Описание: This thesis covers various facets of brain image computing methods and illustrates the scientific understanding of neurodegenerative disorders based on four general aspects of multimodal neuroimaging computing: neuroimaging data pre-processing, brain feature modeling, pathological pattern analysis, and translational model development.
Автор: Jos? M. Fuentes Название: Toxicity and Autophagy in Neurodegenerative Disorders ISBN: 331913938X ISBN-13(EAN): 9783319139388 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.
Автор: Jos? M. Fuentes Название: Toxicity and Autophagy in Neurodegenerative Disorders ISBN: 3319382128 ISBN-13(EAN): 9783319382128 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.
Автор: Md. Sahab Uddin, Ghulam Md Ashraf Название: Quality Control of Cellular Protein in Neurodegenerative Disorders ISBN: 1799813177 ISBN-13(EAN): 9781799813170 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 39640.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity. Though multiple factors like aging, oxidative stress, gene inconsistency, etc. are responsible for the dysfunction of the protein quality control system, targeting protein quality control has become an auspicious approach to block the propagation of neurodegeneration.
Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the theoretical and practical methods of protein quality control systems and potential therapeutic approaches to halt the development and propagation of neurodegenerative disorders. Featuring coverage on a broad range of topics such as cellular chaperones, protein folding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.
Автор: Mark P. Mattson Название: Pathogenesis of Neurodegenerative Disorders ISBN: 1617372153 ISBN-13(EAN): 9781617372155 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As the average life expectancy of many populations throughout the world increases, so to does the incidence of such age-related neurodegenerative disorders as Alzheimer`s, Parkinson`s, and Huntington`s diseases.
Описание: Promising effects in mice of immunization by ss-amyloid stimulated substantial research efforts and high hopes.
Автор: V.M.-Y. Lee; J.Q. Trojanowski; L. Buee; Y. Christe Название: Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders ISBN: 3642086497 ISBN-13(EAN): 9783642086496 Издательство: Springer Рейтинг: Цена: 33401.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this volume are contributions based on a meeting arranged by the WHO and the Fondation IPSEN. The scientists focus on neurodegenerative disorders like Alzheimer`s Disease, Chromosome 17-Linked Dementia, Parkinson`s Disease and disorders with tauopathies.
Автор: Reeve Название: Mitochondrial Dysfunction in Neurodegenerative Disorders ISBN: 3319286358 ISBN-13(EAN): 9783319286358 Издательство: Springer Рейтинг: Цена: 18866.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This second edition brings together up-to-date contributionsfrom leaders in the field internationally on the various ways in whichmitochondrial dysfunction contributes to the pathogenesis of neurodegenerativediseases, including Parkinson’s disease, Alzheimer’s disease and multiplesclerosis. The reader is guided through the basic functions of mitochondria andthe mechanisms that lead to their dysfunction, and on to the consequences ofthis dysfunction for neuronal function before finishing with the modelling ofthese disorders and discussion of new potential therapeutic targets. Additional chapters have been added to the book to reflectadvances in the field and there are many new contributors and topics, includinghow mitochondria are degraded and the interaction of the mitochondria withpathologically relevant proteins. Mitochondrial Dysfunction in Neurodegenerative Disordersprovides an accessible, authoritative guide to this important area forneurologists; research and clinical neuroscientists; neuropathologists; andresidents with an interest in clinical research.
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