Автор: Christine S. Walsh Название: Clinical Trials in Ovarian Cancer ISBN: 081358647X ISBN-13(EAN): 9780813586472 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 18810.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: When a patient is diagnosed with a gynecological malignancy, she and her doctors must make urgent, high-risk decisions about her course of treatment. In selecting an appropriate plan of care, physicians must weigh the patient's individual needs, the tumor's specific characteristics, and the treatment's potential side effects. Because there is no one-size-fits-all treatment solution, a plethora of clinical trials have been performed on ovarian cancer patients, but clinicians may struggle to keep up with this ever-growing body of research. Collecting and synthesizing research findings from a wide array of medical journal articles and book chapters, Clinical Trials in Ovarian Cancer provides physicians with an invaluable resource. Gynecologic oncologist Christine S. Walsh systematically outlines each of the seminal Phase III trials that have shaped the treatment of ovarian cancers, detailing the rationale for the trial, the patient population studied, treatment delivery methods, efficacy, toxicity, and trial conclusions. She provides a clear overview of established treatments, as well as still-controversial experimental approaches. The first book to organize this cutting-edge research into an easy-to-use reference, Clinical Trials in Ovarian Cancer should help medical personnel at all levels provide their patients with the highest standard of care.
Автор: Yajnik, Santosh Название: Landmark trials in oncology ISBN: 3030144046 ISBN-13(EAN): 9783030144043 Издательство: Springer Рейтинг: Цена: 12577.00 р. Наличие на складе: Поставка под заказ.
Описание: This book describes the evolution of treatment in oncology through the lens of approximately 250 landmark clinical trials. Such major clinical trials for common malignancies including breast, prostate, lung, gastrointestinal, genitourinary, and gynecologic cancers are discussed.
Название: Cancer Clinical Trials ISBN: 1498706886 ISBN-13(EAN): 9781498706889 Издательство: Taylor&Francis Рейтинг: Цена: 14086.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis provides statisticians with an understanding of the critical challenges currently encountered in oncology trials. Well-known statisticians from academic institutions, regulatory and government agencies (such as the U.S. FDA and National Cancer Institute), and the pharmaceutical industry share their extensive experiences in cancer clinical trials and present examples taken from actual trials.
The book covers topics that are often perplexing and sometimes controversial in cancer clinical trials. Most of the issues addressed are also important for clinical trials in other settings. After discussing general topics, the book focuses on aspects of early and late phase clinical trials. It also explores personalized medicine, including biomarker-based clinical trials, adaptive clinical trial designs, and dynamic treatment regimes.
Автор: William Kevin Kelly, Susan Halabi Название: Oncology Clinical Trials: Successful Design, Conduct, and Analysis ISBN: 0826168728 ISBN-13(EAN): 9780826168726 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 23199.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The second edition of Oncology Clinical Trials has been thoroughly revised and updated and now contains the latest designs and methods of conducting and analyzing cancer clinical trials in the era of precision medicine with biologic agents—including trials investigating the safety and efficacy of targeted therapies, immunotherapies, and combination therapies as well as novel radiation therapy modalities. Now divided into five sections this revamped book provides the necessary background and expert guidance from the principles governing oncology clinical trials to the innovative statistical design methods permeating the field; from conducting trials in a safe and effective manner, analyzing and interpreting the data, to a forward-looking assessment and discussion of regulatory issues impacting domestic, international, and global clinical trials.Considered by many as the gold standard reference on oncology clinical trials in the field, the second edition continues to provide examples of real-life flaws and real-world examples for how to successfully design, conduct and analyze quality clinical trials and interpret them. With chapters written by oncologists, researchers, biostatisticians, clinical research administrators, and industry and FDA representatives, this volume provides a comprehensive guide in the design, conduct, monitoring, analysis, and reporting of clinical trials in oncology.New to this Edition:Outlines how to design clinical trials with and without biomarker testing—including genomics-based “basket” trials, and adaptive trials for all phases during treatment and quality-of-life trialsIncludes new chapters on immunotherapy trials, radiation therapy trials, multi-arm trials, meta-analysis and adaptive design, use of genomics, dose modifications and use of ancillary treatments in investigational studies, establishing surrogate endpoints, practical issues with correlative studies, cost-effectiveness analysis, and moreComprehensively covers all regulatory aspects in the pursuit of global oncology trialsDigital Access to the eBook included
Автор: Susan Halabi, Stefan Michiels Название: Textbook of Clinical Trials in Oncology: A Statistical Perspective ISBN: 1138083771 ISBN-13(EAN): 9781138083776 Издательство: Taylor&Francis Рейтинг: Цена: 22202.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is a textbook on the design and analysis of cancer clinical trials. It opens with a discussion of the choice of endpoints before moving onto discuss various types of trials across all phases of study, including basket trials, non-inferiority trials and multi-arm trials.
Описание: Reviews the important clinical trials in following topics: breast cancer, soft tissue sarcoma, rectal and anal carcinoma, pancreatic adenocarcinoma, hepatocellular carcinoma, gastric cancer, esophageal cancer, colon cancer, advanced and metastatic colorectal carcinoma, gastrointestinal stromal tumors, and melanoma.
Описание: This book provides statisticians with an understanding of the critical challenges currently encountered in oncology trials. The book covers state-of-the-art approaches to the design and analysis of cancer clinical trials, such as adaptive designs, biomarker-based trials, and dynamic treatment regimes.
Автор: Renz, Malte Diver, Elisabeth Growdon, Whitfield Dorigo, Oliver Название: Synopsis of key gynecologic oncology trials ISBN: 0367190680 ISBN-13(EAN): 9780367190682 Издательство: Taylor&Francis Рейтинг: Цена: 7501.00 р. Наличие на складе: Поставка под заказ.
Описание:
This text is a fast and convenient overview of the clinical trials in gynecologic cancer treatment, setting out the evidence base of treatment decisions in uterine, ovarian, cervical and vulval cancers and gestational trophoblastic neoplasia. Residents and fellows will find this book an indispensable reference for revision, while existing practitioners will welcome it as a clarification of the evidence base for treatment options.
Автор: Halabi Susan, Michiels Stefan Название: Textbook of Clinical Trials in Oncology: A Statistical Perspective ISBN: 0367729571 ISBN-13(EAN): 9780367729578 Издательство: Taylor&Francis Рейтинг: Цена: 8114.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is a textbook on the design and analysis of cancer clinical trials. It opens with a discussion of the choice of endpoints before moving onto discuss various types of trials across all phases of study, including basket trials, non-inferiority trials and multi-arm trials.
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