Resistance to Molecular Therapies for Hepatocellular Carcinoma, Augusto Villanueva
Автор: Rajagopal N. Aravalli; Clifford J. Steer Название: Hepatocellular Carcinoma ISBN: 3319094130 ISBN-13(EAN): 9783319094137 Издательство: Springer Рейтинг: Цена: 9141.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides up-to-date information on the development and progression of hepatocellular carcinoma (HCC) with a review of the cellular and molecular mechanisms involved in the disease process.
Автор: Tim F. Greten Название: Immunotherapy of Hepatocellular Carcinoma ISBN: 3319649574 ISBN-13(EAN): 9783319649573 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma.
Автор: Augusto Villanueva Название: Resistance to Molecular Therapies for Hepatocellular Carcinoma ISBN: 3319561960 ISBN-13(EAN): 9783319561967 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance;
Автор: Brian I. Carr Название: Hepatocellular Carcinoma ISBN: 3319817051 ISBN-13(EAN): 9783319817057 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
•Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. However, the increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology are changing. During this exciting time in the field of HCC basic science and clinical management, many changes are simultaneously occurring at multiple levels of our understanding and management of the disease. Suddenly, there are several new choices of therapy to offer patients. Hepatocellular Carcinoma, 3rd edition addresses this fast-changing disease and gives the reader a clearer understanding of the many mechanisms involved in carcinogenesis of the liver. This comprehensive and detailed review of how to diagnose and treat hepatocellular carcinoma is written by international leaders in the field, covering both clinical treatment choices and the basic science underlying HCC development. Updated and enhanced from the last edition in 2009, Hepatocellular Carcinoma, 3rd edition features 12 new chapters including discussion of molecular markers, molecular hepatocarcinogenesis, microenvironment, heterogeneity, the new and exciting contributions of immunotherapy, and updates on the major effective hepatitis therapies that will transform HCC incidence and perhaps also the therapy. This cutting-edge text is a vital resource and must-have for today’s hepatologists and medical and surgical oncologists.
'This is a well written text and should be a good reference book for those who see patients with HCC..' - Practical Gastroenterology
'...a useful tool for both physicians and surgeons with a specific interest in the management of patients with HCC.' - Digestive and Liver Disease
Автор: Jean-Nicolas` Vauthey; Antoine Brouquet Название: Multidisciplinary Treatment of Hepatocellular Carcinoma ISBN: 3642445918 ISBN-13(EAN): 9783642445910 Издательство: Springer Рейтинг: Цена: 29209.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this textbook, experts in the field of hepatocellular carcinoma present and discuss the various strategies employed in the treatment of the disease. Up-to-date information is provided on the indications for and outcome of a range of treatment options.
Автор: Haeryoung Kim Название: Atlas of Hepatocellular Carcinoma Pathology ISBN: 9811684995 ISBN-13(EAN): 9789811684999 Издательство: Springer Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This atlas is designed to be a user-friendly bench-side reference for pathology trainees and general pathologists in handling and interpreting specimens of hepatocellular carcinoma. It provides over 550 high-quality gross and microscopic photos focusing on hepatocellular carcinoma and its mimickers, and demonstrating a full range of various histological variants of hepatocellular carcinoma. Introductory text in each chapter summarises salient clinical associations, pathological features, and molecular alterations of different variants of hepatocellular carcinoma. Differentiation between hepatocellular carcinoma and its mimickers is illustrated through various case studies. The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high. The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.
Описание: The story of the doomed love affair between Kitty Jewell and Prince Lobengula, a heart-breaking tale, a real mystery, and a window into Victorian attitudes to race, the beginnings of tabloid journalism, and feminism in the 1890s - in short, a true story that has everything. A documentary on mixed marriages - on the story of Kitty and the Prince - is to be shown on Channel 4 to coincide with publication.
Описание: Updates one of the most highly requested topics in liver disease by inviting highly distinguished authors to address the important aspects of diagnosis and treatment of hepatocelluar carcinoma. This book addresses various issues, including the role of oncogenic viruses, molecular and genetic guidelines, and screening and staging.
Автор: Hoshida Название: Hepatocellular Carcinoma ISBN: 3030215393 ISBN-13(EAN): 9783030215392 Издательство: Springer Рейтинг: Цена: 11878.00 р. Наличие на складе: Поставка под заказ.
Описание: Theologies on the Move examines how the experiences of migration and pilgrimage that are created as a result of the pressures of neoliberal capitalism shape theological and religious traditions. Based on these insights, the contributors examine what difference religion can make in a world dominated by the interests of the few rather than the many.
Автор: Hart Evangeline Название: Hepatocellular Carcinoma: Clinical Oncology ISBN: 1632428954 ISBN-13(EAN): 9781632428950 Издательство: Неизвестно Рейтинг: Цена: 24461.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Hepatocellular carcinoma (HCC) is the most common liver cancer occurring in adults. It is also the leading cause of deaths in patients with liver cirrhosis. Some of the risk factors for this condition are exposure to alcohol or aflatoxin, hepatitis infection, alpha 1-antitrypsin deficiency, hemochromatosis, NASH, metabolic syndrome, etc. HCC may present symptoms such as abdominal swelling due to fluid buildup in the abdominal cavity, yellow skin, loss of appetite, easy bruising, nausea, vomiting, etc. HCC is generally diagnosed at an advanced stage and is thus associated with a high rate of mortality. CT scan, MRI and ultrasound are ideal for liver analysis and detection of HCC. The treatment of HCC is based on a review of the stage of the disease, availability of liver transplant and a person's likelihood of tolerating surgery. Accordingly, a patient may be recommended for a partial hepatectomy, orthotopic liver transplantation, targeted therapies, loco-regional therapy, etc. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in the field of clinical oncology. It discusses the fundamentals as well as modern approaches in the diagnosis and treatment of this cancer. This book aims to serve as a resource guide for students and experts alike and contribute to the growth of the discipline.
The liver has an important role in nutritional homeostasis, and it is well known that liver diseases can lead to abnormalities in the nutrient metabolism and to subsequent malnutrition. Because malnutrition is particularly prevalent in patients with liver cirrhosis, proper nutritional assessment and support for cirrhotic patients is essential. This collection of research and clinical findings on nonalcoholic steatohepatitis (NASH) and nutritional therapy contains significant new findings in several fields. As NASH frequently causes liver cirrhosis, the nutritional aspects of its treatment are discussed. Other areas covered include nonalcoholic fatty liver, the role of leptin in the pathogenesis of NASH, restricted diets and exercise therapy, mammalian targets of the peptide rapamycin, and genetic factors influencing the development of NASH. This book is intended to be of particular relevance to researchers and those practicing in the field.
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