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In Silico Modeling of Drugs Against Coronaviruses: Computational Tools and Protocols, Roy Kunal


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Автор: Roy Kunal
Название:  In Silico Modeling of Drugs Against Coronaviruses: Computational Tools and Protocols
ISBN: 9781071613658
Издательство: Springer
Классификация:




ISBN-10: 1071613650
Обложка/Формат: Hardcover
Страницы: 788
Вес: 1.59 кг.
Дата издания: 12.09.2021
Язык: English
Размер: 25.91 x 20.32 x 4.32 cm
Ссылка на Издательство: Link
Поставляется из: Германии
Описание: This detailed book aims to provide an overview of novel bioinformatics resources for exploring diverse aspects of RNA biology. This edition focuses on methods dealing with non-coding RNA (miRNAs, circRNAs or lncRNAs), RNA modifications (m6A or RNA editing), single cell RNA-seq and statistical models to handle count data from RNA-seq experiments.


Coronaviruses

Автор: Helena J. Maier; Erica Bickerton
Название: Coronaviruses
ISBN: 1071608991 ISBN-13(EAN): 9781071608999
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This detailed new edition provides a comprehensive collection of protocols applicable to all members of the Coronavirinae sub-family currently and that are also transferrable to other fields of virology.

Coronaviruses and Other Novel Antiviral Targets, 57

Название: Coronaviruses and Other Novel Antiviral Targets, 57
ISBN: 0323915116 ISBN-13(EAN): 9780323915113
Издательство: Elsevier Science
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Цена: 23075.00 р.
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Описание:

Annual Reports in Medicinal Chemistry, Volume 57 in this long-running series, highlights new advances in the field with this new volume presenting interesting chapters on the Mechanism of action of the broadly acting antiviral drug remdesivir, Improving properties of the nucleobase analogue T-706 as a potential anti-SARS-CoV-2 and anti-influenza compound, Antivirals for RNA virus infections Anno 2020-2021, Broad spectrum antiviral fleximer nucleosides, SARS-CoV-2 main protease inhibitors, The search for antivirals to treat alphavirus infections, Inhibitors of Ebola Virus targeting Innate immune evasion, Uracil derivatives as non-nucleoside inhibitors of viral infections, and more.

Coronaviruses

Автор: Hubert Laude; Jean-Francois Vautherot
Название: Coronaviruses
ISBN: 1461363055 ISBN-13(EAN): 9781461363057
Издательство: Springer
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Цена: 6986.00 р.
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Описание: The present volume collects 75 papers which were presented during the yth symposium, thus providing a comprehensive view of the state of the art ofCoronavirology. New sequence data about as yet poorly studied coronaviruses - canine coronavirus CCY and porcine epidemic diarrhoea virus PEDY - are presented.

Diagnostic Strategies for Covid-19 and Other Coronaviruses

Автор: Chandra Pranjal, Roy Sharmili
Название: Diagnostic Strategies for Covid-19 and Other Coronaviruses
ISBN: 9811560056 ISBN-13(EAN): 9789811560057
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book provides fundamental information on various techniques for the detection of SARS-CoV-2 including reverse transcriptase (RT) PCR, loop-mediated isothermal amplification, immunodiagnostic tests, and CRISPR-Cas.

SARS- and Other Coronaviruses

Автор: Cavanagh
Название: SARS- and Other Coronaviruses
ISBN: 1617378151 ISBN-13(EAN): 9781617378157
Издательство: Springer
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Цена: 19564.00 р.
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Описание: In 2003, the word "coronavirus" spread across the globe, somewhat further than the virus that sparked the panic. In this book, expert researchers examine these devastating viruses through 23 state-of-the-art, widely applicable protocols with minute detail.

Biochemistry and Biology of Coronaviruses

Автор: V. Ter Meulen
Название: Biochemistry and Biology of Coronaviruses
ISBN: 1475704585 ISBN-13(EAN): 9781475704587
Издательство: Springer
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Цена: 13974.00 р.
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Описание: The uniformity and diversity in this virus group was evaluated from a molecular point of view and the replication of coronaviruses appears to involve aspects which may be unique for this virus group.

Quantitative in Silico Chromatography: Computational Modelling of Molecular Interactions

Название: Quantitative in Silico Chromatography: Computational Modelling of Molecular Interactions
ISBN: 1849739919 ISBN-13(EAN): 9781849739917
Издательство: Royal Society of Chemistry
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Цена: 30624.00 р.
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Описание: Written by the author of "HPLC: A Practical Guide" (RSC, 1999),this book presents the possibilities for characterising biological applications by combining analytical and computational chemistries.

In Silico Drug Design

Автор: Roy, Kunal
Название: In Silico Drug Design
ISBN: 0128161256 ISBN-13(EAN): 9780128161258
Издательство: Elsevier Science
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Цена: 23075.00 р.
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Описание:

In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. Other topics include in silico drug design methods, computational workflows for drug repurposing, and network-based in silico screening for drug efficacy. With contributions from experts in the field and the inclusion of practical case studies, this book gives scientists, researchers and R&D professionals in the pharmaceutical industry valuable insights into drug design.

  • Discusses the theoretical background and methodologies of useful techniques of cheminformatics and bioinformatics that can be applied for drug repurposing
  • Offers case studies relating to the in silico modeling of FDA-approved drugs for the discovery of antifungal, anticancer, antiplatelet agents, and for drug therapies against diseases
  • Covers tools and databases that can be utilized to facilitate in silico methods for drug repurposing
In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications

Автор: Claudio N. Cavasotto
Название: In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications
ISBN: 1138747580 ISBN-13(EAN): 9781138747586
Издательство: Taylor&Francis
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Цена: 14086.00 р.
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Описание: This text provides an overview of the current methodological strategies in computer-aided drug discovery and design.

In Silico Models for Drug Discovery

Автор: Sandhya Kortagere
Название: In Silico Models for Drug Discovery
ISBN: 1627033416 ISBN-13(EAN): 9781627033411
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This Methods in Molecular Biology (TM) book surveys in silico models, offering techniques to derive novel antimicrobial targets and methods for computing binding energies of drugs to their target proteins, plus protocols, materials lists, known pitfalls and more.

Molecular Biology and Pathogenesis of Coronaviruses

Автор: P. J. Rottier
Название: Molecular Biology and Pathogenesis of Coronaviruses
ISBN: 1461593751 ISBN-13(EAN): 9781461593751
Издательство: Springer
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Цена: 6986.00 р.
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Coronaviruses

Автор: Helena Jane Maier; Erica Bickerton; Paul Britton
Название: Coronaviruses
ISBN: 1493924370 ISBN-13(EAN): 9781493924370
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This volume aims to describe a variety of techniques that reflects the wide range of research currently performed in the field of coronavirology, and begins with an overview of current understandings of coronavirus replication and pathogenesis to introduce specialists and non-specialists to the field. The rest of the book is divided into several sections of chapters beginning with those that describe identification, diagnosis, and study of the evolution of coronaviruses. The next few chapters discuss the preparation of cells and organ cultures useful in propagating coronaviruses and titration techniques, as well as techniques for analyzing virus functions that require purification of the viruses. The next chapters describe two commonly used reverse genetics techniques for coronaviruses, and techniques detailing identification of cellular receptors, binding profiles of viral attachment proteins, and virus-cell fusion. The final chapters cover a broad spectrum of techniques to identify virus-host protein-protein interactions, confirm the functional role of these proteins in virus replication, study host cell responses through genome-wide or pathway-specific approaches, and visualize virus replication complexes. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and practical, Coronaviruses: Methods and Protocols appeals to a wide variety of scientists because it highlights techniques that are currently used in the coronovirology field, while also discussing practices applicable to other virology fields.


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