Автор: Gilles Goetz Название: Cyclic Peptide Design ISBN: 1493995030 ISBN-13(EAN): 9781493995035 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers strategies to improve cell permeability, intestinal permeability, and metabolic stability, which are the typical liabilities associated with cyclic peptides, to enhance protein-protein recognition, and to build upon nature’s cyclic peptides and macrocycles. Chapters also cover key peptide screening and display strategies, as well as important synthetic approaches towards cyclic and helical peptides. Cyclic peptides have become of significant importance as chemical tools in biology and drug discovery, since this class of chemicals has become a credible alternative source of new drug leads on par with traditional small molecules. As a part of the Methods in Molecular Biology series, this collection includes the kind of detail and implementation advice to aid researchers in the field.
Authoritative and cutting-edge, Cyclic Peptide Design serves as a critical resource and go-to reference for researchers within the pharmaceutical industry, as well as scientists and students in the bioorganic, medicinal, and natural product chemistry fields.
Описание: Poisonous mushrooms have fascinated scientists and laypersons alike for thousands of years. Almost all mushroom fatalities are due to the genus Amanita, whose poetic common names (death cap, destroying angel) attest to their lethality. In his classic 1986 book, Theodor Wieland covered the state of our knowledge about the chemistry and biochemistry of the toxins of Amanita mushrooms up until that time, with a particular focus on the decades of chemical research by him and the Wieland dynasty (including his father, brother, brother-in-law, and cousin). Wieland’s book is now mainly of historical interest, with its exhaustive overview of the early chemical studies done without benefit of methods taken for granted by modern chemists.
This book is a complete top-to-bottom revision of Wieland’s 1986 book. The material covers history, chemistry, and biology with equal thoroughness. It should be of interest to natural products chemists and biologists, professional and amateur mycologists, and toxicologists.
The three scientific fields that are most relevant to the book are natural products chemistry, mycology, and fungal molecular genetics. Dr. Walton is an expert in all three. To maximize the broad utility and appeal of the book, care has been taken to define all technical terms specific to a particular discipline, so that, for example, mycologists will be able to understand the relevant chemistry, and chemists will be able to understand the relevant fungal biology.
Название: Cyclic Peptides: From Bioorganic Synthesis to Applications ISBN: 1782625283 ISBN-13(EAN): 9781782625285 Издательство: Royal Society of Chemistry Рейтинг: Цена: 35693.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.
Автор: Peter E Nielsen; Daniel H. Appella Название: Peptide Nucleic Acids ISBN: 1627035524 ISBN-13(EAN): 9781627035521 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume details methods and protocols in PNA chemistry. It features step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Описание: Illustrated throughout with successful case studies, this book provides a holistic, cutting-edge view of the subject area and is ideal for chemical biologists and medicinal chemists interested in developing PPI inhibitors.
Автор: Laszlo Otvos Название: Peptide-Based Drug Design ISBN: 1617378690 ISBN-13(EAN): 9781617378690 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Due to their high specificity and low toxicity profile, peptides are once more central to the development of new drugs. Comprehensive and up-to-date, this practical volume provides scientists with a clear, concise guide for continuing this vital research.
Описание: This book provides summarized methods for the preparation, purification of modified peptides, and assessment of their biochemical activities. It features step-by-step detail essential for reproducible results and expert implementation advice.
Автор: Chris Van Der Walle Название: Peptide and Protein Delivery, ISBN: 0123849357 ISBN-13(EAN): 9780123849359 Издательство: Elsevier Science Рейтинг: Цена: 20379.00 р. Наличие на складе: Поставка под заказ.
Описание: The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. This title addresses the routes for delivery of therapeutics. It covers cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery.
Автор: Harm-Anton Klok; L. Ayres; Helmut Schlaad; T. Demi Название: Peptide Hybrid Polymers ISBN: 3642068979 ISBN-13(EAN): 9783642068973 Издательство: Springer Рейтинг: Цена: 40389.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1 T.J. Deming: Polypeptide and Polypeptide Hybrid Copolymer Synthesis via NCA Polymerization.- D.W.P.M. Lцwik, L. Ayres, J.M. Smeenk, J.C.M. van Hest: Synthesis of Bio-inspired Hybrid Polymers Using Peptide Synthesis and Protein Engineering.- 3 H. Schlaad: Solution Properties of Polypeptide-Based Copolymers.- 4 H.-A. Klok, S. Lecommandoux: Solid State Structure, Organization and Properties of Peptide -Synthetic Hybrid Block Copolymers.- 5 K. Osada, K. Kataoka: Drug and Gene Delivery Based on Supramolecular Assembly of PEG-Polypeptide Hybrid Block Copolymers.-
Автор: Michael B. Sporn; Anita B. Roberts Название: Peptide Growth Factors and Their Receptors II ISBN: 3642747833 ISBN-13(EAN): 9783642747830 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Название: Peptide synthesis and applications ISBN: 1627035435 ISBN-13(EAN): 9781627035439 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Using a broad range of methods and strategies, this essential resource will aid scientists in understanding different approaches to the synthesis of peptides. It features step-by-step, readily reproducible laboratory protocols and key implementation advice.
Автор: Gregg B. Fields Название: Peptide Characterization and Application Protocols ISBN: 161737637X ISBN-13(EAN): 9781617376375 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is dedicated to the characterization of peptides and their applications for the study of biochemical systems. Part II, Application, presents a variety of specific applications for synthetic peptides. This book is an indispensable aid in the pursuit of new directions in peptide research.
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