Описание: This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases.
Автор: Daniel L. Miller; M. Sharon Stack Название: Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer ISBN: 3319210998 ISBN-13(EAN): 9783319210995 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Moreover, individuals with HPV-positive OPSCC are generally younger and are frequently non-smokers, suggesting that HPV-associated OPSCC represents a distinct biologic entity.This volume summarizes the spectrum of current HPV-associated OPSCC research from the fundamental basic science to translational surgery and treatment approaches.
Автор: Daniel L. Miller; M. Sharon Stack Название: Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer ISBN: 3319354787 ISBN-13(EAN): 9783319354781 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Moreover, individuals with HPV-positive OPSCC are generally younger and are frequently non-smokers, suggesting that HPV-associated OPSCC represents a distinct biologic entity.This volume summarizes the spectrum of current HPV-associated OPSCC research from the fundamental basic science to translational surgery and treatment approaches.
Автор: Hatfield Dolph L., Schweizer Ulrich, Tsuji Petra A. Название: Selenium: Its Molecular Biology and Role in Human Health ISBN: 3319823132 ISBN-13(EAN): 9783319823133 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the current edition, Selenium: Its Molecular Biology and Role in Human Health expands extensively on the previous editions providing readers with the most significant advances in the rapidly developing selenium field. Evidence from epidemiology and veterinary science supports the essential role of selenium in (human) health, but its split personality in both preventing and supporting cancer and also in promoting insulin resistance has become more clearly defined. The pivotal role of glutathione peroxidase 4 in a new process of programmed cell death, ferroptosis, brings new impetus to the field. Recently defined mutations in selenoprotein and biosynthesis factor genes have been identified in patients, and the resulting disorders further emphasize the significance of selenoproteins in human health. The mechanism of selenoprotein biosynthesis, the functions of selenoproteins, and the roles of dietary selenium have been further elucidated, and new regulatory mechanisms involving selenoproteins discovered. The book, therefore, covers the breadth of current selenium research. With up-to-date chapters written by leaders in their fields, it serves as an invaluable resource for novices as well as specialists.
Автор: Gerhard Gross Название: Stem Cell-dependent Therapies ISBN: 3110298260 ISBN-13(EAN): 9783110298260 Издательство: Walter de Gruyter Цена: 31603.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activities by interfering with inflammatory cytokine production and with T- and B-cell proliferation. These immunomodulating properties make MSCs promising candidates for the treatment of chronic inflammatory and autoimmune disorders. There are, however, certain caveats involved including inappropriate migration of cells in the body, immune rejection, tumor formation, or graft versus host disease (GvHD). This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis, various rheumatic and neurological disorders and, lastly, tumors and solid organ transplantations. This book also questions the immunoprivileged status of MSCs, discusses the therapeutic role of MSCs in experimental animal disease models and their translation to the corresponding human disorders, envisions a role for MSCs in tumor interventions and, lastly, describes a systems biology approach for stem cells and inflammation.
Описание: The recent explosion of information in innate immune pathways for recognition, effect or responses, and genetic regulation has given impetus to investigations into analogous pathways in the human immune response, which in turn has produced attendant insights into both normal physiology and immunopathology.
Автор: Jean-Pierre Cartron; Philippe Rouger Название: Molecular Basis of Human Blood Group Antigens ISBN: 030644853X ISBN-13(EAN): 9780306448539 Издательство: Springer Рейтинг: Цена: 43184.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The science of blood groups was born at the beginning of this century, when the field of immunology married that of genetics. The six consecutive editions of the unequaled Blood Groups in Man have long been considered as the bible of blood groupers.
Описание: This volume summarizes the state-of-the-art in the fast growing research area of modeling the influence of information-driven human behavior on the spread and control of infectious diseases. In particular, it features the two main and inter-related “core” topics: behavioral changes in response to global threats, for example, pandemic influenza, and the pseudo-rational opposition to vaccines. In order to make realistic predictions, modelers need to go beyond classical mathematical epidemiology to take these dynamic effects into account. With contributions from experts in this field, the book fills a void in the literature. It goes beyond classical texts, yet preserves the rationale of many of them by sticking to the underlying biology without compromising on scientific rigor. Epidemiologists, theoretical biologists, biophysicists, applied mathematicians, and PhD students will benefit from this book. However, it is also written for Public Health professionals interested in understanding models, and to advanced undergraduate students, since it only requires a working knowledge of mathematical epidemiology.
Автор: Yechiel Becker; E.-S. Huang; Gholamreza Darai Название: Molecular Aspects of Human Cytomegalovirus Diseases ISBN: 3642848524 ISBN-13(EAN): 9783642848520 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book the current knowledge on human cytomegalovirus(HCMV) as a human pathogen is lucidly summarized, bringingthe reader fully up to date with current knowledgeconcerning HCMV and all the known clincial and medicalaspects of diseases caused by, and associated with, HCMV.
Описание: The second volume continues to fill the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.
Название: Molecular immunology of neurological diseases ISBN: 0128219742 ISBN-13(EAN): 9780128219744 Издательство: Elsevier Science Рейтинг: Цена: 10434.00 р. Наличие на складе: Нет в наличии.
Описание: Chemical industries, dairy units, oil and gas refineries, petro-chemical complexes and fertilizer manufacturing units are few of those areas which are incomplete without anti-corrosive treatment for concrete surface. Environmental effects, spillage and dust- emission are few of those processes which can corrode concrete. Protection of concrete surface of constructed elements from corrosive attack "arising through very harsh corrosive conditions" from all those (and many more) sources of corrosion becomes a moral duty of a Civil Engineer. This book is an effort in this direction to share the applied knowledge with the budding Engineers so that they are aware of such protective measures to be taken for the situations they are put into which I am sure, you must have found it to be of significant importance. One save of production stoppage with use of knowledge contained in this book would serve the very purpose of bringing it out.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
