This title includes a number of Open Access chapters.
This new volume on gene expression and epigenetics discusses environmental effects related to specific gene expression. The book also shows methods for bioinformatic analysis of the epigenome. The book is broken into two sections: the first looks at eukaryotic DNA methylation and the second addresses how to integrate genomic medicine into clinical practice.
The book includes chapters on these topics:
- Gene expression in colon cancer tissue
- Epigenetics in human acute kidney injury
- Embryologically relevant candidate genes in MRKH patients
- DNA methylation in common skeletal disorders
- Causal relationships in genomics
- Predicting severe asthma exacerbations in children
- Epigenetic understanding of gene-environment interactions in psychiatric disorders
Описание: This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitative fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.
Описание: This volume summarizes the state-of-the-art in the fast growing research area of modeling the influence of information-driven human behavior on the spread and control of infectious diseases. In particular, it features the two main and inter-related “core” topics: behavioral changes in response to global threats, for example, pandemic influenza, and the pseudo-rational opposition to vaccines. In order to make realistic predictions, modelers need to go beyond classical mathematical epidemiology to take these dynamic effects into account. With contributions from experts in this field, the book fills a void in the literature. It goes beyond classical texts, yet preserves the rationale of many of them by sticking to the underlying biology without compromising on scientific rigor. Epidemiologists, theoretical biologists, biophysicists, applied mathematicians, and PhD students will benefit from this book. However, it is also written for Public Health professionals interested in understanding models, and to advanced undergraduate students, since it only requires a working knowledge of mathematical epidemiology.
Автор: Samantha Adams; Nadezhda Purtova; Ronald Leenes Название: Under Observation: The Interplay Between eHealth and Surveillance ISBN: 3319483404 ISBN-13(EAN): 9783319483405 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The essays in this book clarify the technical, legal, ethical, and social aspects of the interaction between eHealth technologies and surveillance practices.
Описание: This monograph demonstrates the interplay between Shannon information and semantic information in cognition. In the process of information adaptation, quantitative variations in Shannon`s information entail different meanings while different meanings affect the quantity of information.
Описание: Buckle up for the greatest road trips on Earth. This beautiful paperback showcases 50 iconic routes, from Hawaii`s Hana Highway and Vietnam`s Ho Chi Minh Road, to Utah`s National Park Circuit and Germany`s Black Forest High Road. With first-hand accounts, stunning photographs and practical advice, it will inspire all motorists to hit the open road.
Автор: Muthusamy Lakshmanan; Dharmapuri Vijayan Senthilku Название: Dynamics of Nonlinear Time-Delay Systems ISBN: 3642266495 ISBN-13(EAN): 9783642266492 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Dynamics of Nonlinear Time-Delay Systems presents the fundamentals of chaotic time-delay systems and their synchronization, with an emphasis on the effects of time-delay feedback. Special attention is devoted to scalar chaotic/hyperchaotic time-delay systems, which includes some higher order models.
Описание: An overview of recent advances in the stability and oscillation of autonomous delay differential equations. Topics covered include linear and nonlinear delay and integrodifferential equations, which have potential applications in biological and physical dynamic processes.
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