Novel (Trans)Dermal Drug Delivery Strategies: Micro- And Nano-Scale Assessments, Hazel Garvie-Cook
Автор: Garvie-Cook Hazel Название: Novel (Trans)dermal Drug Delivery Strategies ISBN: 3319289004 ISBN-13(EAN): 9783319289007 Издательство: Springer Рейтинг: Цена: 14365.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This work represents an inventive attempt to apply recent advances in nanotechnology to identify and characterise novel polymer systems for drug delivery through the skin.
Автор: Lionel Trottet; Howard Maibach, MD Название: Dermal Drug Selection and Development ISBN: 3319595032 ISBN-13(EAN): 9783319595030 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The authors show how the pharmaceutical industry faces the development of dermal drugs and provide the only book of its kind that describes how the industry develops and selects dermal drugs, complete with the challenges and opportunities of the field.
Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites.
To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.
Описание: Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites.
To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.
Название: Dermal Drug Delivery ISBN: 1466582707 ISBN-13(EAN): 9781466582705 Издательство: Taylor&Francis Рейтинг: Цена: 27562.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
With the continued advancement of better-quality control and patient outcome reporting systems, changes in the development, control, and regulation of all pharmaceutical delivery systems including transdermal and topical products have been happening on a continuous basis. In light of various quality issues that have been reported by patients and practitioners resulting in the recall or removal of products from the market, both the pharmaceutical industries and regulatory agencies have been adopting new measures to address these issues. With chapters written by experts in this field, this book takes a 21st century multidisciplinary and cross-functional look at these dosage forms to improve the development, design, manufacturing, quality, clinical performance, safety, and regulation of these products.
This book offers a wealth of up-to-date information organized in a logical sequence corresponding to various stages of research, development, and commercialization of dermal drug delivery products. The authors have been carefully selected from different sectors of pharmaceutical science for their expertise in their selected areas to present objectively a balanced view of the current state of these products development and commercialization via regulatory approval. Their insights will provide useful information to others to ensure the successful development of the next generation dermal drug products.
Key Features:
Presents current advancements including new technologies of transdermal and topical dosage forms.
Presents challenges in the development of the new generation of transdermal and topical dosage forms.
Introduces new technologies and QbD (quality by design) aspects of manufacturing and control strategies.
Includes new perspectives on pre-clinical and clinical development, regulatory considerations, safety and quality.
Discusses regulatory challenges, gaps, and future considerations for dermal drug delivery systems.
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