This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Jan Je?ek; Jan Hlav??ek; Jaroslav ?ebest?k Название: Biomedical Applications of Acridines ISBN: 3319639528 ISBN-13(EAN): 9783319639529 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer`s disease, Parkinson`s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine.
Автор: D. Shi Название: Biomedical Devices and Their Applications ISBN: 3642060684 ISBN-13(EAN): 9783642060687 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Rai Название: Biomedical Applications of Metals ISBN: 3319748130 ISBN-13(EAN): 9783319748139 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: while Section II includes topics on metals toxicity including heavy metals, carcinogens, cancer therapy, Bhasma`s and chelating agents used in Ayurveda, and biochemical and molecular targets including actions of metals.
Описание: Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. . Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies.
Автор: Jana Sougata, Jana Subrata Название: Interpenetrating Polymer Network: Biomedical Applications ISBN: 981150282X ISBN-13(EAN): 9789811502828 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book focuses on novel interpenetrating polymer network (IPN)/semi-IPN technologies for drug delivery and biomedical applications. It also discusses applications of IPN systems in cancer therapy and tissue engineering, and describes the various IPN systems and their wide usage and applications in drug delivery.
Название: Biomedical Applications of Microencapsulation ISBN: 0367201038 ISBN-13(EAN): 9780367201036 Издательство: Taylor&Francis Рейтинг: Цена: 16843.00 р. Наличие на складе: Поставка под заказ.
Описание: "ANOTHER galaxy, another time." This was the opening line for Star Wars: From the Adventures of Luke Skywalker, first published in December 1976, six months before the movie release of Star Wars: A New Hope. This novelization was ghostwritten by Alan Dean Foster but credited to George Lucas. The book title would later be republished under the title Star Wars: A New Hope. This double-sided tee has the first edition cover art by artist Ralph McQuarrie on the front and the book description on the back. Product Details: 100% Cotton fitted tee, Distressed, softened print, colour: black. Size: Medium, Length: 28 1/2 inches, Chest: 39 1/2 inches. Each purchase helps to fund literacy programs and book donations to communities in need.
Описание: Key to biomedical innovation is scientific discovery and its translation into marketable products. This book addresses the link between life sciences discoveries and their dependence on the investor-driven market system through in-depth considerations of the challenges that both scientists and managers must face in the pharmaceutical and medical device industries.
Автор: Jan Je?ek; Jan Hlav??ek; Jaroslav ?ebest?k Название: Biomedical Applications of Acridines ISBN: 3319876805 ISBN-13(EAN): 9783319876801 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Поставка под заказ.
Описание: This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer`s disease, Parkinson`s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine.
Автор: David A. Lane; I. Bj?rk; Ulf Lindahl Название: Heparin and Related Polysaccharides ISBN: 1489924469 ISBN-13(EAN): 9781489924469 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is a record of a meeting entitled "Heparin and Related Polysaccharides" that was held at the Biomedical Center, Uppsala, Sweden between 1-6 September 1991. Altogether, 230 participants from 18 countries attended the meeting, and most were present to be included in a photograph, which is to be found at the end of this volume.
Автор: Mahendra Rai; Avinash P. Ingle; Serenella Medici Название: Biomedical Applications of Metals ISBN: 3030090817 ISBN-13(EAN): 9783030090814 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focused more specifically on the recent advances in applications of various metals and their complexes used in biomedicine, particularly in the diagnosis and treatment of chronic diseases. The editors give equal importance to other key aspects such as toxicological issues and safety concerns. The application of metals in the biomedical field is highly interdisciplinary and has a broad appeal across all biomedical specialties. Biomedical Applications of Metals is particularly focused on covering the role of metals in medicine and the development of novel therapeutic products and solutions in the form of alternative medicines, and some topics on Indian traditional medicine i.e., “Ayurveda”. In Section I, the book discusses the role of metals in medicines and include chapters on nanoparticles, noble metals, medical devices, copper. selenium, silver, and microbial pathogens; while Section II includes topics on metals toxicity including heavy metals, carcinogens, cancer therapy, Bhasma’s and chelating agents used in Ayurveda, and biochemical and molecular targets including actions of metals. These new and emerging concepts of applications of metals in medicine, their crucial role in management of microbial resistance, and their use in the treatment of various chronic diseases is essential information for toxicologists, and clinical and biomedical researchers.
Over the past few decades, there has been unprecedented progress in the design of versatile biopolymer-based nanoplatforms for pharmaceutical and biomedical applications, particularly due to their attractive traits, including excellent biocompatibility, outstanding biodegradability, low immunogenicity, and facile chemical modifiability. Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications serves as a clear and detailed body of information on the synthesis and characterization of biopolymer-based materials in nanomedicine. This book describes various nanomaterials consisting of biopolymers including polysaccharides (i.e., derived from plants, animals, bacteria, algae, and fungi) and polypeptides in terms of their structures, synthetic protocols, and characterization and uses as therapeutic drugs and gene delivery carriers and in other biomedical fields. The chapters of this book, which are contributed by internationally renowned scholars working in the arena of biopolymer-based nanomaterials, would offer a wide vision on the potential future applications of these nanomaterials in the delivery and targeting of bioactive molecules of pharmaceutical interests and in tissue engineering, biosensing, bioimaging, and diagnostic purposes. The state-of-the-art information presented in the book would also encourage young investigators and researchers to further bring cutting-edge developments in the field of nanomedicine in the near future.
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