Описание: What every neuroscientist should know about the mathematical modeling of excitable cells. Combining empirical physiology and nonlinear dynamics, this text provides an introduction to the simulation and modeling of dynamic phenomena in cell biology and neuroscience. It introduces mathematical modeling techniques alongside cellular electrophysiology. Topics include membrane transport and diffusion, the biophysics of excitable membranes, the gating of voltage and ligand-gated ion channels, intracellular calcium signalling, and electrical bursting in neurons and other excitable cell types. It introduces mathematical modeling techniques such as ordinary differential equations, phase plane, and bifurcation analysis of single-compartment neuron models. With analytical and computational problem sets, this book is suitable for life sciences majors, in biology to neuroscience, with one year of calculus, as well as graduate students looking for a primer on membrane excitability and calcium signalling.
Описание: 1 Paradigms in Epidemiology1.1 Methodological Paradigms1.2 Recent Developments1.3 Infectious Diseases and Vaccination 1.4 Objectives and Tasks 1.4.1 Modeling Infectious Disease Dynamics 1.4.2 Modeling Vaccine Allocation Strategies 1.4.3 Modeling Vaccination Decision-Making 1.4.4 Modeling Subjective Perception 1.5 Summary 2 Computational Modeling in a Nutshell2.1 Modeling Infectious Disease Dynamics 2.1.1 Infectious Disease Models 2.1.2 Age-Specific Disease Transmissions2.2 Modeling Contact Relationships 2.2.1 Empirical Methods 2.2.2 Computational Methods2.3 Case Study 2.3.1 2009 Hong Kong H1N1 Influenza Epidemic 2.3.2 Age-Specific Contact Matrices 2.3.3 Validation2.4 Further Remarks 2.5 Summary3 Strategizing Vaccine Allocation3.1 Vaccination3.1.1 Herd Immunity 3.1.2 Vaccine Allocation Strategy3.2 Vaccination Priorities 3.3 Age-Specific Intervention Priorities 3.3.1 Modeling Prioritized Interventions 3.3.2 Effects of Vaccination 3.3.3 Effects of Contact Reduction3.3.4 Integrated Measures 3.4 Case Study 3.4.1 2009 Hong Kong HSI Vaccination Programme 3.4.2 Effects of Prioritized Interventions3.5 Further Remarks3.6 Summary4 Explaining Individuals' Vaccination Decisions4.1 Costs and Benefits for Decision-Making4.2 Game-Theoretic Modeling of Vaccination Decision-Making4.3 Case Study 4.3.1 2009 Hong Kong HSI Vaccination Programme4.3.2 Vaccination Coverage 4.4 Further Remarks4.5 Summary 5 Characterizing Socially Influenced Vaccination Decisions 5.1 Social Influences on Vaccination Decision-Making 5.2 Case Study 5.2.1 Vaccination Coverage 5.3 Further Remarks5.4 Summary 6 Understanding the Effect of Social Media 6.1 Modeling Subjective Perception 6.2 Subjective Perception in Vaccination Decision-Making 6.2.1 Dempster-Shafer Theory (DST)6.2.2 Spread of Social Awareness 6.3 Case Study 6.3.1 Vaccination Decision-Making in an Online SocialCommunity6.3.2 Interplay of Two Dynamics 6.4 Further Remarks 6.5 Summary7 Welcome to the Era of Systems Epidemiology 7.1 Systems Thinking in Epidemiology 7.2 Systems Modeling in Principle7.3 Systems Modeling in Practice7.4 Toward Systems Epidemiology 8 Further Readings References
Описание: The book is intended for readers who are interested in learning about the use of computer-based modelling of the COVID-19 disease. It provides a basic introduction to a five-ordinary differential equation (ODE) model by providing a complete statement of the model, including a detailed discussion of the ODEs, initial conditions and parameters, followed by a line-by-line explanation of a set of R routines (R is a quality, scientific programming system readily available from the Internet). The reader can access and execute these routines without having to first study numerical algorithms and computer coding (programming) and can perform numerical experimentation with the model on modest computers.
Описание: Further, it examines models related to pandemic planning, such as evaluation of financial contagion, debt risk analysis, and health system efficiency performance, and addresses specific models of pandemic parameters. The book demonstrates various tools using available data on the ongoing COVID-19 pandemic.
Автор: Xia Название: A Mathematical Primer of Molecular Phylogenetics ISBN: 1771887559 ISBN-13(EAN): 9781771887557 Издательство: Taylor&Francis Рейтинг: Цена: 17762.00 р. Наличие на складе: Поставка под заказ.
Описание: The volume provides sufficient mathematical background for young mathematicians and computational scientists, as well as mathematically inclined biology students, to make a smooth entry into the expanding field of molecular phylogenetics.
Автор: Mansi, Tommaso Passerini, Tiziano Название: Artificial intelligence for computational modeling of the heart ISBN: 012817594X ISBN-13(EAN): 9780128175941 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Artificial Intelligence for Computational Modeling of the Heart presents recent research developments towards streamlined and automatic estimation of the digital twin of a patient's heart by combining computational modeling of heart physiology and artificial intelligence. The book first introduces the major aspects of multi-scale modeling of the heart, along with the compromises needed to achieve subject-specific simulations. Reader will then learn how AI technologies can unlock robust estimations of cardiac anatomy, obtain meta-models for real-time biophysical computations, and estimate model parameters from routine clinical data. Concepts are all illustrated through concrete clinical applications.
Presents recent advances in computational modeling of heart function and artificial intelligence technologies for subject-specific applications
Discusses AI-based technologies for robust anatomical modeling from medical images, data-driven reduction of multi-scale cardiac models, and estimations of physiological parameters from clinical data
Illustrates the technology through concrete clinical applications and discusses potential impacts and next steps needed for clinical translation
Автор: Vivek V. Ranade, Sanjay M Mahajani, Ganesh Arunkum Название: Computational Modeling of Underground Coal Gasification ISBN: 1138091596 ISBN-13(EAN): 9781138091597 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Поставка под заказ.
Описание: The book deals with development of comprehensive computational models for simulating underground coal gasification (UCG). It starts with an introduction to the UCG process and discuss known process models with relative merits and limitations of the modeling approaches are highlighted and compared.
Автор: Cesarone, Francesco Название: Computational Finance : MATLAB® Oriented Modeling ISBN: 0367492938 ISBN-13(EAN): 9780367492939 Издательство: Taylor&Francis Рейтинг: Цена: 5817.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The theoretical aspects of the book are based on an essential introduction to the building blocks of the two topics under consideration: mathematical programming and stochastic processes. It also includes a primer on MATLAB, as a tool to help students, scholars and practitioners use the concepts in the book.
Автор: Deng Weihua Название: Modeling Anomalous Diffusion: From Statistics To Mathematics ISBN: 9811212996 ISBN-13(EAN): 9789811212994 Издательство: World Scientific Publishing Рейтинг: Цена: 14256.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book focuses on modeling the anomalous diffusion phenomena, being ubiquitous in the natural world. Both the microscopic models (stochastic processes) and macroscopic models (partial differential equations) have been built up. The relationships between the two kinds of models are clarified, and based on these models, some statistical observables are analyzed. From statistics to mathematics, the built models show their power with their associated applications.
This book is important for students to develop basic skills to be able to succeed in their future research. In addition to introducing the related models or methods, it also provides the corresponding applications and simulation results, which will attract more readers ranging from mathematicians to physicists or chemists, to name a few.
Автор: Goran Rakocevic; Tijana Djukic; Nenad Filipovic; V Название: Computational Medicine in Data Mining and Modeling ISBN: 1461487846 ISBN-13(EAN): 9781461487845 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The authors focus on applying data mining to the medical domain, including mining the sets of clinical data typically found in patient`s medical records, image mining, medical mining, data mining and machine learning applied to generic genomic data and more.
Автор: Girish Kumar Gupta, Mohammad Hassan Baig Название: In Silico Chemistry and Biology: Current and Future Prospects ISBN: 3110495171 ISBN-13(EAN): 9783110495171 Издательство: Walter de Gruyter Рейтинг: Цена: 24165.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
In Silico Chemistry and Biology: Current and Future Prospects provides a compact overview on recent advances in this highly dynamic branch of chemistry. Various methods of protein modelling and computer-assisted drug design are presented, including fragment- and ligand-based approaches. Many successful practical applications of these techniques are demonstrated. The authors also look to the future and describe the main challenges of the field.
Автор: Petr N. Vabishchevich Название: Computational Technologies: Advanced Topics ISBN: 3110359944 ISBN-13(EAN): 9783110359947 Издательство: Walter de Gruyter Цена: 9288.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses questions of numerical solutions of applied problems on parallel computing systems. Nowadays, engineering and scientific computations are carried out on parallel computing systems, which provide parallel data processing on a few computing nodes. In the development of up-to-date applied software, this feature of computers must be taken into account for the maximum efficient usage of their resources. In constructing computational algorithms, we should separate relatively independent subproblems in order to solve them on a single computing node.
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