Описание: This second edition provides techniques used to study of the underlying transcriptional programs of stem cells that promote self-renewal and differentiation. Chapters detail next-generation sequencing technologies, data analysis, protocols on analysis and visualization of single-cell RNA-Seq data, analysis of 3D chromatin architecture, interpretation of large-scale interaction networks, transcriptional networks in embryonic and adult stem cells, derivation of stem cells, and transcriptional programs that promote reprogramming, transdifferentiation, and cancer formation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Stem Cell Transcriptional Network: Methods and Protocols, Second Edition aims to provide a key resource for biologists seeking to interrogate these vital networks.
Описание: This volume takes two approaches to this topic - (1) illustrating the general principles outlined above through a series of different stem cell examples - embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.
Описание: This volume describes a variety of protocols that will allow the readers to study different aspects of transcriptional and posttranscriptional gene expression regulation in eukaryotic cells.
Автор: Dudek Название: Transcriptional Regulation by Neuronal Activity ISBN: 144194463X ISBN-13(EAN): 9781441944634 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Regulation of gene transcription by neuronal activity is evident in a large number of neuronal processes ranging from neural development and refinement of neuronal connections to learning and response to injury.
Автор: Dassi Erik Название: Post-Transcriptional Gene Regulation ISBN: 1071618504 ISBN-13(EAN): 9781071618509 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume presents the most recent advances in techniques for studying the post-transcriptional regulation of gene expression (PTR).
Автор: Jeffrey Wilusz Название: Post-Transcriptional Gene Regulation ISBN: 1617377767 ISBN-13(EAN): 9781617377761 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With chapters split into sections covering bioinformatics, fundamental aspects of the study of RNA biology, and techniques for specific aspects of RNA biology, the expert authors have filled the book with invaluable tricks of the trade, perfected in their laboratories.
Автор: K.M.J. Menon, PhD; Aaron Goldstrohm, PhD Название: Post-transcriptional Mechanisms in Endocrine Regulation ISBN: 3319251228 ISBN-13(EAN): 9783319251226 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones.
Автор: Menon Phd K. M. J., Goldstrohm Phd Aaron Название: Post-Transcriptional Mechanisms in Endocrine Regulation ISBN: 3319797387 ISBN-13(EAN): 9783319797380 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines how post-transcriptional mechanisms control endocrine function. This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones. The impacts of these mechanisms on disease and health are covered, providing a novel update to the scientific literature. Post-transcriptional regulatory mechanisms play an essential role in controlling dynamic gene expression. The outcome of this regulation includes control of the amount, timing, and location of protein expression. Regulation is mediated by cis-acting RNA sequences and structures and transacting RNA binding proteins and non-coding RNAs, including microRNAs. Recent advances in characterization of these regulatory factors have revealed enormous regulatory potential.
Автор: Ales Vancura Название: Transcriptional Regulation ISBN: 1493958542 ISBN-13(EAN): 9781493958542 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book exemplifies recent advances in transcriptional regulation with a set of key cutting-edge protocols from around the world. It explores topics ranging from transcription factors to pre-initiation complex (PIC) assembly and RNA synthesis and regulation.
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