Colorectal Cancer, An Issue Of Surgical Oncology Clinics,19-4, Guillem, Jose
Автор: Slaby Название: Non-coding RNAs in Colorectal Cancer ISBN: 3319420577 ISBN-13(EAN): 9783319420578 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response. The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology.
Автор: Rodriguez-Bigas Название: Hereditary Colorectal Cancer ISBN: 1441966021 ISBN-13(EAN): 9781441966025 Издательство: Springer Рейтинг: Цена: 44582.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. This is the first book to cover Hereditary nonpolyposis colorectal cancer, also known as the Lynch syndrome, in one comprehensive text.
Описание: Includes topics such as: Overview of Colorectal Cancer Genetics; Familial Adenomatous Polyposis; MYH Associated Polyposis; Other genetic colorectal cancer syndromes; Hereditary Nonpolyposis Colorectal Cancer - emphasis on MSH2/MLH1; Hereditary Nonpolyposis Colorectal Cancer - emphasis on PMS2/MSH6; and, Familial Colorectal Cancer Syndrome Type X.
Описание: Adenocarcinoma is the predominant malignancy found in the colon and rectum. Colorectal cancer is the third most common cancer diagnosed in the developed world with a high incidence of mortality and morbidity. The average five-year survival rate remains poor at 55%, although the development of new drugs has improved the survival rate of colorectal cancer patients. The prognosis of colorectal cancer remains poor in spite of the development of novel therapeutic strategies. Human colorectal cancer represents a heterogeneous group of diseases, and its molecular classification is increasingly important. Characterization of novel biomarker targets may lead to prolong the survival rate of colorectal cancer. Biomarkers may have a potential role in screening, diagnosis, prognosis and monitoring disease. Mutations in the KRAS gene in ~ 40% of tumors have been reported to be induced by genetic and epigenetic alterations. This book, comprised of four chapters, introduces recent topics regarding colorectal cancer, and provides recent highlighted information concerning prevention, diagnosis and treatment. This book will be of interest to undergraduate and graduate students, biomedical researchers, and medical doctors focused on the fields of molecular and cellular biology, medical sciences, and clinical challenges.
Автор: Kim Название: Surgical Treatment of Colorectal Cancer ISBN: 9811338469 ISBN-13(EAN): 9789811338465 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Поставка под заказ.
Описание: This book presents an Asian perspective on how the treatment of colorectal cancer can be optimized and standardized in ways that take into account technological advances and the trend towards individually tailored therapy.
Автор: Giovanni Maria Romano Название: Multimodal Treatment of Recurrent Pelvic Colorectal Cancer ISBN: 8847057663 ISBN-13(EAN): 9788847057661 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book analyzes all aspects of modern multimodal treatment of locally recurrent rectal cancer in the pelvis in order to offer a panoramic overview of the different therapeutic options and enable the reader to balance their benefits and drawbacks. Indications for surgery and the surgical techniques themselves, including reconstruction techniques after major exenterative surgery, are clearly described and evaluated. The role of new imaging tools, such as MRI and PET-CT, in staging recurrences and guiding therapy is assessed and detailed consideration is given to the use of neoadjuvant and iterative radiotherapy and the indications for systemic chemotherapy. Morbidity, mortality, oncologic outcomes, and quality of life issues are carefully analyzed and options for pain control and palliation are examined. Finally, a national survey is presented on the state of the art in the surgical treatment of locally recurrent rectal cancer in Italy. While there has been a dramatic fall in the incidence of local pelvic recurrences, their treatment remains a major clinical challenge which requires a multidisciplinary approach and careful selection of the most appropriate strategy in each case. This book will aid practitioners in making the correct decisions in individual patients.
Автор: Leonard B. Saltz Название: Colorectal Cancer ISBN: 1617377562 ISBN-13(EAN): 9781617377563 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Management options for patients with colorectal cancer have undergone d- matic changes over the past decade. Whereas at the start of 1996 only one drug, 5-Fluorouracil, was available for the treatment of this disease, a mere 10 yr later, six drugs are licensed for use in colorectal cancer, and others are in the late phases of clinical development.
Автор: Correia Название: Colorectal Cancer Liver Metastases ISBN: 3030254852 ISBN-13(EAN): 9783030254858 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Поставка под заказ.
Описание: Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.).
Описание: An issue that deals with the detection and diagnosis of non-polypoid colorectal neoplasms with special emphasis on sessile or flat colon adenoma. It offers information in areas such as Non-Polypoid Colorectal Neoplasms in Ulcerative Colitis, and Detection and Diagnosis of Non-Polypoid Colorectal Neoplasms.
Автор: Kees Welvaart; L.H. Blumgart; J. Kreuning Название: Colorectal Cancer ISBN: 9400991606 ISBN-13(EAN): 9789400991606 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Perhaps the most outstanding new areas discussed and reflected in the proceedings are the possible range and scope of screening techniques, the new possibilities both in treatment and in endoscopic surgery now available as a result of developments in fibre-optic endoscopy, and new approaches and important parameters in staging of the disease.
Описание: Colorectal cancer is one of the most common cancers found in many parts of the world. The challenges and mortality that this disease accompany, call for better and improved methods for patient care and treatment. This book presents the essential work that
Описание: Inflammation and cancer are two major disorders that cause huge concerns in our society. However, what one may not know is that both diseases are closely associated and, in particular, both occur in the gastrointestinal tract and liver. This book describes the mechanics of how inflammation can progress to cancer in these organs.
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