Описание: The studies and discourses described touch upon topics that explore biodiversity for the development of disease models, toxicity studies, developmental studies, and harvesting of bioactive compounds for alternative income generation and poverty alleviation, and as a result, bring about economic and ecologic sustainability.
Описание: This book is all about the definition and finding ways to prioritize and accelerate translation research in biomedical sciences and rapidly turning new knowledge into first-in-human studies. It represents an effort to bring together scientists active in various areas of translational research to share science and, hopefully, generate new ideas and potential collaborations. The book provides a comprehensive overview of translational work that includes significant discoveries and pioneering contributions, e.g., in immunology, gene therapy, stem cells and population sciences. It may be used as an advanced textbook by graduate students and even ambitious undergraduates in biomedical sciences. It is also suitable for non-experts, i.e. medical doctors, who wish to have an overview of some of the fundamental models in translational research.Managing the translational enterprise remains a work in progress. The world is changing rapidly, and the scientific world needs to seek new ways to ensure that discoveries get translated for patients efficiently and as quickly as possible. In addition, everyone expects the investment in biomedical research should pay dividends through effective therapeutic solutions. This unique project provides a broad collaborative approach of the international scientific team to present its view and opinion how to cross barriers to incentives for translational research in medical sciences.Contributing to the book is an international team of prominent co-authors. The book consists of unique and widely treated topics, and includes new hypotheses, data and analyses.
Название: Translational bioinformatics applications in healthcare ISBN: 0367705702 ISBN-13(EAN): 9780367705701 Издательство: Taylor&Francis Рейтинг: Цена: 17609.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Translational bioinformatics (TBI) involves development of storage, analytics, and advanced computational methods to harvest knowledge from voluminous biomedical and genomic data into 4P healthcare (proactive, predictive, preventive, and participatory). Translational Bioinformatics Applications in Healthcare offers a detailed overview on concepts of TBI, biological and clinical databases, clinical informatics, and pertinent real-case applications. It further illustrates recent advancements, tools, techniques, and applications of TBI in healthcare, including Internet of Things (IoT) potential, toxin databases, medical image analysis and telemedicine applications, analytics of COVID-19 CT images, viroinformatics and viral diseases, and COVID-19–related research. Covers recent technologies such as Blockchain, IoT, and Big data analytics in bioinformaticsPresents the role of translational bioinformatic methods in the field of viroinformatics, as well as in drug development and repurposing Includes translational healthcare and NGS for clinical applications Illustrates translational medicine systems and their applications in better healthcare Explores medical image analysis with focus on CT images and novel coronavirus disease detectionAimed at researchers and graduate students in computational biology, data mining and knowledge discovery, algorithms and complexity, and interdisciplinary fields of studies, including bioinformatics, health-informatics, biostatistics, biomedical engineering, and viroinformatics.Khalid Raza is an Assistant Professor, the Department of Computer Science, Jamia Millia Islamia (Central University), New Delhi. His research interests include translational bioinformatics, computational intelligence methods and its applications in bioinformatics, viroinformatics, and healt
Описание: A book useful to postgraduate students and researchers in medicinal chemistry and pharmacology, as well as specialists in the acute brain injury field.
Описание: Serving as a practical handbook about ADMET for drug therapy, this book presents effective technologies, methods, applications, data interpretation, and decision-making tactics for pharmaceutical and preclinical scientists.
Sherri M. Biendarra-Tiegs, Frank J. Secreto, and Timothy J. Nelson, M.D., Ph.D. Addressing variability and heterogeneity of induced pluripotent stem cell-derived cardiomyocytes
Justine Bajohr, Maryam Faiz Direct Lineage Reprogramming in the CNS
Yusuke Nakamura, Yasuo Shimizu Induced pluripotent stem cells for regenerative medicine: Quality control based on evaluation of lipid composition
Omair A. Mohiuddin, Brett Campbell, J. Nicholas Poche, Caasy Thomas-Porch, Daniel A. Hayes, Bruce A. Bunnell, Jeffrey M. Gimble Decellularized Adipose Tissue: Biochemical composition, in vivo analysis and potential clinical applications
Цzge Sezin SOMUNCUDECELLULARIZATION CONCEPT IN REGENERATIVE MEDICINE.
Janja Zupan, Matej Drobnič, Klemen Strazar Synovium-derived mesenchymal stem/ stromal cells and their promise for cartilage regeneration
Nur Kьbra Зankirili, Ozlem Altundag, Betьl Зelebi-Saltik Skin stem cells, their niche and tissue engineering approach for skin regeneration
Fatima Aerts-Kaya, Baris Ulum, Aynura Mammadova, Sevil Kцse, Gцzde Aydın, Petek Korkusuz, Duygu Uзkan-Зetinkaya. Neurological regulation of the bone marrow niche
Rokas Miksiunas, Ali Mobasheri Daiva Bironaite Homeobox genes and homeodomain proteins: new insights into cardiac development, degeneration and regeneration
Victor Navarro-Tableros, Yonathan Gomez, Maria Felice Brizzi Giovanni CamussiGeneration of human stem cell-derived pancreatic organoids (POs) for regenerative medicine
Описание: Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome.
Автор: Le Prell Colleen G., Lobarinas Edward, Popper Arthur N. Название: Translational Research in Audiology, Neurotology, and the Hearing Sciences ISBN: 3319821997 ISBN-13(EAN): 9783319821993 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Most scientific training programs provide little or no systematic introduction to the issues, challenges, and obstacles that prevent effective research translation, even though these are the key steps that enable high-impact basic science to ultimately result in significant clinical advances that improve patient outcome. This volume will provide an overview of key issues in translation of research from “bedside to bench to bedside”, not only from the perspective of the key funding agencies, but also from the scientists and clinicians who are currently involved in the translational research process. It will attempt to offer insight into real-world experience with intellectual property and technology transfer activities that can help move auditory technologies ahead, as scientists and clinicians typically have little or no formal training in these areas. Translational Research in Audiology and the Hearing Sciences will be aimed at graduate students and postdoctoral investigators, as well as professionals and academics. It is intended to function as a high-profile and up-to-date reference work on Translational Research in the auditory sciences, emphasizing research programs in the traditional areas including drugs and devices, as well as less traditional, still emerging, areas such as sensorineural hearing loss, auditory processing disorder, cochlear implants and hearing aids, and tinnitus therapies.
Описание: Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Most scientific training programs provide little or no systematic introduction to the issues, challenges, and obstacles that prevent effective research translation, even though these are the key steps that enable high-impact basic science to ultimately result in significant clinical advances that improve patient outcome. This volume will provide an overview of key issues in translation of research from “bedside to bench to bedside”, not only from the perspective of the key funding agencies, but also from the scientists and clinicians who are currently involved in the translational research process. It will attempt to offer insight into real-world experience with intellectual property and technology transfer activities that can help move auditory technologies ahead, as scientists and clinicians typically have little or no formal training in these areas. Translational Research in Audiology and the Hearing Sciences will be aimed at graduate students and postdoctoral investigators, as well as professionals and academics. It is intended to function as a high-profile and up-to-date reference work on Translational Research in the auditory sciences, emphasizing research programs in the traditional areas including drugs and devices, as well as less traditional, still emerging, areas such as sensorineural hearing loss, auditory processing disorder, cochlear implants and hearing aids, and tinnitus therapies.
Автор: Kursad Turksen Название: Cell Biology and Translational Medicine ISBN: 303017588X ISBN-13(EAN): 9783030175887 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions.
This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature's longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas.
This current book is the fifth volume of a continuing series.
Автор: Haighes Edward Название: Translational Studies: Theories and Applications ISBN: 1635497213 ISBN-13(EAN): 9781635497212 Издательство: Неизвестно Цена: 24461.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Translation refers to interpretation of meaning from the original source of communication to the language in which the target audience requires it. Translational studies refer to the practice and application of systematic method of studying, interpreting, describing, localizing, analysing and theorizing texts. It takes elements from other disciplines like computer science, philology, comparative literature, terminology, history, linguistics, philosophy, etc. This book is compiled in such a manner, that it will provide in-depth knowledge about the theory and practice of translational studies. The topics included in it are of utmost significance and are bound to provide incredible insights to readers. This textbook will serve as a reference to a broad spectrum of readers.
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