Описание: This book gathers the main international research findings on non-steroidal anti-inflammatory drugs (NSAIDs) as emerging contaminants in water.
Описание: Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly prescribed groups of drugs in the community. There exists at present a conflict between the pharmaceutical industry with its attempts to introduce new NSAIDs and drug regulatory authorities who are generally not convinced of the need for additional drugs of_ this class.
Описание: Non-steroidal anti-inflammatory drugs (NSAIDs) are among the mostfrequently- prescribed drugs in the Western world. During the past decade a large number of new compounds were marketed, some of which had to be withdrawn after a short while because of adverse drug reactions. These experiences led to an under- standing that a complete picture of the safety of these drugs can only be obtained after their introduction into the marketplace.
Differentmethods ofpost-marketing surveillance (PMS) serve as important tools for monitoring the frequency of adverse reactions and for generating and corroborating hypotheses. Experience with PMS has thusfar been quite limited in Germany. In 1987 a non-profit organization, "Verein zur Langzeituntersuchung von Arzneimittel- wirkungen auf dem Gebiet der Rheumatologie e.
V. " (VLAR) was founded by interested physicians and pharmacologists to raise funds and perform investiga- tions on the safety of NSAIDs. The first project by the VLAR, SPALA ("Safety Profile of Antirheumatics in Long-Term Administration"), was sponsored by F.
Hoffmann-La Roche AG (Basel, Switzerland). In July 1990, when the project was successfully terminated, almost 30,000 patients had been completely docu- mented and their medical records entered into a computer for subsequent review by a select panel of experts with experience in monitoring adverse reactions to NSAIDs. The comments, criticisms, and ideas of these experts were brought togetherat a symposium organized by the VLAR at the Klinikum Steglitz (Berlin, Germany) on 12 October 1990.
Описание: AComprehensive Guide to Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) begins by describing the general characteristics, classification, pharmacokinetics, pharmacodynamics, clinical uses and adverse effects of NSAIDs. The adverse effects of NSAIDs, drug interactions and their clinical applications in neurological diseases, headaches, and cerebrovascular diseases are discussed. These drugs are also often used in dermatology, especially in the treatment of dermatosis. Extensive information concerning NSAIDs and dermatological diseases is provided. A broad perspective on the role of NSAIDs in infectious diseases is also provided. The next chapter discusses findings concerning the effects of NSAIDs on bone and tendon healing, together with cellular and molecular factors. The authors suggest that NSAIDs may be a risk factor for tissue healing. Diclofenac sodium (DS), widely used in urology clinics, exhibits dose-dependent side effects on various systems. This chapter suggests that nanoparticle technology can be applied to the oral form of DS in order to reduce its side-effects. The effects of NSAIDs on the reproductive systems of both sexes are also evaluated. Both genders make extensive use of NSAIDs during infertility treatment. Another chapter focuses on how DS affects spermatogenesis. The authors suggest that DS causes histopathological changes in the testes by disrupting the nutrition of testicular cells and impairing complete testis functions. Men wishing to have children should therefore use this drug with caution. The authors also review the effects of NSAIDs on prostatitis, benign prostatic hyperplasia and prostate cancer. In the following chapter, the authors examine the role of NSAIDs in gynaecology and obstetrics. Advances in the use of NSAIDs and melatonin in reproductive medicine for both sexes are discussed. The authors describe the biological roles of NSAIDs and melatonin in human reproduction, diseases, pregnancy, and assisted reproductive treatment. The subsequent chapter highlights the side-effects of NSAIDs on the gastrointestinal system. This book goes on to assess how DS affects the nervous system in the light of molecular and cellular analysis. The authors first explore the dose-dependent effects of DS on the nervous system. They then examine the potential neuroprotective / neurotoxic effects of DS on the nervous system, including the spinal cord, brain, cerebellum and peripheral nerves. The effects of DS on the adult hippocampus are assessed based on experimental studies. The purpose of this section is to highlight the relationship between oxidative stresses and the role of antioxidants in reducing DS toxicity. The importance of melatonin administration against pre- and postnatal DS toxicity in the nervous system is evaluated in several chapters. Recent findings suggest that prenatal exposure to NSAIDs causes an alteration in the morphology of optic nerve fibres based on stereological, histological and electron microscopic analysis. The authors evaluate histomorphometric results from light and electron microscopic analysis of the effects of prenatal DS exposure on male fertility. Numerous studies have shown that all elements of the male system are affected by this exposure. Lastly, the authors specifically focus on Sertoli cells and suggest that prenatal DS exposure produces toxic effects on Sertoli cell morphology.
Описание: The purpose of this book is to provide a comprehensive source of information regarding NSAIDs in detail. NSAIDs are widely used and prescribed to all age groups. This book represents a new approach for undergraduate and post-graduate medical students of all specialties. The book was written in simple and easily understandable language for everyone. This book is mainly focused on NSAIDs and related topics like mechanism and pharmacological actions, adverse drug reactions, fixed dose combinations, poisoning of overdose, usage in neurological conditions, geriatrics, paediatrics and pregnancy, NSAID-induced gastropathy and nephropathy, NSAIDs in oncology, pharmacogenomics, and in COVID. Their use is associated with a vast spectrum of adverse drug effects, so drug selection is crucial in various conditions. Each chapter of the book presents the pharmacology of NSAIDs in the framework of biochemical, physiologic or pathophysiological systems. Each topic provides an understanding of the basic concepts of NSAIDs on already existing and on newer drugs and their pharmacological use in various organ systems at different age groups. Updated and recent information including the use of NSAIDs in COVID has been added. Detailed drug information in aspects of drug selection and its contraindications as per patients disease status and updated approaches in newer clinical perspectives were included. Diagrams, tables, and flowcharts are included to make the concepts easier to understand. At the end of each chapter, useful references are added for further reading.
Автор: Mishra, Ajay Kumar Название: Emerging and nanomaterial contaminants in wastewater ISBN: 0128146737 ISBN-13(EAN): 9780128146736 Издательство: Elsevier Science Рейтинг: Цена: 27791.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Emerging and Nanomaterial Contaminants in Wastewater: Advanced Treatment Technologies describes the state-of-the-art of remediation technologies, such as those involving nanotechnology, filtration devices (e.g. membranes), strategies involving adsorption and precipitation processes, development of new sorbents, nanosorbents, biosorbents, green technology, bio-electrokinetics, degradation of pollutants, advanced oxidative process, oxidative electrochemical and photocatalytic processes, catalytic degradation, and emerging hybrid technologies, such as photocatalyst membrane photoreactors using TiO2. Scientists and researchers in academia and industry will benefit from this comprehensive resource on the fundamental science behind the mechanisms at which wastewater sources can be purified from emerging contaminants.
Provides a fundamental understanding of emerging contaminants to help readers select appropriate remediation technologies
Discusses, in detail, new and advanced green technologies that remove emerging contaminants from wastewater
Shows how to ensure water quality and save public health by protecting water resources from contaminants
Описание: The indiscriminate use of chemical substances in industrial processes and anthropogenic activities, have resulted in the release of these compounds into aquatic ecosystems through municipal, hospital and industrial discharges, producing various undesired effects on the environment and on species of ecological interest. These compounds, such as metals, pesticides, emerging pollutants and other substances are persistent and susceptible to biotic and/or abiotic transformations, yielding metabolites that can be more toxic than the original compounds. In this book, researchers from diverse environmental science disciplines share their experiences in countries such as Argentina, Brazil, Colombia and Mexico, and critically examine the problem of contaminants in aquatic ecosystems in Latin America, as well as the risks presented by their presence.
Автор: Kraus Johanna M., Walters David M., Mills Marc A. Название: Contaminants and Ecological Subsidies: The Land-Water Interface ISBN: 3030494799 ISBN-13(EAN): 9783030494797 Издательство: Springer Цена: 16769.00 р. Наличие на складе: Поставка под заказ.
Описание: This volume explores the effects of aquatic contaminants on ecological subsidies and food web exposure at the boundary of aquatic and terrestrial ecosystems.
Автор: Morin-Crini Nadia, Lichtfouse Eric, Crini Grйgorio Название: Emerging Contaminants Vol. 1: Occurrence and Impact ISBN: 3030690784 ISBN-13(EAN): 9783030690786 Издательство: Springer Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Emerging contaminants, therefore, include a large number of both recently discovered and well-known compounds such as rare earth elements, viruses, bacteria, nanomaterials, microplastics, pharmaceuticals, endocrine disruptors, hormones, personal care products, cosmetics, pesticides, surfactants and industrial chemicals.
Автор: Hernandez-Maldonado, Arturo Название: Contaminants of Emerging Concern in Water and Wastewater ISBN: 0128135611 ISBN-13(EAN): 9780128135617 Издательство: Elsevier Science Рейтинг: Цена: 26107.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Contaminants of Emerging Concern in Water and Wastewater: Advanced Treatment Processes presents the state-of-the-art in the design and use of adsorbents, membranes, and UV/oxidation processes, and the challenges that will need to be addressed to close the gap between development and implementation in water/wastewater treatment applications.
This book contains information related to: adsorbent and membrane design and performance; direct comparison of performance data between new (inorganic and metal organic nanoporous materials) and classic adsorbents and membranes; list of advantages, disadvantages, and challenges related to performance limitations, regenerability, and upscaling; identification of potential site and off-site applications according to adsorbent and membrane types; transformation of CECs in low- and/or medium-pressure UV irradiation processes used for disinfection; oxidation of CECs by chlorine and ozone; and, comparison of advanced oxidation processes for treatment of a variety of CECs in water and wastewater.
Addresses the advantages/disadvantages of select technologies, including energy resources needs and waste management issues of reverse osmosis among other issues applicable to adsorption and oxidation systems
Present information on the advancements of technology within the realm of "Engineered Treatments of CECs"
Focuses on the inherent science and technology of advanced treatment processes, which readers will be able to apply fundamental principles to various classes of CECs
Описание: The indiscriminate use of chemical substances in industrial processes and anthropogenic activities, have resulted in the release of these compounds into aquatic ecosystems through municipal, hospital and industrial discharges, producing various undesired effects on the environment and on species of ecological interest.
Описание: A major issue that has remained prevalent in today's modern world has been the presence of chemicals within water sources that the public uses for drinking. The associated health risks that accompany these contaminants are unknown but have sparked serious concern and emotive arguments among the global community. Empirical research is a necessity to further understand these contaminants and the effects they have on the environment. Effects of Emerging Chemical Contaminants on Water Resources and Environmental Health is a pivotal reference source that provides vital research on current issues regarding the occurrence, toxicology, and abatement of emerging contaminants in water sources. While highlighting topics such as remediation techniques, pollution minimization, and technological developments, this publication explores sample preparation and detection of these chemical contaminants as well as policy and legislative issues related to public health. This book is ideally designed for environmental engineers, biologists, health scientists, researchers, students, and professors seeking further research on the latest developments in the detection of water contaminants.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
