Описание: Proceedings of a NATO ARW held in Luso, Portugal, June 1-5, 1992
Автор: Moskalev Alexey Название: Biomarkers of Human Aging ISBN: 3030249727 ISBN-13(EAN): 9783030249724 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging. In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function). The book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging. Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.
Описание: This book is the first of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality.
1. Research in the Middle East into the Health Benefits of Curcumin
2. Turmeric and Curcumin: From Traditional to Modern Medicine
3. Targeting Nuclear Factor-kappa B signaling pathway by curcumin: implications for the treatment of multiple sclerosis
4. Carbon-based Nanomaterials and Curcumin: a Review of Biosensing Applications
5. Effects of Curcumin and its Analogues on Bacterial and Parasitic Infectious Diseases
6. Protective Effects of Curcumin on Endothelium: an Updated Review
7. The Effect of Curcumin Supplementation on Anthropometric Indices in Overweight and Obese Individuals: A Systematic Review of Randomized Controlled Trials
8. Effect of Curcumin on Glycemic Control in Patients with Type 2 Diabetes: A Systematic Review of Randomized Clinical Trials
9. Anti-diabetic Properties of Curcumin: Insights on New Mechanisms
10. The effect of Curcumin in improving Lipid Profile in Patients with Cardiovascular Risk Factors: a Systematic Review of Clinical Trials
11. The effects of curcumin in the treatment of gingivitis: A systematic review of clinical trials
12. Does Curcumin have an Anti-caries Effect? A Systematic Review of In vitro Studies
13. The clinical use of curcumin for the treatment of recurrent aphthous stomatitis: A systematic review of clinical trials
14. Antibacterial Activity of Curcumin against Periodontal Pathogens: A Systematic Review
15. The Clinical use of Curcumin for the Treatment of Rheumatoid Arthritis: A Systematic Review of Clinical Trials
16. A Systematic Review of the Clinical use of Curcumin for Treatment of Osteoarthritis
17. Effects of Curcumin on Depression and Anxiety: A Narrative Review of the Recent Clinical Data
18. A Systematic Review of the Clinical use of Curcumin for Management of Gastrointestinal Diseases
19. The use of Curcumin for the Treatment of Renal Disorders: a Systematic Review of Randomized Controlled Trials
20. Curcumin for the Treatment of Prostate Diseases: a Systematic Review of Controlled Clinical Trials
21. Curcumin: a Review of its Effects on Epilepsy
Index
Автор: El Bairi Khalid Название: Ovarian Cancer Biomarkers: Mapping to Improve Outcomes ISBN: 9811618720 ISBN-13(EAN): 9789811618727 Издательство: Springer Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer.
Автор: Kyung-Hyun Cho Название: High-Density Lipoproteins as Biomarkers and Therapeutic Tools ISBN: 9811373825 ISBN-13(EAN): 9789811373824 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is the second of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. In this volume, the focus is on the improvement of HDL, enhancement of its functionality, and the use of HDL for therapeutic purposes. In the first section, up-to-date information is provided on such topics as the tumor regression-promoting and antidiabetic activities of reconstituted HDL containing V156K apolipoprotein A-I, the enhancement of HDL effects by high doses of vitamin C, the benefits derived from incorporation of growth hormones 1 and 2 into rHDL, and the biological functions of omega-3 linolenic acid in rHDL. The enhancement of HDL functionality by policosanol and the resultant benefits are thoroughly examined in a separate section. Readers will also find the latest information on clinical applications of HDL. Here, specific topics include the enhancement of adenoviral gene delivery and the delivery of rapamycin. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.
Автор: Alexey Moskalev Название: Biomarkers of Human Aging ISBN: 3030249697 ISBN-13(EAN): 9783030249694 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging.In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function).The book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging.Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.
Автор: Frank M. Butterworth; Amara Gunatilaka; Mar?a Euge Название: Biomonitors and Biomarkers as Indicators of Environmental Change 2 ISBN: 1461354889 ISBN-13(EAN): 9781461354888 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Monitoring the environment is absolutely essential if we are to identify hazards to human health, to assess environmental cleanup efforts, and to prevent further degradation of the ecosystem.
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