Рейтинг: Цена: 29209.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Pancreatic Disease: Basic Science and Clinical Management summarises the state of the art in basic science and clinical management of pancreatic disease. This book provides a clear and up-to-date review of the advancing areas in clinical pancreatology and clinical research related to the pancreas. Written by leading experts in the field, this comprehensive review directs the interested reader towards important and current published source material. Covering all aspects of pancreatic disease, contributions are included from pancreatic surgeons and medical pancreatologists on pancreatic cancer, acute pancreatitis and chronic pancreatitis. Special features include a systematic review of the evidence for the use of gemcitabine in pancreatic cancer prepared for the National Institute of Clinical Excellence (NICE), the UK body charged with evaluating new drug treatment. Gemcitabine has FDA approval. There are several contributions dealing with the management of pancreatic neuroendocrine tumours. This book will be useful to gastroenterologists, internists and surgeons, and specialist clinicians with an interest in pancreatic disease. Trainees in medical and surgical pancreatology will find it a companion to supplement standard textbooks.
Автор: Sterling Noel Название: Pancreatic Pathology ISBN: 1632416069 ISBN-13(EAN): 9781632416063 Издательство: Неизвестно Рейтинг: Цена: 22530.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The pancreas is an organ, which has both an endocrine and an exocrine function. It secretes several important hormones such as insulin, glucagon, pancreatic polypeptide and somatostatin. Also, it is responsible for the secretion of pancreatic juice, which contains digestive enzymes and bicarbonates for the break down of lipids, carbohydrates, proteins and the neutralization of the acid. A perforation of the pancreas may potentially lead to pancreatic self-digestion and damage to organs within the abdomen. Some of the pathological conditions of the pancreas include pancreatic cancer, pancreatitis, diabetes mellitus, etc. The surgical removal of the pancreas or part of it is known as pancreatectomy. It can be of several types such as distal pancreatectomy, pancreaticoduodenectomy, total pancreatectomy and segmental pancreatectomy. These procedures are performed for the management of pancreatic cancer, tumor and pancreatitis. This book covers in detail some existing theories and innovative concepts revolving around pancreatic pathology. From theories to research to practical applications, case studies related to all contemporary topics of relevance to this field have been included in this book. It will help the readers in keeping pace with the rapid changes in this field.
Описание: Surgery remains a challenge for young learners. Perhaps the most difficult of all surgeries are those done on the liver, biliary tree and pancreas. These organs are difficult to expose, difficult to operate and the patients are often difficult to recover. There are significant consequences for any missteps on what is a narrow pathway to a successful outcome. The skills needed to master surgery on these organs are hard to acquire. The volume of information presented to students is enormous and complex to parse. HPB textbooks contain a large amount of information from various authors but are often poorly coordinated. Surgical manuals contain significant anatomic details and descriptions but have difficulty transferring key concepts. Experienced surgeons are often oblivious to their skills and communicate poorly to their students regarding the things they do or understand that make them wise. This book tries to capture this wisdom. The topics in this book are most applicable to hepatobiliary and pancreatic surgeons but really extend to all general surgeons. Anyone who operates in the abdomen must have a basic understanding of these dominant organs; general surgery trainees and staff are an additional focus of this book. The skills needed for a modern surgeon to succeed are much broader than the scalpel tip. Section I, "HPB Surgical Craft", imparts important lessons on the laws of human interactions and cognitive aspects of surgery. Sections on the anatomy and operations on the liver, pancreas and bile ducts are presented. The expanded "Gallbladder Expert" section and pancreatitis chapters are of particular importance to general surgery residents. This book has been written in a readable and entertaining style, with many fun historical and contemporary quotes dotted throughout. The Wise Scalpel is an attempt to impart knowledge and understanding to students and practicing surgeons at all levels. The book focuses on tips, traps and underlying truths about the diseases of these organs and their surgical treatment. While this book will not supplant the struggle needed to move from novice to expert surgeon, hopefully it will quicken the process and help avoid some of the dangers and frustrations along the way.
Автор: Joseph R. Pisegna Название: Management of Pancreatic Neuroendocrine Tumors ISBN: 1493917978 ISBN-13(EAN): 9781493917976 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides the reader with a multidisciplinary approach that is state of the art and reflects input from the European Neuroendocrine Tumor Society and the North American Neuroendocrine Tumor Society.
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