Tuberculosis Host-Pathogen Interactions, Cirillo Jeffrey D., Kong Ying
Автор: Jurgen Popp Название: Modern Techniques for Pathogen Detection ISBN: 3527335161 ISBN-13(EAN): 9783527335169 Издательство: Wiley Рейтинг: Цена: 12524.00 р. 17891.00-30% Наличие на складе: Есть (1 шт.) Описание: This book gives a comprehensive overview of common and modern techniques for pathogen diagnostics. The first chapter provides an outline of unmet medical needs in life–threatening infections followed by an overview of routine identification methods currently used, including their background, strengths and weaknesses, as well as a comparison to newer methods. The following chapters then cover novel methods already widelyused and their potential for routine pathogen detection. An outstanding resource for all medical laboratories and clinical as well as bioanalytical institutions dealing with infectious diseases.
Описание: This book provides an extensive review of research into Campylobacter, Helicobacter and Arcobacter species found in poultry. It includes the epidemiology, diagnosis, immune response and disease control of these organisms in commercial poultry production. Antimicrobial resistance, and the incidence and human disease potential of these bacteria is also discussed. A global perspective is presented by experts from four continents – South America, North America, Europe and Africa. This reference work will be of value to the poultry industry, research laboratories, public health workers and students. An extensive overview of the relevant literature is provided by the reference lists at the end of each chapter.
Автор: G Singh Chhatwal Название: Host-Pathogen Interactions in Streptococcal Diseases ISBN: 3642363393 ISBN-13(EAN): 9783642363399 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers comprehensive coverage of streptococcal diseases, benefiting clinicians, microbiologists, public health workers, students of medicine and microbiology and research scientists working in this field.
Описание: This volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between host immune systems and invading pathogens has given rise to corresponding processes that produce molecular variation. Whether in mollusks or human beings, various host somatic mechanisms have evolved independently, providing responses to counter rapidly-changing pathogens. The pathways they utilize can include non-heritable changes involving RNA and post-translational modifications, or changes that produce somatic DNA recombination and mutation. For infectious organisms such as protozoans and flatworms, antigenic variation is central to their survival strategy. Evolving the ability to evade the host immune system not only increases their chances of survival but is also necessary for successful re-infection within the host population.
Описание: This volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between host immune systems and invading pathogens has given rise to corresponding processes that produce molecular variation. Whether in mollusks or human beings, various host somatic mechanisms have evolved independently, providing responses to counter rapidly-changing pathogens. The pathways they utilize can include non-heritable changes involving RNA and post-translational modifications, or changes that produce somatic DNA recombination and mutation. For infectious organisms such as protozoans and flatworms, antigenic variation is central to their survival strategy. Evolving the ability to evade the host immune system not only increases their chances of survival but is also necessary for successful re-infection within the host population.
Описание: Antibiotics have indeed brought unprecedented health benefits, protection from and cure of bacterial diseases during the past 50 years. They are crum- bling because we wittingly or unwittingly created selective con- ditions for the emergence of superior pathogens that can no longer be controlled by antibiotics.
Название: Escherichia coli, a versatile pathogen ISBN: 3319996630 ISBN-13(EAN): 9783319996639 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Escherichia coli is a facultative anaerobic Gamma-proteobacterium, which belongs to the family Enterobacteriaceae. While being an important constituent of the normal gut microbiota, specialized E. coli clones have acquired genetic elements that allow them to compete with the endogenous commensals, colonise normally sterile niches and cause disease. E. coli pathotypes can cause intestinal and extra intestinal infections (e.g. UTI, sepsis) and associate with mammalian cells while being extra- or intra-cellular. In recent years, E. coli infections have become a serious clinical problem, due to the rapid spread of antibiotic resistance. Thus, infections with intestinal E. coli (e.g. E. coli O104) or extraintestinal pathogenic strains (e.g. E. coli ST131) are becoming difficult to treat and are often lethal. Consequently, there is a pressing need to develop alternative control measures, including the identification of new drug targets and development of vaccines that offer lasting protection.This volume focuses on several types of E. coli infections (intestinal and extraintestinal), virulence factors, and E. coli pandemics. It addresses the problem of antibiotic resistance, and a dedicated chapter discusses the need to develop alternative control measures. Given its depth and breadth of coverage, the book will benefit all those interested in the biology, genetics, physiology and pathogenesis of E. coli, and in related vaccine development.
Автор: Heinz Mehlhorn; Kevin S. W. Tan; Hisao Yoshikawa Название: Blastocystis: Pathogen or Passenger? ISBN: 3642433065 ISBN-13(EAN): 9783642433061 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume summarizes what we know about blastocystis, the enigmatic organism whose pathogenesis we have recognized for a century but whose mechanisms remain mysterious to this day. It examines everything from its epidemiology to its varied clinical aspects.
Автор: Lion Название: Human Fungal Pathogen Identification ISBN: 1493965131 ISBN-13(EAN): 9781493965137 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume presents timely and authoritative content offering a comprehensive overview of the current state of the art in fungal diagnostics. Moreover, it addresses on-going developments expected to provide a basis for targeted treatment strategies resulting in improved outcome of invasive mycoses. The knowledge of host-related predisposing factors and stratified treatment options facilitating timely onset of adequate antifungal therapy are critical for successful clinical management and outcome of invasive fungal disease (IFD), requiring not only rapid diagnosis of a fungal infection and identification of the causative species, but also assessment of pathogen/host factors related to pathogenicity, susceptibility, and response to treatment. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Human Fungal Pathogen Identification: Methods and Protocols serves as an ideal reference for researchers investigating the ever-growing worldwide healthcare problems involving fungal infections.
Автор: Mario Campa; Mauro Bendinelli; Herman Friedman Название: Pseudomonas aeruginosa as an Opportunistic Pathogen ISBN: 1461363241 ISBN-13(EAN): 9781461363248 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Assembling the latest research by an international group of contributors, this volume covers the epidemiology, pathogenesis, clinical features, and control measures of this elusive microorganism.
Автор: Karen Joy Shaw Название: Pathogen Genomics ISBN: 1468496832 ISBN-13(EAN): 9781468496833 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The authors` cross-disciplinary approach, with expertise acquired from studying disease-causing viruses, bacteria, fungi, and protozoa, reveals how sequence information from diverse pathogens has uncovered novel targets for drug discovery, antigenic determinants for vaccine development, as well as diagnostic tools.
Автор: Jeffrey D. Cirillo; Ying Kong Название: Tuberculosis Host-Pathogen Interactions ISBN: 3030253805 ISBN-13(EAN): 9783030253806 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes the progress in studies of tuberculosis host-pathogen interactions from several perspectives: molecular microbiology, immunology, animal models, clinical studies, epidemiology, and drug discovery. Tuberculosis (TB) remains a severe global public health problem. Complex interactions between environmental, microbial and host factors lead to clinically relevant infections. Studies on bacterial virulence, host-genetic, and immunological factors contributing to the susceptibility to TB provide an ever-growing foundation of knowledge that is critical to finding new interventions. Studies of immune mechanisms against M. tuberculosis infection have identified immunological markers associated with specific phenotypes in the host, providing insight into how they may be used to augment current treatment strategies. Recent advances in diagnosis, therapeutics and vaccines, as well as basic-research oriented studies have shed light on the development of new directions for prevention, treatment and control of TB. Improved understanding of the interplay between the bacterium and host is a key component of reducing incidence worldwide.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
