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RNA Interference and CRISPR Technologies, Mouldy Sioud


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Автор: Mouldy Sioud
Название:  RNA Interference and CRISPR Technologies
ISBN: 9781071602898
Издательство: Springer
Классификация:

ISBN-10: 1071602896
Обложка/Формат: Hardcover
Страницы: 486
Вес: 1.16 кг.
Дата издания: 2020
Серия: Methods in Molecular Biology
Язык: English
Издание: 1st ed. 2020
Иллюстрации: 47 tables, color; 48 illustrations, color; 22 illustrations, black and white; xvi, 486 p. 70 illus., 48 illus. in color.
Размер: 25.65 x 19.30 x 3.05 cm
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Подзаголовок: Technical Advances and New Therapeutic Opportunities
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This volume explores the uses of RNAi and CRISPR interferences as a general method for inhibiting gene expression, with focus on their biological functions, design, chemical modifications, delivery, and preclinical/clinical applications. In addition to relevant backgrounds, the chapters in this book discuss simple and accurate protocols dealing with the latest advances in RNAi and CRISPR applications and look at how these methods differ from one another. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, RNA Interference and CRISPR Technologies: Technical Advances and New Therapeutic Opportunities is a valuable resource for any scientist, teachers, graduate student, postdoc, and clinician interested in this field. This book also benefits anyone in research and development in biotech and pharmaceutical companies who want to understand more about these technologies, and their applications in biology and medicine.
Дополнительное описание: RNA and CRISPR Interferences: Past, Present and Future Perspectives.- Chemical Modifications in RNA Interference and CRISPR/Cas Genome Editing Reagents.- Preparation, Determination of Activity, and Biodistribution of Cholesterol-Containing Nuclease-Resist



RNA Interference

Автор: Mouldy Sioud
Название: RNA Interference
ISBN: 1493915371 ISBN-13(EAN): 9781493915378
Издательство: Springer
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Цена: 22359.00 р.
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Описание: RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA`s unwanted effects.

RNA Interference and Cancer Therapy

Автор: Lekha Dinesh Kumar
Название: RNA Interference and Cancer Therapy
ISBN: 1493992198 ISBN-13(EAN): 9781493992195
Издательство: Springer
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Цена: 15372.00 р.
Наличие на складе: Поставка под заказ.

Описание: This comprehensive volume collects a repertoire of techniques for the adoption and exploitation of RNA interference (RNAi) as a fertile strategy to develop the bio-drugs of future in the vital field of cancer research. Exploring the immense ‘bench to bedside’ potential of RNAi as a therapeutic molecule, the book focuses many of its chapters on nanoparticle-based targeted deliveries, including aptamers, as well as techniques for using RNAi technology to combat various cancers in preclinical studies. Each of the 26 chapters is authored by the pioneers in the respective areas and thus provides a practical and empirical account of the techniques that could be used as benchmark tools in the area of cancer research. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and essential, RNA Interference and Cancer Therapy: Methods and Protocols provides the necessary guidance for both novice and professional researchers who intend to discover and innovate newer means of using RNAi technology to combat cancer, one of the greatest scourges of human health.
CRISPR Gene Editing

Автор: Yonglun Luo
Название: CRISPR Gene Editing
ISBN: 1493991698 ISBN-13(EAN): 9781493991693
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This detailed volume guides readers through strategic planning and user-friendly guidelines in order to select the most suitable CRISPR-Cas system and target sites with high activity and specificity. Methods covering CRISPR gRNA design, CRISPR delivery, CRISPR activity quantification (indel quantification), and examples of applying CRISPR gene editing in human pluripotent stem cells, primary cells, gene therapy, and genetic screening are included. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and invaluable, CRISPR Gene Editing: Methods and Protocols will assist undergraduates, graduates, and researchers with detailed guidelines and methods for the vitally important CRISPR gene editing field.
Chapter 3 is available open access under a CC BY 4.0 license via link.springer.com.
MicroRNA Interference Technologies

Автор: Zhiguo Wang
Название: MicroRNA Interference Technologies
ISBN: 3642101518 ISBN-13(EAN): 9783642101519
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book presents an overview of up-to-date knowledge of MicroRNAs (miRNAs) biology and their potential as therapeutic targets for human disease. It also gives an introduction of the new concept of miRNA interference (miRNAi).

RNA Interference

Автор: Patrick J. Paddison; Peter K. Vogt
Название: RNA Interference
ISBN: 3642444458 ISBN-13(EAN): 9783642444456
Издательство: Springer
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Цена: 21661.00 р.
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Описание: In the last few years the major effect that RNAi has had in invertebrate systems like C.elegans and drosophila is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. In the next decade, there will no doubt be both notable successes and failures as we attempt to apply this genetic tool to various biological problems for the first time in academia and industry. Through the introduction of RNAi, mammalian systems have finally gained admittance to the pantheon of model genetic systems.

RNA Interference Techniques

Автор: Scott Q. Harper
Название: RNA Interference Techniques
ISBN: 1493957627 ISBN-13(EAN): 9781493957620
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This book presents methods for design and delivery of artificial inhibitory RNAs to neural tissue and for detecting or cloning endogenous microRNAs, used in research and in development of therapeutics for dominant genetic disorders, cancer, or viral infection.

RNA Interference Technology

Автор: Appasani
Название: RNA Interference Technology
ISBN: 0521205174 ISBN-13(EAN): 9780521205177
Издательство: Cambridge Academ
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Цена: 8870.00 р.
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Описание: RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. In this overview, the basic concepts of RNAi biology are discussed, as well as the current and potential applications, providing an invaluable reference for all those who need to understand this emerging technology.

Rna interference

Название: Rna interference
ISBN: 3540751564 ISBN-13(EAN): 9783540751564
Издательство: Springer
Рейтинг:
Цена: 28734.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In the last few years the major effect that RNAi has had in invertebrate systems is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. Through the introduction of RNAi, mammalian systems have finally gained admittance to the pantheon of model genetic systems.

RNA Interference

Автор: Mouldy Sioud
Название: RNA Interference
ISBN: 1493948911 ISBN-13(EAN): 9781493948918
Издательство: Springer
Рейтинг:
Цена: 15372.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA`s unwanted effects.

Crispr Guide RNA Design: Methods and Protocols

Автор: Fulga Tudor A., Knapp David J. H. F., Ferry Quentin R. V.
Название: Crispr Guide RNA Design: Methods and Protocols
ISBN: 1071606867 ISBN-13(EAN): 9781071606865
Издательство: Springer
Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Beginning with a section on computational design of target-specific guide RNAs, the book continues by covering chemical modifications to alter guide RNA stability, specificity, and efficiency, as well as to create inducible guide RNAs, append additional functional domains, and express guide RNAs in a conditional manner.

Precision Medicine, CRISPR, and Genome Engineering

Автор: Stephen Tsang; George M. Church
Название: Precision Medicine, CRISPR, and Genome Engineering
ISBN: 331963903X ISBN-13(EAN): 9783319639031
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine.

Precision Medicine, Crispr, and Genome Engineering: Moving from Association to Biology and Therapeutics

Автор: Tsang Stephen H.
Название: Precision Medicine, Crispr, and Genome Engineering: Moving from Association to Biology and Therapeutics
ISBN: 3319876678 ISBN-13(EAN): 9783319876672
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians.


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