This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Kavanagh Название: Fungi: Biology and Applications 3e ISBN: 1119374324 ISBN-13(EAN): 9781119374329 Издательство: Wiley Рейтинг: Цена: 12081.00 р. 17258.00-30% Наличие на складе: Есть (1 шт.) Описание:
Fungi: Biology and Applications was first published in 2005 and since that date has sold over 1500 copies. The second edition was published in 2011 and has sold in excess of 750 copies and has also been translated into Turkish (total sales of two editions >2500 copies). This book has been extremely successful and is a recommended text in many third level institutions. The book is designed to appeal to undergraduate students and to those working with fungi for the first time (e.g. postgraduates, industrial scientists). Traditionally, fungal book have been very specific but this book provides chapters on a wide range of areas at a level sufficient for undergraduate and postgraduate study. For example chapters cover topics such as physiology, genetics, proteomics, medical mycology, plant pathology, genomic, and antifungal therapy. The provision of revision questions and extra reading at the end of each chapter also facilitates the learning process.
The third edition is warranted to take account of recent developments in a wide range of areas. For example new developments in proteomics and genomics are revolutionizing our understanding of fungi and their interaction with the environment and/or the host. Antifungal drug resistance is emerging as a major problem in the treatment of fungal infections. New fungal pathogens of plants are emerging as problems in temperate parts of the World due to the effect of climate change.
In addition to updating and revising the chapters in the second edition three new chapters will be included in the new edition: Fungi as food, Fungi and the immune response and Fungi in the environment. These further broaden the scope of the book.
An updated edition is now warranted to take account of recent developments in fungal biology. Many existing books in this area are subject specific whereas this book covers a wide range of topics. The addition of extra chapters in areas such as Fungi and food, Fungi and the immune system and Fungi in the environment broadens the appeal of the book and means that the reader now has a book covering all of the main areas of fungal biology thus making this book an essential addition to microbiology libraries. The book will be an excellent resource for undergraduate microbiology students and also for those working with fungi in Industry or Academia.
Автор: Lieberman Jay R., Friedlaender Gary E. Название: Bone Regeneration and Repair / Biology and Clinical Applications ISBN: 0896038475 ISBN-13(EAN): 9780896038479 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.
Автор: Carter Название: Virology - Principles and Applications 2e ISBN: 1119991420 ISBN-13(EAN): 9781119991427 Издательство: Wiley Рейтинг: Цена: 8387.00 р. Наличие на складе: Поставка под заказ.
Описание: The second edition of Virology is an accessible introduction designed to enable students to understand the principles of virus structure, replication and genetics. The aim of this book is to help the reader appreciate the relevance of virology in the modern world, including the fields of vaccines, anti-viral drugs and cancer.
Описание: This book introduces the emerging perspective of collision dynamics in mammalian terrestrial locomotion and explain how it influences the interpretation of form and functional capabilities. The coverage brings the reader to a sophisticated conceptual understanding of the relevant mechanics and the current debate ongoing in the field.
Название: Fenugreek ISBN: 0367395908 ISBN-13(EAN): 9780367395902 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Fenugreek presents an in-depth review on the genus Trigonella, with an emphasis on the species T. foenum-graecum L. (fenugreek). Written by experts, the book discusses the chemical constituents of the species of Trigonella, their pharmacological properties, and the marketing of fenugreek seed. It includes chapters describing the genus' botany, physiology, cultivation, breeding, nutrition, pest-disease, and weed control, as well as a detailed presentation on the usefulness of fenugreek seed as food, spice, perfume. This book is ideal for those concerned with the study, cultivation, and use of medicinal and aromatic plants, and particularly of fenugreek.
Описание: This textbook is aimed at newcomers to nonlinear dynamics and chaos, especially students taking a first course in the subject. The presentation stresses analytical methods, concrete examples, and geometric intuition. The theory is developed systematically, starting with first-order differential equations and their bifurcations.
Автор: Burns Malcolm, Foster Lucy, Walker Michael Название: DNA Techniques to Verify Food Authenticity: Applications in Food Fraud ISBN: 1788011783 ISBN-13(EAN): 9781788011785 Издательство: Royal Society of Chemistry Рейтинг: Цена: 31469.00 р. Наличие на складе: Поставка под заказ.
Описание: Providing the most comprehensive and timely collection of material from those working at the forefront of DNA techniques applied to food authenticity, this book will appeal to food testing laboratories worldwide and food policy professionals and regulatory organisations who will be using these techniques to back up legislation and regulation.
Автор: Huimin Zhao Название: Protein Engineering: Tools and Applications ISBN: 3527344705 ISBN-13(EAN): 9783527344703 Издательство: Wiley Рейтинг: Цена: 23594.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
A one-stop reference that reviews protein design strategies to applications in industrial and medical biotechnology
Protein Engineering: Tools and Applications is a comprehensive resource that offers a systematic and comprehensive review of the most recent advances in the field, and contains detailed information on the methodologies and strategies behind these approaches. The authors--noted experts on the topic--explore the distinctive advantages and disadvantages of the presented methodologies and strategies in a targeted and focused manner that allows for the adaptation and implementation of the strategies for new applications.
The book contains information on the directed evolution, rational design, and semi-rational design of proteins and offers a review of the most recent applications in industrial and medical biotechnology. This important book:
Covers technologies and methodologies used in protein engineering
Includes the strategies behind the approaches, designed to help with the adaptation and implementation of these strategies for new applications
Offers a comprehensive and thorough treatment of protein engineering from primary strategies to applications in industrial and medical biotechnology
Presents cutting edge advances in the continuously evolving field of protein engineering
Written for students and professionals of bioengineering, biotechnology, biochemistry, Protein Engineering: Tools and Applications offers an essential resource to the design strategies in protein engineering and reviews recent applications.
Описание: A unique book that summarizes the properties, toxicology, and biomedical applications of TiO2-based nanoparticles Nanotechnology is becoming increasingly important for products used in our daily lives. Nanometer-sized titanium dioxide (TiO2) are widely used in industry for different purposes, such as painting, sunscreen, printing, cosmetics, biomedicine, and so on. This book summarizes the advances of TiO2 based nanobiotechnology and nanomedicine, covering materials properties, toxicological research, and biomedical application, such as antibacter, biosensing, and cancer theranostics.
It uniquely integrates the TiO2 applications from physical properties, toxicology to various biomedical applications, and includes black TiO2 based cancer theranostics. Beginning with a comprehensive introduction to the properties and applications of nanoparticles, TiO2 Nanoparticles: Applications in Nanobiotechnology, Theranostics and Nanomedicine offers chapters on: Toxicity of TiO2 Nanoparticles; Antibacterial Applications of TiO2 Nanoparticles; Surface Enhanced Raman Spectrum of TiO2 Nanoparticle for Biosensing (TiO2 Nanoparticle Served as SERS Sensing Substrate); TiO2 as Inorganic Photosensitizer for Photodynamic Therapy; Cancer Theranostics of Black TiO2 Nanoparticles; and Neurodegenerative Disease Diagnostics and Therapy of TiO2-Based Nanoparticles. This title: -Blends the physical properties, toxicology of TiO2 nanoparticles to the many biomedical applications -Includes black TiO2 based cancer theranostics in its coverage -Appeals to a broad audience of researchers in academia and industry working on nanomaterials-based biosensing, drug delivery, nanomedicine TiO2 Nanoparticles: Applications in Nanobiotechnology, Theranostics and Nanomedicine is an ideal book for medicinal chemists, analytical chemists, biochemists, materials scientists, toxicologists, and those in the pharmaceutical industry.
Название: Medical applications of artificial intelligence ISBN: 1138072273 ISBN-13(EAN): 9781138072275 Издательство: Taylor&Francis Рейтинг: Цена: 11789.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Enhanced, more reliable, and better understood than in the past, artificial intelligence (AI) systems can make providing healthcare more accurate, affordable, accessible, consistent, and efficient. However, AI technologies have not been as well integrated into medicine as predicted. In order to succeed, medical and computational scientists must develop hybrid systems that can effectively and efficiently integrate the experience of medical care professionals with capabilities of AI systems.
After providing a general overview of artificial intelligence concepts, tools, and techniques, Medical Applications of Artificial Intelligence reviews the research, focusing on state-of-the-art projects in the field. The book captures the breadth and depth of the medical applications of artificial intelligence, exploring new developments and persistent challenges.
Описание: This book focuses on state-of-the-art microfluidic research in medical and biological applications. The top-level researchers in this research field explain carefully and clearly what can be done by using microfluidic devices. Beginners in the field —undergraduates, engineers, biologists, medical researchers—will easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. The book covers many interesting subjects, including cell separation, protein crystallization, single-cell analysis, cell diagnosis, point-of-care testing, immunoassay, embyos/worms on a chip and organ-on-a-chip. Readers will be convinced that microfluidic devices have great potential for medical and biological applications.
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