This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Patil Popat M Название: Discoveries In Pharmacological Sciences ISBN: 9814355070 ISBN-13(EAN): 9789814355070 Издательство: World Scientific Publishing Рейтинг: Цена: 27720.00 р. 39600.00-30% Наличие на складе: Есть (1 шт.) Описание: Throughout history, the perpetuation of species, the need for survival, and human curiosity, intelligence and skills provided the basis for the development of drug science. This title contains the history of herbal medicine as it emerged about 5,000 years ago.
Автор: Parimelazhagan Thangaraj Название: Pharmacological Assays of Plant-Based Natural Products ISBN: 3319800205 ISBN-13(EAN): 9783319800202 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant’s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.
Автор: Thangaraj Parimelazhagan Название: Pharmacological Assays of Plant-Based Natural Products ISBN: 3319268104 ISBN-13(EAN): 9783319268101 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc.
Автор: Mar?a Alejandra Alvarez Название: Pharmacological Properties of Native Plants from Argentina ISBN: 303020197X ISBN-13(EAN): 9783030201975 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aim of this book is to offer information about the Pharmacological Properties of Native Plants from Argentina to students, researchers and graduates interested in the fields of Ethnobotany, Pharmacognosy, Phytochemistry, Pharmacy, and Medicine. The book includes summary information about the native plants from Argentina with medical activity comprising their botanical characteristics, distribution, characteristics of the regions where they grow, ethnobotanical information, chemical data, biological activity, establishment of in vitro cultures, toxicity, and legal status.
Автор: Alvarez Marнa Alejandra Название: Pharmacological Properties of Native Plants from Argentina ISBN: 3030202003 ISBN-13(EAN): 9783030202002 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aim of this book is to offer information about the Pharmacological Properties of Native Plants from Argentina to students, researchers and graduates interested in the fields of Ethnobotany, Pharmacognosy, Phytochemistry, Pharmacy, and Medicine. The book includes summary information about the native plants from Argentina with medical activity comprising their botanical characteristics, distribution, characteristics of the regions where they grow, ethnobotanical information, chemical data, biological activity, establishment of in vitro cultures, toxicity, and legal status.
Описание: This set of six volumes provides a systematic and standardized description of 23,033 chemical components isolated from 6,926 medicinal plants, collected from 5,535 books/articles published in Chinese and international journals. A chemical structure with stereo-chemistry bonds is provided for each chemical component, in addition to conventional information, such as Chinese and English names, physical and chemical properties. It includes a name list of medicinal plants from which the chemical component was isolated. Furthermore, abundant pharmacological data for nearly 8,000 chemical components are presented, including experimental method, experimental animal, cell type, quantitative data, as well as control compound data. The seven indexes allow for complete cross-indexing. Regardless whether one searches for the molecular formula of a compound, the pharmacological activity of a compound, or the English name of a plant, the information in the book can be retrieved in multiple ways.
Описание: This 6 volume set offers a systematic, standardized description of 23,033 chemical components isolated from 6,926 medicinal plants, collected from 5,535 books and articles published in Chinese and international journals, organized for easy retrieval and use.
Описание: A vast majority of the world's population lacks access to essential medicines and the provision of safe healthcare services. Medicinal plants and herbal medicines can be applied for pharmacognosy, or the discovery of new drugs, or as an aid for plant physiology studies. In recent years, there has been increased interest in the search for new chemical entities and the expression of resistance of many drugs available in the market has led to a shift in paradigm towards medicinal research. Herbal treatments, the most popular form of folk medicine, may become an important way of increasing access to healthcare services.
Handbook of Research on Pharmacological Uses of Medicinal Plants and Natural Products provides emerging research exploring the theoretical and practical aspects of drug discovery from natural sources that allow for the effective treatment of human health problems without any side effects, toxicity, or drug resistance. Featuring coverage on a broad range of topics such as ethnobotany, therapeutic applications, and bioactive compounds, this book is ideally designed for pharmacologists, scientists, ethnobotanists, botanists, health researchers, professors, industry professionals, and health students in fields that include pharmaceutical drug development and discovery.
Автор: Du, Guanhua Название: Pharmacological Advances In Natural Product Drug Discovery,87 ISBN: 0128201851 ISBN-13(EAN): 9780128201855 Издательство: Elsevier Science Рейтинг: Цена: 32002.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Pharmacological Advances in Natural Product Drug Discovery, Volume 87 in the Advances in Pharmacology series, presents the latest pharmacological research progresses of 8 medicinal compounds from natural products, including salvianolic acid, tanshinone, paeonol, chlorogenic acid, astragaloside, icariin, ganoderan, and febrifugine. Specific chapters to this new release include Potential Role of Paeonol on Atherosclerosis Related Cells, A Review on Salvianolic Acid, Pharmacological Advances of Tanshinones, the Natural Product of Salvia Miltiorrhiza, Pharmacological Action and Potential Targets Analysis of Major Pharmacological Effects of Chlorogenic Acid, Modern TCM: Identifying and Defining the Medicinal Mix, Pharmacological Advances in Astragaloside IV Derived from Astragalus Membranaceus, and much more.
