Автор: Ralph A. Bradshaw Название: Regulation of Organelle and Cell Compartment Signaling, ISBN: 0123822130 ISBN-13(EAN): 9780123822130 Издательство: Elsevier Science Рейтинг: Цена: 9767.00 р. Наличие на складе: Нет в наличии.
Описание: Suitable for researchers across molecular biology, biochemistry, cell biology and genetics, this title includes articles that emphasize signaling to and from intracellular compartments including transcriptional responses to cytoplasmic and nuclear signaling events, chromatin remodeling and stress responses, and more.
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Описание: This volume presents a unique comparative treatment of the role oxidative stress plays in vertebrates and invertebrates in multiple organ systems with regards to cell death, development, aging, and human diseases, and anti-oxidant therapy.
Автор: David G. Lambert Название: Calcium Signaling Protocols ISBN: 161737573X ISBN-13(EAN): 9781617375736 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the first edition of Calcium Signaling Protocols I began by writing "The regula- 2+ tion of intracellular Ca is a common theme presented in many papers over the last 20 2+ or so years and the description of the Ca -sensitive indicator dye fura-2 in 1985 resulted in a massive increase in these types of studies.
Автор: Rakesh Srivastava Название: Apoptosis, Cell Signaling, and Human Diseases ISBN: 1617377139 ISBN-13(EAN): 9781617377136 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These volumes present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways.
Автор: Xuemin Wang Название: Phospholipases in Plant Signaling ISBN: 3662510294 ISBN-13(EAN): 9783662510292 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: PART I: Plant Phospholipase Families and Derived Messengers.- PLD: Phospholipase D and Phosphatidic Acid.- PI-PLC: Phosphoinositide-phospholipase Cs in Plant Signalling.- NPC: Non-specific Phospholipase Cs in Plant Functions.- pPLA: Patatin-Containing Phospholipase A in Plant Signalling.- sPLA2 and PLA1: Phospholipase A2 and Phospholipase A1 in Plant Signalling.- Biophysical Properties of Lipid Mediators and the Effects on Molecular Interactions.- PART II: Phospholipase Signalling in Response to Environmental Stresses.- Phospholipases in Plant Response to Reactive Oxygen Species and Hyperosmotic Stress.- Phospholipase Ds in Plant Response to Hyperosmotic Stresses.- Phospholipases in Plant Response to Nitrogen and Phosphorus Status.- PART III: Phospholipases in Plant Biotic Interactions.- Lipases in Signalling Plant Defense Responses.- Phospholipase A in Plant Immunity.- Phospholipases in Regulating Plant-herbivore Interaction.- PART IV: Phospholipases in Plant Growth and Development.- Phospholipases in Cytoskeleton Dynamics and Plant Growth.- Phospholipases and Lipid Signalling in Cytoskeleton and Pollen Tube Growth.- Phospholipases and Lipid Signalling in Secretory Pathways.- Phospholipase A in Carbon Partitioning and Anisotropic Plant Cell Growth.
Автор: Xuedong Liu; Meredith D. Betterton Название: Computational Modeling of Signaling Networks ISBN: 1493958437 ISBN-13(EAN): 9781493958436 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focusing on Systems of ODEs, parameterization of signaling models, signaling pathways, mass-action kinetics and ODEs and how to use modeling to plan experiments, this Methods in Molecular Biology (TM) book details steps for getting optimal laboratory results.
Автор: Khalid Rehman Hakeem; Reiaz Ul Rehman; Inayatullah Название: Plant signaling: Understanding the molecular crosstalk ISBN: 8132234790 ISBN-13(EAN): 9788132234791 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: ГЇВїВЅ Plant signalling has emerged as an integrated field which has become indispensable in recent times to study any biological process. It is now possible to view the different information`s in a systems biology approach which has unravelled the association/ new processes and thus helped us enormously in understanding of the biological processes.
Автор: Alfred Wittinghofer Название: Ras Superfamily Small G Proteins: Biology and Mechanisms 1 ISBN: 370911988X ISBN-13(EAN): 9783709119884 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The focus of this first volume is on the Rho and Ras subfamily of small G proteins.Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease.
Автор: Daniel Johnson Название: Cell Death Signaling in Cancer Biology and Treatment ISBN: 1493901079 ISBN-13(EAN): 9781493901074 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Discussing both preclinical and clinical approaches to targeted attacks on tumor cells, this is a key contribution to the fight against cancer, sharing cutting-edge research on the molecular and biological processes regulating cell death in malignant tumors.
Автор: Jos? Mar?n-Garc?a Название: Signaling in the Heart ISBN: 1489995765 ISBN-13(EAN): 9781489995766 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.
Автор: Wen-Xing Ding; Xiao-Ming Yin Название: Molecules, Systems and Signaling in Liver Injury ISBN: 3319581058 ISBN-13(EAN): 9783319581057 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This essential volume presents comprehensive information on cell death and autophagy in liver diseases, including the role and molecular signaling pathways of cell death in alcohol and non-alcoholic fatty liver disease, bile acids, hepatitis C virus and drug-induced liver injury.
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