Cullin-Ring Ligases and Protein Neddylation: Biology and Therapeutics, Sun Yi, Wei Wenyi, Jin Jianping
Автор: Gregory J. Seymour; Mary P. Cullinan; Nicholas C.K Название: Oral Biology ISBN: 1493982729 ISBN-13(EAN): 9781493982721 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface... Table of Contents... Contributing Authors...
Part I Saliva and Other Oral Fluids
1. Salivary Diagnostics using Purified Nucleic Acids Paul D. Slowey 2. RNA Sequencing Analysis of Salivary Extracellular RNA Blanca Majem, Feng Li, Jie Sun, and David T.W. Wong 3. Qualitative and Quantitative Proteomic Analysis of Oral Fluids in Health and Periodontal Disease by Mass Spectrometry Erdjan Salih 4. Antioxidant Micronutrients and Oxidative Stress Biomarkers Iain L.C. Chapple, Helen R. Griffiths, Mike R. Milward, Martin R. Ling, and Melissa M. Grant 5. NMR-Based Metabolomics of Oral Biofluids Horst Joachim Schirra and Pauline J. Ford 6. Gene Therapy of Salivary Diseases Bruce J. Baum, Sandra Afione, John a. Chiorini, Ana P. Cotrim, Corinne M. Goldsmith, and Changyu Zheng
Part II Molecular Biosciences 7. The Oral Microbiota in Health and Disease: An Overview of Molecular Findings Josй F. Siqueira, Jr., and Isabela N. Rфзas 8. Microbial Community Profiling using Terminal Restriction Fragment Length Polymorphism (T-RFLP) and Denaturing Gradient Gel Electrophoresis (DGGE) Josй F. Siqueira, Jr., Mitsuo Sakamoto, and Alexandre S. Rosado 9. Analysis of 16S rRNA Gene Amplicon Sequences using the QIIME Software Package Blair Lawley and Gerald W. Tannock 10. Adhesion of Yeast and Bacteria to Oral Surfaces Richard D. Cannon, Karl M. Lyons, Kenneth Chong, Kathryn Newsham-West, Kyoko Niimi, and Ann R. Holmes 11. Quantitative Analysis of Periodontal Pathogens by Real-Time Polymerase Chain Reaction Ma Josй Marin, Elena Figuero, David Herrera, and Mariano Sanz 12. Methods to Study Antagonistic Activities Among Oral Bacteria Fengxia Qi and Jens Kreth 13. Natural Transformation of Oral Streptococci by Use of Synthetic Pheromones Gabriela Salvadori, Roger Junges, Rabia Khan, Heidi A. Еmdal, Donald Morrison, and Fernanda C. Petersen 14. Markerless Genome Editing in Competent Streptococci Roger Junges, Rabia Khan, Yanina Tovpeko, Heidi A. Еmdal, Fernanda C. Petersen, and Donald A. Morrison 15. Tools and Strategies for Analysis of Genome-Wide and Gene-Specific DNA Methylation Patterns Aniruddha Chatterjee, Euan J. Rodger, Ian M. Morison, Michael R. Eccles, and Peter A. Stockwell 16. Generating Multiple Base-Resolution DNA Methylomes using Reduced Representation Bisulfite Sequencing Aniruddha Chatterjee, Euan J. Rodger, Peter a. Stockwell, Gwenn Le Mйe, and Ian M. Morison 17. A Protocol for the Determination of the Methylation Status of Gingival Tissue DNA at Specific CpG Islands Trudy J. Milne 18. Genome-Wide Expression Analysis of Periodontal Cells and Tissues Moritz Kebschull, Claudia Hьlsmann, Per Hoffmann, and Panos N. Papapanou 19. Differential Expression and Functional Analysis of High-Throughput -Omics Data Using Open Source Tools Moritz Kebschull, Julia M. Fittler, Ryan T. Demmer, and Panos N. Papapanou 20. Exploring Genome-Wide Expression Profiles Using Machine Learning Techniques Moritz Kebschull and Panos N. Papapanou Part III Cells and Tissues 21. Embryonic Explant Culture: Studying Effects of Regulatory Molecules on Gene Expression in Craniofacial Tissues Katja Nдrhi 22. Oral Epithelial Cell Culture Model for Studying the Pathogenesis of Chronic Inflammatory Disease Mike R. Milward, Martin R. Ling, Melissa M. Grant, Iain L.C. Chapple 23. Fabrication and Characterization of Decellularized Periodontal Ligament Cell Sheet Constructs Amro Farag, Cedryck Vaquette, Dietmar W. Hutmacher, P. Mark Bartold, and Saso Ivanovski 24. A Method to Isolate, Purify and Characterize Human Periodontal Ligament Stem Cells
Автор: Yi Sun; Wenyi Wei; Jianping Jin Название: Cullin-RING Ligases and Protein Neddylation ISBN: 9811510245 ISBN-13(EAN): 9789811510243 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation.
Автор: Antje Chang; Dietmar Schomburg; Ida Schomburg Название: Class 4-6 Lyases, Isomerases, Ligases ISBN: 366251883X ISBN-13(EAN): 9783662518830 Издательство: Springer Рейтинг: Цена: 46118.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Springer Handbook of Enzymes provides data on enzymes sufficiently well characterized. It offers concise and complete descriptions of some 5,000 enzymes and their application areas. Data sheets are arranged in their EC-Number sequence and the volumes themselves are arranged according to enzyme classes. This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications.
Автор: Dietmar Schomburg; Ida Schomburg; Antje Chang Название: Class 3.4–6 Hydrolases, Lyases, Isomerases, Ligases ISBN: 3642362591 ISBN-13(EAN): 9783642362590 Издательство: Springer Рейтинг: Цена: 49631.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Springer Handbook of Enzymes covers 5,000 enzymes and their applications. Data sheets are arranged in their EC-Number sequence and the volumes themselves are arranged by enzyme class. This volume covers Class 3.4-6 Hydrolases, Lyases, Isomerases, Ligases.
Автор: Gregory J. Seymour; Mary P. Cullinan; Nicholas C.K Название: Oral Biology ISBN: 1493966839 ISBN-13(EAN): 9781493966837 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This second edition volume presents a selection of cellular and molecular techniques that can be adapted to cover a range of applications and diseases. The book is divided into three sections: saliva and oral diseases, molecular biosciences, and cell and tissues. The first section contains chapters that discuss proteomic analyses by mass spectrometry and NMR-based metabolomics that can be used to not only study saliva, but also to assess other oral fluids such as gingival crevicular fluid. The second section contains chapters that profile oral microbial communities, quantitative real-time PCR, and adhesion of yeast and bacteria to oral surfaces. The third section deals with a range of approaches that enable the behavior of cells and tissues in both health and disease to be analyzed at the molecular level. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Oral Biology: Molecular Techniques and Applications, Second Edition is a useful resource for oral biologists at all levels (students, early career researchers, and experienced veterans), and it provides a ready reference to new techniques and approaches that can be used to answer numerous specific scientific questions that may lead to a deeper understanding and treatments of oral diseases.
Автор: Hiroyuki Inuzuka; Wenyi Wei Название: SCF and APC E3 Ubiquitin Ligases in Tumorigenesis ISBN: 3319050257 ISBN-13(EAN): 9783319050256 Издательство: Springer Рейтинг: Цена: 9141.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Gregory J. Seymour; Mary P. Cullinan; Nicholas C.K Название: Oral Biology ISBN: 149396142X ISBN-13(EAN): 9781493961429 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It is generally recognized that the knowledge and research base that underpins dentistry lies in the biological and physical sciences. In this context, the major advances in these sciences over the past two decades have come through the application of molecular bi- ogy and nanotechnology. These advances are currently impacting on the diagnosis and treatment of a wide range of human diseases and it is essential that dental research, education, and practice keep pace with this rapidly advancing ?eld. As pointed out by Ford et al. (1): The de?nition of disease is also changing. Previously, disease was understood to be the presence of symptoms or of a particular phenotype. With increasing knowledge of the genetic basis of many diseases, this de?nition is changing to become the presence of a genotype conferring a pre-disposition to clinical symptoms or phenotype (Ford et al. (1)). This changing de?nition of disease means that today’s undergraduate or graduate student in dentistry (and its related ?elds) must be in a position not only to acquire new knowledge in the future but also to be able to evaluate the information and apply it in a clinically relevant setting. This naturally positions oral biology as an integral part of any dentally related professional’s repertoire of knowledge. There are as many topics in oral biology as there are the number of sites and micro- vironments within the oral cavity.
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