Reciprocal translation between pathophysiology and practice in health and disease, Soeters, Peter B. (emeritus Professor Of Surgery, Maastricht University Medical Center, Maastricht, The Netherlands) De Leeuw, Peter W. (emeritus Prof
Автор: Mayhan William G. Название: Blood-Brain Barrier in Health and Disease ISBN: 1615047395 ISBN-13(EAN): 9781615047390 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 5016.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The blood-brain barrier (BBB) is a complex and dynamic structure that protects the brain from cells within the vasculature, from the immune system and from pathogens. This barrier is present in arterioles, capillaries and venules and is formed at the level of adjacent endothelial cells, which are coupled to astrocytes, microglia, neurons and pericytes. The structure of this endothelial barrier is unique among endothelia of other organ systems and is composed of complexes made up of tight, gap and adherens junctions. In addition, it is the responsibility of the surrounding cellular elements to maintain the integrity of the junctional complexes and restrict the entry of substances from the blood into the brain. Changes in permeability of the BBB during physiologic and pathophysiologic conditions involve alterations in specific transporters at the level of the endothelium, activation of specific cellular second messenger pathways and/or the dissolution of the junctional complexes composing the BBB. This book focuses on various aspects that account for the formation and maintenance of the BBB, and on disease states that compromise this barrier.
Описание: Specifically designed for future health care providers who will diagnose, manage, and prescribe. Focusing on practical applications of physiology, this book facilitates in-depth understanding of pathophysiological concepts as they relate to disorders commonly seen in practice and includes comprehensive pediatric and geriatric considerations.
Автор: Giuseppe Di Giovanni; Ennio Esposito; Vincenzo Di Название: 5-HT2C Receptors in the Pathophysiology of CNS Disease ISBN: 1617797200 ISBN-13(EAN): 9781617797200 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Increased understanding of the 5-HT2c receptor may play a key role in the treatment of many central nervous system diseases ranging from eating disorders and Parkinson`s to Alzheimer`s and epilepsy. This is the first ever overview of 5-HT2c receptor research.
Автор: Christopher G. Kevil, Shyamal C. Bir, Christopher B. Pattillo Название: Peripheral Arterial Disease: Pathophysiology and Therapeutics ISBN: 1615045988 ISBN-13(EAN): 9781615045983 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 9286.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Peripheral arterial disease (PAD) is a cardiovascular disorder of the peripheral vasculature due to progressive atherosclerotic stenosis of conduit arteries restricting blood flow to tissues. PAD is typically a disease of older individuals. This title discusses PAD signs and symptoms, pathophysiological mechanisms, current management, and future disease targets and possible therapeutic treatments.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
