Advances in Host-Directed Therapies Against Tuberculosis, Karakousis Petros C., Hafner Richard, Gennaro Maria Laura
Название: Host-Directed Therapies for Tuberculosis ISBN: 3039435019 ISBN-13(EAN): 9783039435012 Издательство: Неизвестно Рейтинг: Цена: 6901.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
TB is considered as one of the oldest documented infectious diseases in the world and is believed to be the leading cause of mortality due to a single infectious agent. Mtb, the causative agent responsible for TB, continues to afflict millions of people worldwide. Furthermore, one-third of the entire world's population has latent TB. Consequently, there has been a worldwide effort to eradicate and limit the spread of Mtb through the use of antibiotics. However, management of TB is becoming more challenging with the emergence of drug-resistant and multi-drug resistant strains of Mtb. Furthermore, when administered, many of the anti-TB drugs commonly present severe complications and side effects. Novel approaches to enhance the host immune responses to completely eradicate Mtb infection are urgently needed. This Special Issue will therefore cover most recent advances in the area of host-directed therapies for TB.
Автор: Janusz W. Rak Название: Oncogene-Directed Therapies ISBN: 1468497383 ISBN-13(EAN): 9781468497380 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer.
Описание: Dissertation Discovery Company and University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "Muscle-directed Gene and Enzyme Replacement Therapies for Glycogen Storage Disorder Type II Pompe Disease" by Thomas Joseph Fraites Jr, was obtained from University of Florida and is being sold with permission from the author. A digital copy of this work may also be found in the university's institutional repository, IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.
Автор: Francisco Aboitiz; Diego Cosmelli (Eds.) Название: From Attention to Goal-Directed Behavior ISBN: 3540705724 ISBN-13(EAN): 9783540705727 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presents a view of neurodynamical approaches to attentional mechanisms with a take on neuropsychiatric illnesses which can shed light on these problems, specifically ADHD and schizophrenia. This work provides evidence pointing to genetic and neurochemical factors as important elements determining individual diversity in neurodynamical patterns.
Experience and research are clear: when pastors are criticized, attacked, and betrayed, they become confused, frustrated, and at times angry, and consequently, they experience acute pain--often causing deep wounds. Often not sure what to do, some quit their ministry, while others leave it altogether. But most serve for the long haul.
Starting out in ministry, the vast majority of pastors have no clue about the conflict they will encounter, nor how to effectively deal with it.
But pastors want answers....and Moses provides that solution.
How Moses responded to the conflict he faced when leading Israel in the wilderness revealed a unique and comprehensive arrangement of leadership principles. The principles lay a solid foundation for this Pastor-Directed Model to equip pastors to successfully address conflict in a way that brings glory to God.
Based on Moses' example, this model is founded on seven essential priorities that every pastor should practice at all times, in order to carry out four simple, yet practical steps to address conflict successfully. This comprehensive approach will glorify God and resolve conflict, bringing peace to people's lives and churches.
Endorsements
. . . In this book, Gib Allen has provided priceless insight into a solution to all the petty ills that confront our churches today. Hopefully you will have the opportunity to read this volume carefully. Paige Patterson, President The Sandy CREEK Foundation Dallas, Texas
Gib Allen shares his years of experience and research in handling conflict as a pastor ... This book provides a sophisticated, practical model for resolving conflict in churches, a beneficial resource for anyone in ministry. Joshua E. Williams, Ph.D. Associate Professor of Old Testament Southwestern Baptist Theological Seminary
Managing church conflict is part of being an effective pastor. The biblical strategies in this helpful book reveal insightful ways to fulfill this difficult part of local church leadership...This book charts a course to that end. Jeff Iorg, President Gateway Seminary
Автор: Fajstrup Lisbeth, Goubault Eric, Haucourt Emmanuel Название: Directed Algebraic Topology and Concurrency ISBN: 3319792172 ISBN-13(EAN): 9783319792170 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This monograph presents an application of concepts and methods from algebraic topology to models of concurrent processes in computer science and their analysis. Taking well-known discrete models for concurrent processes in resource management as a point of departure, the book goes on to refine combinatorial and topological models.
Автор: Bryan Cardinale-Powell, Marc DiPaolo Название: Devised and Directed by Mike Leigh ISBN: 1623565995 ISBN-13(EAN): 9781623565992 Издательство: Bloomsbury Academic Рейтинг: Цена: 23760.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Renowned for making films that are at once sly domestic satires and heartbreaking 'social realist' dramas, British writer-director Mike Leigh confronts his viewers with an un-romanticized dramatization of modern-day society in the hopes of inspiring them to strive for greater self-awareness and compassion for others. This collection features new, interdisciplinary essays that cover all phases of the BAFTA-award-winner's film career, from his early made-for-television film work to his theatrical releases, including Life is Sweet (1990), Naked (1993), Secrets & Lies (1996), Career Girls (1997), Topsy-Turvy (1999), All or Nothing (2002), Vera Drake (2004), Happy-Go-Lucky (2008) and Another Year (2010).
With contributions from international scholars from a variety of fields, the essays in this collection cover individual films and the recurring themes and motifs in several films, such as representations of class and gender, and overt social commentary and political subtexts. Also covered are Leigh's visual stylizations and storytelling techniques ranging from explorations of the costume design to set design to the music and camerawork and editing; the collaborative process of 'devising and directing' a Mike Leigh film that involves character-building, world-construction, plotting, improvisations and script-writing; the process of funding and marketing for these seemingly 'uncommercial' projects, and a survey of Leigh's critical reception and the existing writing on his work.
Описание: This book is based on the reality that we cannot assume learners will become self-directed as they mature. It uncovers the tools and strategies that adult medical educators can utilise to develop the learning skills of a self-directed learner.
Описание: Seminar paper from the year 2006 in the subject Pedagogy - Science, Theory, Anthropology, grade: 1,7, University of Wuppertal, course: Theory of Learning, language: English, abstract: This term paper explores the subject "Model-directed Learning, Albert Bandura's Social Cognitive Learning Theory and its social-psychological Significance for School and Instruction". The topic touches on several complex scientific areas that cannot be exhaustively discussed and in part can only contribute in a more generalized form to the scope of this term paper. Hence, there is the challenge of setting boundaries at first. The main focus of this paper is on the social cognitive learning theory according to Albert Bandura, with its central statements serving as the theoretical foundation of the paper as a whole. The aim is to investigate, which basic principles Bandura is adopting from human behavior, how he does explain and analyze this approach. This theoretical rationale should be set up in the socio-psychological context of school and instruction. Hence, a main goal of this paper is to establish a theory-practice relevance. In other words, the focus is to investigate which consequences are arising from the social cognitive learning theory for school, teaching, education, and studying. A key aspect of the social cognitive learning theory is model-based learning, thus, the assumption that human learning can happen through observation and imitation of others. In a society, in which humans strive for individuality and originality, imitation and simulation are associated with negative characteristics. Nevertheless, imitation behavior plays an important role even in every day situations. A person's aggressive behavior or drug habit is often rationalized with the assumption that this behavior was copied from friends, or was due to the influence of others, or being surrounded with the wrong people. This term paper attempts to show the scientific reasoning behind this "everyday wisdom",
Описание: Proposing a modified concept of care management, DIRECTED CARE captures the leadership and management expertise of professional nurses to guide individuals to more effective and efficient utilization of health care resources and to influence their personal health behaviors toward optimal wellness. The discussion sheds the passive patient image as merely a recipient of services. It is replaced with active participation of a health care consumer in collaboration with the health care providers where for and to become with. An upstream, preventive care approach is promoted throughout the book. Registered nurses are presented working in tandem with their nurse practitioner colleagues as clinical team-based members in an ambulatory primary care setting and in a proposed Patient-Centered Medical Home model. -Professional nurses are described as independent providers of DIRECTED CARE activities. -Wellness care is segmented from illness care within the discussion of the DIRECTED CARE concept. -Tailored communication is emphasized as an important part of interactions with health care consumers. -A Summary Health Care Record and Health Monitoring Plan are presented to illustrate the manner in which health data can be organized for individual health care consumers that result in data consolidation and review simplification.
Название: Sensory-Directed Flavor Analysis ISBN: 0367390396 ISBN-13(EAN): 9780367390396 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Today, flavor chemists can generate copious amounts of data in a short time with relatively little effort using automated solid phase micro-extraction, Gerstel-Twister(R) and other extraction techniques in combination with gas chromatographic (GC) analysis. However, more data does not necessarily mean better understanding. In fact, the ability to extract, isolate, and concentrate potential flavor-important chemicals from complex food systems has surpassed the ability to understand how the chemical data relates to flavor.
Sensory-Directed Flavor Analysis helps chemists unlock the flavor secrets that may be hiding in their chromatograms by translating cold hard numbers into a better understanding of the sense of smell and taste. The author integrates the two disciplines of sensory science and analytical chemistry, encouraging sensory scientists to incorporate more analytical data while encouraging analytical chemists to include more sensory techniques. Using more ancillary techniques helps each discipline elucidate how various chemical constituents influence food flavor and appeal. The book discusses important enabling technologies and analytical methods including GC-olfactometry (GC-O), combination GC-O and multi-dimensional GC, the application of odor activity values (OAVs), and recombination studies, as well as solid-phase dynamic extraction and preseparation techniques. A broad array of applications, in addition to dozens of tables, graphs, gas chromatograms, and pictures, are included throughout the book. Highlighting the advantages and disadvantages and the appropriate circumstances for each method of analysis, Sensory-Directed Flavor Analysis offers flavor scientists an essential reference to deepen their understanding of the function of chemicals on the perception of taste.
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