Antiepileptic Drug Discovery: Novel Approaches, Talevi Alan, Rocha Luisa

Автор: Cafer Jason
Название: Cafer`s Mood Stabilizers and Antiepileptics: Drug Interactions and Trade/generic Name Pairings of Medications for Bipolar and Seizure Disorders
ISBN: 1735090123 ISBN-13(EAN): 9781735090122
Издательство: Неизвестно
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Cafer's Psychopharmacology is an essential series for any prescriber of psychiatric medication. Filled with pictures, this book makes complex concepts easy to understand and provides tools for remembering more than you thought possible.

To help you match trade names with generic names of 39 medications, this book features mascots akin to the Xyzal "Wise Owl" and Myrbetriq Bladder characters. Each medication's mascot is incorporated into a visual-mnemonic framework designed for recollection of pharmacokinetic interactions.

For instance, CYP2C19 substrates are represented as flowers with CYP2C19 inhibitors as watering cans to make the flowers grow. CYP1A2 substrates are trees to be chopped down by axes (CYP1A2 inducers). Lithium is a battery and anything that interferes with its renal excretion is depicted as a battery charger.

In addition to lithium, this book includes all of the major antiepileptic drugs (encompassing all of the mood stabilizers other than lithium) and all available benzodiazepines (about half of which are FDA approved for treatment of seizure disorders).

Автор: Talevi
Название: Antiepileptic Drug Discovery
ISBN: 1493963538 ISBN-13(EAN): 9781493963539
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This thorough volume delves into antiepileptic drug discovery with a comprehensive collection of innovative approaches for the development of antiepileptic therapies, focusing on novel molecular targets for antiepileptic drugs, computer-aided approaches for the identification of new drug candidates, and therapeutic strategies to overcome refractory epilepsy. The last section illustrates the potential benefits that network pharmacology and rational drug repurposing could bring to the antiepileptic drug discovery community. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of detailed description and implementation advice to ensure results in the laboratory.

Автор: Patsalos Philip
Название: Epilepsy Prescriber`s Guide to Antiepileptic Drugs
ISBN: 1108453201 ISBN-13(EAN): 9781108453202
Издательство: Cambridge Academ
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Цена: 9186.00 р.
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Описание: This fully updated book is an authoritative reference guide for the spectrum of diverse clinicians and allied health professionals who prescribe antiepileptic drugs in contemporary clinical practice. It includes clear information on thirty-five antiepileptic drugs, including newly-approved drug brivaracetam, and is essential for quick reference reading.

Автор: M.J. Eadie; F. Vajda
Название: Antiepileptic Drugs
ISBN: 3642642446 ISBN-13(EAN): 9783642642449
Издательство: Springer
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Цена: 20896.00 р.
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Описание: With contributions by numerous experts

Автор: Pohlmann-Eden, Bernd; Steinhoff, Bernhard J.
Название: Understanding Antiepileptic Drugs
ISBN: 0199358915 ISBN-13(EAN): 9780199358915
Издательство: Oxford Academ
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Описание: Written by two world experts, Understanding Antiepileptic Drugs describes the profiles of all current antiepileptic drugs comprehensively with all side effects. Understandable and well organized this book is unique in its kind and crucial for both patients and health cafe professionals dealing with epilepsy.

Автор: Patwardhan, Bhushan
Название: Innovative Approaches in Drug Discovery
ISBN: 0128018143 ISBN-13(EAN): 9780128018149
Издательство: Elsevier Science
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Цена: 11115.00 р.
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Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevant tools and technologies, the need is great and the time is now for a renewed commitment towards expanding the repertoire of medicines.a By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences.

Автор: Adejare, Adeboye
Название: Drug Discovery Approaches for the Treatment of Neurodegenerative
ISBN: 0128028106 ISBN-13(EAN): 9780128028100
Издательство: Elsevier Science
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Цена: 17517.00 р.
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Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer's Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer's Disease and illustrating the paradigm necessary to ensure future research and treatment success.

Автор: Asadi-Pooya Ali A., Sperling Michael R.
Название: Antiepileptic Drugs: A Clinician`s Manual
ISBN: 0190214961 ISBN-13(EAN): 9780190214968
Издательство: Oxford Academ
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Цена: 8395.00 р.
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Описание: This concise handbook provides practical, up-to-date clinical guidance on effective selection, prescription, and usage of antiepileptic drugs for patients with epilepsy in various medical conditions and in a variety of clinical contexts. This text discusses choosing drugs when faced with various medical comorbidities; how to correctly prescribe, titrate, and taper drugs; how to monitor drug efficacy and side effects; how to diagnose and manage toxicity; how antiepileptic drugs interact with other medications; and comprehensive coverage of current treatment options.

Key Feature of this Manual Include
� A brief formal discussion of the basic pharmacology of each antiepileptic drug, with an emphasis on how to select and use anti-epileptic drugs in a variety of clinical contexts.
� Discussions of antiepileptic drugs approved for epilepsy since 2009.
� New research about already existing antiepileptic drugs.
� References for further reading that are oriented toward utility in clinical practice.

Antiepileptic Drugs: A Clinician's Manual fills an unmet need as a practical, patient-oriented reference and leads to improved patient care. Supported by practical, clinical knowledge and experience, this is the perfect guide for physicians looking to ensure safe practices in antiepileptic drug therapy.

Автор: Hans-Hasso Frey; D. Janz
Название: Antiepileptic Drugs
ISBN: 3642695205 ISBN-13(EAN): 9783642695209
Издательство: Springer
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Цена: 16979.00 р.
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Описание: With contributions by numerous experts

Автор: Speck-Planche, Alejandro
Название: Multi-Scale Approaches in Drug Discovery
ISBN: 0081011296 ISBN-13(EAN): 9780081011294
Издательство: Elsevier Science
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Цена: 27791.00 р.
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Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents.

Автор: Wang
Название: Predictive ADMET: Integrated Approaches in Drug Discovery and Development
ISBN: 1118299922 ISBN-13(EAN): 9781118299920
Издательство: Wiley
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Цена: 21376.00 р.
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Описание: By guiding in the application of techniques and tools for predicting ADMET outcomes in drug candidates, Predictive ADMET offers a road map for drug discovery scientists to generate effective and safe drugs for unmet medical needs.