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Mendelian randomization, Burgess, Stephen (mrc Biostatistics Unit, Cambridge, Uk) Thompson, Simon G. (department Of Public Health And Primary Care, University Of Cambridge, Uk


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Автор: Burgess, Stephen (mrc Biostatistics Unit, Cambridge, Uk) Thompson, Simon G. (department Of Public Health And Primary Care, University Of Cambridge, Uk
Название:  Mendelian randomization
ISBN: 9781032019512
Издательство: Taylor&Francis
Классификация:


ISBN-10: 1032019514
Обложка/Формат: Paperback
Страницы: 226
Вес: 0.37 кг.
Дата издания: 29.06.2021
Серия: Chapman & hall/crc interdisciplinary statistics
Язык: English
Издание: 2 ed
Иллюстрации: 10 tables, black and white; 38 line drawings, black and white; 38 illustrations, black and white
Размер: 23.39 x 15.60 x 1.30 cm
Читательская аудитория: Tertiary education (us: college)
Подзаголовок: Methods for causal inference using genetic variants
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Поставляется из: Европейский союз
Описание: Mendelian randomization (MR) uses genetic instrumental variables to make inferences about causal effects based on observational data. It, therefore, can be a reliable way of assessing the causal nature of risk factors, such as biomarkers, for a wide range of disease outcomes.


Randomization, Bootstrap and Monte Carlo Methods in Biology

Автор: Manly, Bryan F.J. , Navarro Alberto, Jorge A.
Название: Randomization, Bootstrap and Monte Carlo Methods in Biology
ISBN: 0367349949 ISBN-13(EAN): 9780367349943
Издательство: Taylor&Francis
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Цена: 19906.00 р.
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Описание: The fourth edition of the book illustrates a large number of statistical methods with an emphasis on biological applications. It provides comprehensive coverage of computer-intensive applications, with datasets available online.

Randomization, Masking, and Allocation Concealment

Автор: Berger Vance
Название: Randomization, Masking, and Allocation Concealment
ISBN: 036773561X ISBN-13(EAN): 9780367735616
Издательство: Taylor&Francis
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Цена: 7501.00 р.
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Описание:

Randomization, Masking, and Allocation Concealment is indispensable for any trial researcher who wants to use state of the art randomization methods, and also wants to be able to describe these methods correctly.

Far too often the subtle nuances that distinguish proper randomization from flawed randomization are completely ignored in trial reports that state only that randomization was used, with no additional information. Experience has shown that in many cases, the type of randomization that was used was flawed. It is only a matter of time before medical journals and regulatory agencies come to realize that we can no longer rely on (or publish) flawed trials, and that flawed randomization in and of itself disqualifies a trial from being robust or high quality, even if that trial is of high quality otherwise.

This book will help to clarify the role randomization plays in ensuring internal validity, and in drawing valid inferences from the data. The various chapters cover a variety of randomization methods, and are not limited to the most common (and most flawed) ones. Readers will come away with a profound understanding of what constitutes a valid randomization procedure, so that they can distinguish the valid from the flawed among not only existing methods but also methods yet to be developed.

Design and Analysis of Cluster Randomization Trials in Health Research

Автор: Allan Donner, Neil Klar
Название: Design and Analysis of Cluster Randomization Trials in Health Research
ISBN: 0470711000 ISBN-13(EAN): 9780470711002
Издательство: Wiley
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Цена: 10130.00 р.
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Описание: A cluster randomization trial is one in which intact social units, or clusters of individuals, are randomized to different intervention groups.


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