The Handbook of Biomarkers, Kewal K. Jain

Автор: Kyung-Hyun Cho
Название: High-Density Lipoproteins as Biomarkers and Therapeutic Tools
ISBN: 9811373825 ISBN-13(EAN): 9789811373824
Издательство: Springer
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Цена: 27950.00 р.
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Описание: This book is the second of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. In this volume, the focus is on the improvement of HDL, enhancement of its functionality, and the use of HDL for therapeutic purposes. In the first section, up-to-date information is provided on such topics as the tumor regression-promoting and antidiabetic activities of reconstituted HDL containing V156K apolipoprotein A-I, the enhancement of HDL effects by high doses of vitamin C, the benefits derived from incorporation of growth hormones 1 and 2 into rHDL, and the biological functions of omega-3 linolenic acid in rHDL. The enhancement of HDL functionality by policosanol and the resultant benefits are thoroughly examined in a separate section. Readers will also find the latest information on clinical applications of HDL. Here, specific topics include the enhancement of adenoviral gene delivery and the delivery of rapamycin. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

Автор: Alexey Moskalev
Название: Biomarkers of Human Aging
ISBN: 3030249697 ISBN-13(EAN): 9783030249694
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging.In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function).The book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging.Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.

Автор: Kewal K. Jain
Название: The Handbook of Biomarkers
ISBN: 1493974300 ISBN-13(EAN): 9781493974306
Издательство: Springer
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Цена: 34937.00 р.
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Описание: Involved in nearly every therapeutic area, particularly cancer, biomarkers have experienced tremendous advances since the first edition of this book, both in the discovery of biomarkers and in their applications.

Название: Handbook of biomarkers and precision medicine
ISBN: 0367730057 ISBN-13(EAN): 9780367730055
Издательство: Taylor&Francis
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Цена: 11023.00 р.
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Описание: Provides perspective, covers recent developments in technologies that have enabled the expanded use of biomarkers, discusses biomarker characterization and validation, and applications throughout the discovery-development continuum, including Companion Diagnostic ( CDX) development.

Автор: Manuel Men?ndez Gonz?lez
Название: Atlas of Biomarkers for Alzheimer`s Disease
ISBN: 3319079883 ISBN-13(EAN): 9783319079882
Издательство: Springer
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Цена: 13974.00 р.
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Описание: A lot of research on biomarkers for Alzheimer is being done in the last few decades. The aim of these studies is to find some method to ease the diagnosis of Alzheimers as early as possible. Such methods are a range of blood or CSF tests on one hand and several types of neuroimaging scans on the other. Many of the images coming both from laboratory and neuroimaging are very visual and illustrative. These images, accompanied by a short description, can perfectly explain the main results and usefulness of every biomarker. The objective of this book would be to summarize the most important studies made in this field. Few publications have systematically compiled results on this topic and only one as an atlas. Readers would be interested in this publication because it allows reviewing the current status of research by handily visualizing the results.

Автор: Filipe Palavra; Fl?vio Reis; Daniela Marado; Arman
Название: Biomarkers of Cardiometabolic Risk, Inflammation and Disease
ISBN: 3319160176 ISBN-13(EAN): 9783319160177
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This book discusses recent advances in the area of cardiometabolic risk biomarkers of chronic inflammatory and cardiovascular disorders.

Автор: Kyung-Hyun Cho
Название: High-Density Lipoproteins as Biomarkers and Therapeutic Tools
ISBN: 9811373868 ISBN-13(EAN): 9789811373862
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book is the first of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. HDL comprises a diverse group of lipoproteins and its composition and metabolism are dynamic. In this volume, the focus is on the changes observed in HDL under different health statuses, with particular attention to the functional and structural correlations of HDL and apolipoprotein A-1. The impacts of a wide variety of factors on HDL are examined in depth, covering, for example, diet, exercise, smoking, age, diverse diseases, and different forms of environmental pollution. It has long been known that HDL has anti-atherosclerotic and antidiabetic properties, and more recently its anti-aging activities have been recognized. These benefits of HDL are highly dependent on its lipids, proteins, apolipoproteins, and enzymes, and specifically their composition and ratios. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.