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Experimental Models of Parkinson`s Disease, Imai Yuzuru


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Автор: Imai Yuzuru
Название:  Experimental Models of Parkinson`s Disease
ISBN: 9781071614945
Издательство: Springer
Классификация:


ISBN-10: 1071614940
Обложка/Формат: Hardcover
Страницы: 217
Вес: 0.59 кг.
Дата издания: 28.06.2021
Язык: English
Размер: 25.91 x 19.81 x 1.78 cm
Ссылка на Издательство: Link
Поставляется из: Германии
Описание:

Part I: Biochemical Experiments and Cellular Models of Parkinsons Disease

1. α-Synuclein Seeding Assay Using RT-QuIC

Ayami Okuzumi, Taku Hatano, Takeshi Fukuhara, Shinichi Ueno, Nobuyuki Nukina, Yuzuru Imai, and Nobutaka Hattori

2. Electron-Microscopic Analysis of α-Synuclein Fibrils

Airi Tarutani and Masato Hasegawa

3. α-Synuclein Seeding Assay Using Cultured Cells

Jun Ogata, Daisaku Takemoto, Shotaro Shimonaka, Yuzuru Imai, and Nobutaka Hattori

4. Analysis of α-Synuclein in Exosomes

Taiji Tsunemi, Yuta Ishiguro, Asako Yoroisaka, and Nobutaka Hattori

5. Measurement of GCase Activity in Cultured Cells

Yuri Shojima, Jun Ogata, Taiji Tsunemi, Yuzuru Imai, and Nobutaka Hattori

6. Detection of Substrate Phosphorylation of LRRK2 in Tissues and Cultured Cells

Kyohei Ito, Lejia Xu, Genta Ito, and Taisuke Tomita

7. Two Methods to Analyze LRRK2 Functions Under Lysosomal Stress: The Measurements of Cathepsin Release and Lysosomal Enlargement

Maria Sakurai and Tomoki Kuwahara

8. Differentiation of Midbrain Dopaminergic Neurons from Human iPS Cells

Kei-ichi Ishikawa, Risa Nonaka, and Wado Akamatsu

9. Monitoring PINK1-Parkin Signaling Using Dopaminergic Neurons from iPS Cells

Kahori Shiba-Fukushima and Yuzuru Imai

Part II: Mammalian Models of Parkinsons Disease

10. Generation of Mitochondrial Toxin Rodent Models of Parkinsons Disease Using 6-OHDA, MPTP, and Rotenone

Hiroharu Maegawa and Hitoshi Niwa

11. Midbrain Slice Culture as an Ex Vivo Analysis Platform for Parkinsons Disease

Yuji Kamikubo, Keiko Wakisaka, Yuzuru Imai, and Takashi Sakurai

12. α-Synuclein Propagation Mouse Models of Parkinsons Disease

Norihito Uemura, Jun Ueda, Shinya Okuda, Masanori Sawamura, and Ryosuke Takahashi

13. Common Marmoset Model of α-Synuclein Propagation

Masami Masuda-Suzukake, Aki Shimozawa, Masashi Hashimoto, and Masato Hasegawa

14. Application of a Tissue Clearing Method for the Analysis of Dopaminergic Axonal Projections

Kenta Yamauchi, Megumu Takahashi, and Hiroyuki Hioki

15. Deep Brain Stimulation Using Animal Models of Parkinsons Disease

Asuka Nakajima and Yasushi Shimo

Part III: Invertebrate Models of Parkinsons Disease

16. Assessment of Cytotoxicity of α-Synuclein in Budding Yeast Using a Spot Growth Assay and Fluorescent Microscopy

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Rubins Pathology  8 Ed. IE.

Автор: David S Strayer
Название: Rubins Pathology 8 Ed. IE.
ISBN: 1975141024 ISBN-13(EAN): 9781975141028
Издательство: Lippincott Williams & Wilkins
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Цена: 15135.00 р.
Наличие на складе: Есть (4 шт.)
Описание: Learn how to sail the world`s most popular junior sailing boat fast. Originally written by Ben Ainslie`s Optimist coach, this new edition has been completely updated by top coach Steve Irish. It shows how to achieve blistering boatspeed through technique and tuning, perfect boat handling and tactics as well as covering the mental and physical side.

Robbins & Cotran Pathologic Basis Of Disease 10 ed.

Автор: Vinay Kumar, Abul K. Abbas, Jon C. Aster
Название: Robbins & Cotran Pathologic Basis Of Disease 10 ed.
ISBN: 032353113X ISBN-13(EAN): 9780323531139
Издательство: Elsevier Science
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Цена: 16673.00 р.
Наличие на складе: Есть (1 шт.)
Описание: Readable and highly illustrated, Robbins and Cotran Pathologic Basis of Disease, 10th Edition presents an in-depth, state-of-the-art overview of human diseases and their cellular and molecular basis. This best-selling text delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. More than 1,000 high-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more. This superb learning package also includes an enhanced eBook with a full complement of ancillary content on Student Consult.

  • Provides uniquely authoritative and readable coverage, ideal for USMLE or specialty board preparation, as well as for coursework.
  • Covers the hot topics you need to know about, including novel therapies for hepatitis C, classification of lymphomas, unfolded protein response, non-apoptotic pathways of cell death, coronavirus infections, liquid biopsy for cancer detection, regulation of iron absorption, clonal hematopoiesis and atherosclerosis, thrombotic microangiopathies, heparin-induced thrombocytopenias, inflammatory myopathies, genetic tools for treatment of cystic fibrosis, and many more.
  • Uses an outstanding full-color, user-friendly design to simplify your study and quickly direct you to the information you need to know, with learning features such as boldface overviews at the beginning of each section, key concepts boxes, suggested readings, schematic diagrams that illustrate complex concepts, and new gross and microscopic figures for clarity of morphology.
  • Brings you up to date with the latest information in molecular and genetic testing, mechanisms of disease, personalized medicine and its impact on treatment of human diseases, the role of microbiome and metabolome in non-communicable diseases, and much more.
  • Provides access to a wealth of interactive ancillaries online: pathology case studies, videos, self-assessment questions, Targeted Therapy boxes that discuss drug therapy for specific diseases, interactive cases, and more.
  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices
Robbins and Cotran Pathologic Basis of Disease.-9 ed.

Автор: Abbas, Abul K. Fausto, Nelson Kumar, Vinay
Название: Robbins and Cotran Pathologic Basis of Disease.-9 ed.
ISBN: 0808924508 ISBN-13(EAN): 9780808924500
Издательство: Elsevier Science
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Цена: 9136.00 р.
Наличие на складе: Нет в наличии.

Описание: Ashton B. Carter said when announcing that the Pentagon would open all combat jobs to women, "I made a commitment to building America`s force of the future. In the twenty-first century, that requires drawing strength from the broadest possible pool of talent." William Taylor chronicles and analyses the long and ever-changing history of that often contentious and controversial effort.

Braunwald`s Heart Disease: A Textbook of Cardiovascular Medicine

Автор: , Zipes , Libby , Bonow , Mann , Tomaselli
Название: Braunwald`s Heart Disease: A Textbook of Cardiovascular Medicine
ISBN: 0323555926 ISBN-13(EAN): 9780323555920
Издательство: Elsevier Science
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Цена: 22695.00 р.
Наличие на складе: Нет в наличии.

Описание: Trusted by generations of cardiologists for the latest, most reliable guidance in the field, Braunwald’s Heart Disease, 11th Edition, remains your #1 source of information on rapidly changing clinical science, clinical and translational research, and evidence-based medicine. This award-winning text has been completely updated, providing a superior multimedia reference for every aspect of this fast-changing field, including new material about almost every topic in cardiology.

Mims` Pathogenesis of Infectious Disease, 6 ed.

Автор: Anthony A. Nash, Robert G. Dalziel, J.Ross Fitzger
Название: Mims` Pathogenesis of Infectious Disease, 6 ed.
ISBN: 0123971888 ISBN-13(EAN): 9780123971883
Издательство: Elsevier Science
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Цена: 5422.00 р. 7746.00 -30%
Наличие на складе: Есть (1 шт.)
Описание: Mims' Pathogenesis of Infectious Disease is the landmark book in the field of infectious disease. The new, revised edition of this work provides a comprehensive, up-to-date description of the mechanisms of microbial infection and the pathogenesis of infectious disease. Presented in a clear, accessible style, it deals in an integrated manner with the spectrum of microorganisms, describing the factors common to all infectious diseases. Molecular biology, pathology, and immunology are brought together to explain the mechanisms for spread, immune response, and recovery.

  • Describes the origin and molecular biology of pandemic influenza, HIV1, and HIV2 as well as the recent work on papillomaviruses, herpesviruses, BSE, and variant CJD
  • Contains the latest data on tuberculosis, microbial evasion of immune defenses, and the spread of antibiotic resistance genes among bacteria
  • Provides an update on vaccines, prions, immune evasion, and microbial ligands and receptors
  • Gives an up-to-date picture of the global burden of infectious diseases
Pocket Companion to Robbins & Cotran Pathologic Basis of Disease, International edition: Elsevier Science, 2015.- ISBN:  9780323296403/Ричард Митчелл: Карманный справочник по патологии Робинса и Котрана

Автор: Mitchell, Richard N., M.D., Ph.D. Kumar, Vinay Fausto, Nelson Abbas, Abul K. Aster, Jon C.
Название: Pocket Companion to Robbins & Cotran Pathologic Basis of Disease, International edition: Elsevier Science, 2015.- ISBN: 9780323296403/Ричард Митчелл: Карманный справочник по патологии Робинса и Котрана
ISBN: 0323296408 ISBN-13(EAN): 9780323296403
Издательство: Elsevier Science
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Цена: 4125.00 р.
Наличие на складе: Нет в наличии.

Описание: Complemented by: Robbins and Cotran pathologic basis of disease / [edited by] Vinay Kumar, Abul K. Abbas, Jon C. Aster. Ninth edition. [2015].

Rating Scales in Parkinson`s Disease  Clinical Practice and Research

Автор: Cristina Sampaio, Christopher G. Goetz...
Название: Rating Scales in Parkinson`s Disease Clinical Practice and Research
ISBN: 0199783101 ISBN-13(EAN): 9780199783106
Издательство: Oxford Academ
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Цена: 12197.00 р. 17424.00 -30%
Наличие на складе: Есть (1 шт.)
Описание: Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one convenient source. Until now. Rating Scales in Parkinson's Disease: Clinical Practice and Research is written for researchers from the medical and social sciences, and for health professionals wishing to evaluate the progress of their patients suffering from Parkinson's Disease. The book is both exhaustive in the description of the scales and informative on the advantages and limitations of each scale. As such, the text clearly guides readers on how to choose and use the instruments available. Extensive cross-referenced tables and charts closely integrate the parts of the book to facilitate readers in moving from one symptom domain to another. Features Based on a consistent and uniform methodology A clear consolidation of material otherwise only available in journals The first comprehensive book of its kind

Cambridge Handbook of Experimental Political Science

Автор: Druckman
Название: Cambridge Handbook of Experimental Political Science
ISBN: 0521192129 ISBN-13(EAN): 9780521192125
Издательство: Cambridge Academ
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Цена: 17266.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Laboratory experiments, survey experiments and field experiments occupy a central and growing place in the discipline of political science. This volume provides the first comprehensive overview of how political scientists have used experiments to make important discoveries and transform their field of study.

Encyclopedia of Parkinson`s Disease: Volume V (Models and Modules)

Автор: White Kate
Название: Encyclopedia of Parkinson`s Disease: Volume V (Models and Modules)
ISBN: 1632411938 ISBN-13(EAN): 9781632411938
Издательство: Неизвестно
Цена: 18507.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book on Parkinson's disease (PD) elaborates the state-of-the-art research in the field. PD is caused mainly due to the death of dopaminergic neurons in the substantia nigra. Recent PD medications treat symptoms; though none decrease the rate of dopam

Experimental Techniques in Plant Disease Epidemiology

Автор: J?rgen Kranz; Joseph Rotem
Название: Experimental Techniques in Plant Disease Epidemiology
ISBN: 3642955363 ISBN-13(EAN): 9783642955365
Издательство: Springer
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Цена: 15672.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Most books on epidemiology have treated the subject from a statistical, mathematical or computer applicational point of view. However, experiments must be performed first to provide the data for models which in turn can then be proven by further experimentation.

Malignant Lymphomas and Hodgkin`s Disease: Experimental and Therapeutic Advances

Автор: Franco Cavalli; Gianni Bonadonna; Marcel Rozencwei
Название: Malignant Lymphomas and Hodgkin`s Disease: Experimental and Therapeutic Advances
ISBN: 0898387272 ISBN-13(EAN): 9780898387278
Издательство: Springer
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Цена: 54365.00 р.
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Описание: Proceedings of the Second International Conference on Malignant Lymphomas, Lugano, Switzerland, June 13-16, 1984

Malignant Lymphomas and Hodgkin`s Disease: Experimental and Therapeutic Advances

Автор: Franco Cavalli; Gianni Bonadonna; Marcel Rozencwei
Название: Malignant Lymphomas and Hodgkin`s Disease: Experimental and Therapeutic Advances
ISBN: 1461296323 ISBN-13(EAN): 9781461296324
Издательство: Springer
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Цена: 54365.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Proceedings of the Second International Conference on Malignant Lymphomas, Lugano, Switzerland, June 13-16, 1984


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