Hormones in Ageing and Longevity, Suresh Rattan; Ramesh Sharma
Автор: Suresh Rattan; Ramesh Sharma Название: Hormones in Ageing and Longevity ISBN: 3319630008 ISBN-13(EAN): 9783319630007 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This multi-chapter book focuses on one of the hottest topics in ageing research - the role of hormones in health and longevity, offering a comprehensive and up-to-date overview of their mechanistic roles in health, ageing and longevity.
Автор: Alexander Vaiserman Название: Early Life Origins of Ageing and Longevity ISBN: 3030249573 ISBN-13(EAN): 9783030249571 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a comprehensive overview of the field of developmental programming of ageing phenotypes. Although gerontological research has traditionally focused on later stages of the life cycle, growing evidence indicates that both the rate of ageing-associated functional declines, and the risks of later-life chronic pathological conditions, can be traced to origins early in life. While other books in the field concentrate on the developmental origin of particular disorders, this volume offers a detailed guide to all important aspects of the role of early-life conditions in programming both chronic pathological conditions and the ageing process.Interest in the study of ageing and longevity had its beginnings in research on the fetal origins of adult disease. This has evolved into a hypothesis on the Developmental Origins of Adult Health and Disease (DOHaD), which postulates that adverse environmental exposures during critical in-utero and early postnatal stages of development may permanently change physiological responses and cause functional impairments and disorders in adult life. In this book, the contributing authors and leading experts from around the world, describe research on mechanisms underlying the developmental programming phenomenon, as well as interventional strategies aimed at restoring developmentally disrupted epigenetic patterns. Early Life Origins of Ageing and Longevity benefits a wide audience of working scientists, clinicians, and advanced students, and will also interest scientifically curious general readers who wish to know more about current research in this rapidly evolving field.
Автор: Muсoz-Espin Daniel, DeMaria Marco Название: Senolytics in Disease, Ageing and Longevity ISBN: 3030449025 ISBN-13(EAN): 9783030449025 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers comprehensive information on the new and rapidly evolving science of identifying and targeting senescent cells, and on the exciting prospect of new diagnostic and therapeutic opportunities for stopping, and even reversing, the progression of disease and the deterioration of the human body due to ageing.
Автор: Vaiserman Alexander Название: Early Life Origins of Ageing and Longevity ISBN: 3030249603 ISBN-13(EAN): 9783030249601 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface
SECTION I. OVERVIEW 1. Epidemiology of Early Nutrition and Adult Health: Metabolic Adaptations and Body Composition 2. General Biology of the Developmental Origins of Health SECTION II. EXPERIMENTAL STUDY OF DOHAD 3. Early Life Programming of Aging in Genetically Long-Lived Mice 4. Immunological Basis of In Utero Programming of Adult Disease 5. Early Life Developmental Programming of the GH/IGF Axis and Long-Term Health 6. Early Life Nutritional Programming of Adult Health Status 7. The Interplay between Dopamine and Environment as the Biological Basis for the Early Origins of Mental Health 8. The Developmental Origins of Osteoporosis
9. Nutrigenomics as a Strategy for Neuronal Health
SECTION III. EPIDEMIOLOGICAL EVIDENCE 10.Prenatal Undernutrition and Ageing and Longevity '11. Influence of Maternal Obesity on the Long-Term Health of Offspring 12. Prenatal Exposure to Famine and Ageing 13. Why is Parental Lifespan Linked to Children's Chances of Reaching a High Age? A Transgenerational Hypothesis 14.Early-Life Adjustment of Epigenetic Aging Clock
SECTION IV. PERSPECTIVES AND IMPLICATIONS 15. Public Health and Social Policy Perspectives on DOHaD
Index
Автор: Lopez-Otin, Carlos Название: Mitochondria and Longevity ISBN: 0128157364 ISBN-13(EAN): 9780128157367 Издательство: Elsevier Science Рейтинг: Цена: 27791.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mitochondria and Longevity, Volume 340, the latest release in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics with this release focusing on topics such as Mitochondria metabolism and aging, Mitohormesis, Mitochondrial dynamics in the aging stem cell compartment, Mitochondrial proteostasis and aging, Mitochondrial DNA mutations and aging, Mitochondrial sirtuins, NAD+, NADH and aging, Mitophagy and aging, Mitochondria, calcium transport and aging.
Автор: J.R. Carey; Jean-Marie Robine; J.-P. Michel Название: Longevity and Frailty ISBN: 3642064299 ISBN-13(EAN): 9783642064296 Издательство: Springer Рейтинг: Цена: 33401.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Understanding the relationship between frailty and longevity becomes increasingly important as the world continues to age and life expectancy in most countries continues to increase.
Автор: Jacqueline L. Angel; Fernando Torres-Gil; Kyriakos Название: Aging, Health, and Longevity in the Mexican-Origin Population ISBN: 148999792X ISBN-13(EAN): 9781489997920 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aging, Health, and Longevity in the Mexican-Origin Population creates a foundation for an interdisciplinary discussion of the trajectory of disability and long-term care for older people of Mexican-origin from a bi-national perspective.
Автор: Arthur V. Everitt; Suresh I. S. Rattan; David G. C Название: Calorie Restriction, Aging and Longevity ISBN: 9400791151 ISBN-13(EAN): 9789400791152 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Long-term reduction in calorie intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer. This book provides the latest information on the beneficial effects of calorie restriction on health and life-span.
Автор: Moskalev, Alexey Название: Epigenetics of Aging and Longevity ISBN: 0128110600 ISBN-13(EAN): 9780128110607 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Поставка под заказ.
Описание:
Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses--including cancer and cardiovascular, metabolic, and neurodegenerative diseases--are explored in detail.
This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease.
Автор: Caleb E. Finch; Jean-Marie Robine Название: Brain and Longevity ISBN: 3642639488 ISBN-13(EAN): 9783642639487 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this third volume on longevity Fondation Ipsen has again collected the most recent results in research on genes and diet in the evolution of human longevity, educational level and longevity, cognitive impairment and survival at older age and other contributions.
Автор: Marco Malavolta; Eugenio Mocchegiani Название: Trace Elements and Minerals in Health and Longevity ISBN: 303003741X ISBN-13(EAN): 9783030037413 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, ande) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.
Автор: Avril Woodhead Название: Evolution of Longevity in Animals ISBN: 1461290775 ISBN-13(EAN): 9781461290773 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The analysis of intra-group correlations between LS and BW at representative intervals yields no consistent support for the hypothesis that lower BW is associated with longer LS. However, when BW at absolute ages were correlated with LS, support for the positive relationship between BW and LS was not as forthcoming.
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