Aging: Exploring a Complex Phenomenon, Ahmad Shamim I.

Автор: Lim Ramon
Название: Self And The Phenomenon Of Life: A Biologist Examines Life From Molecules To Humanity
ISBN: 9813203773 ISBN-13(EAN): 9789813203778
Издательство: World Scientific Publishing
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Цена: 9821.00 р.
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Описание: 'As an innovative treatment of scientific topics with philosophical undertones, this is an impressive work, Some may not be convinced by the arguments, but for scientists and philosophers alike the author presents a thesis worth exploring.'CHOICEThe book describes a common ground between the biology of life and the humanity of life without compromising either discipline. It attempts to bridge the gap between our 'two cultures' -- the sciences and the humanities, as advocated by C P Snow fifty years ago. This book connects our meager existence to the entire living world and the universe, physically and spiritually, through the simple perspective of 'self, ' being defined as a system that seeks its own perpetuation.

Автор: Lim Ramon
Название: Self And The Phenomenon Of Life: A Biologist Examines Life From Molecules To Humanity
ISBN: 9813203781 ISBN-13(EAN): 9789813203785
Издательство: World Scientific Publishing
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Цена: 5069.00 р.
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Описание: 'As an innovative treatment of scientific topics with philosophical undertones, this is an impressive work, Some may not be convinced by the arguments, but for scientists and philosophers alike the author presents a thesis worth exploring.'CHOICEThe book describes a common ground between the biology of life and the humanity of life without compromising either discipline. It attempts to bridge the gap between our 'two cultures' -- the sciences and the humanities, as advocated by C P Snow fifty years ago. This book connects our meager existence to the entire living world and the universe, physically and spiritually, through the simple perspective of 'self, ' being defined as a system that seeks its own perpetuation.

Автор: William J. Brown
Название: The Golgi Complex
ISBN: 1493964615 ISBN-13(EAN): 9781493964611
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Focusing on new methods and techniques developed to address longstanding questions about the Golgi complex, this volume explores a diverse set of chapters, ranging from live and fixed cell imaging techniques to in vitro biochemical reconstitution systems.

Автор: Bairong Shen
Название: Bioinformatics for Diagnosis, Prognosis and Treatment of Complex Diseases
ISBN: 9400779747 ISBN-13(EAN): 9789400779747
Издательство: Springer
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Цена: 20896.00 р.
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Описание: The book introduces the bioinformatics tools, databases and strategies for the translational research, focuses on the biomarker discovery based on integrative data analysis and systems biological network reconstruction.

Автор: Sharpe
Название: Stereoselective Desymmetrization Methods in the Assembly of Complex Natural Molecules
ISBN: 3319390244 ISBN-13(EAN): 9783319390246
Издательство: Springer
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Цена: 19591.00 р.
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Описание: This thesis describes the inception, design, and implementation of stereoselective desymmetrization reactions in the total synthesis of the natural products pactamycin and paspaline. In the case of pactamycin, the author develops a novel asymmetric Mannich reaction and symmetry-breaking reduction strategy to enable facile construction of the complex core architecture in fifteen steps using commercially available materials – the shortest synthesis to date. He subsequently demonstrates the flexibility of this approach in SAR investigations by highlighting the preparation of twenty-five unique pactamycin structural congeners. For paspaline, the author develops a biocatalytic desymmetrization strategy that allows the highly controlled synthesis of core stereochemistry and provides a platform for the development of new conceptual disconnections in the synthesis of 'steroid-like' natural products. This thesis offers a valuable resource for students embarking on a PhD in total synthesis.

Автор: Rensberger, Boyce
Название: Life Itself Exploring the Realm of the Living Cell (Paperback)
ISBN: 0195125002 ISBN-13(EAN): 9780195125009
Издательство: Oxford Academ
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Цена: 2770.00 р.
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Описание: In Life Itself, Boyce Rensberger takes readers to the frontlines of cell research with some of the brightest investigators in molecular, cellular, and developmental biology. Virtually all the hottest topics in biomedical research are covered here, such as how do cells and their minute components move? How do the body`s cells heal wounds? What is cancer? Why do cells die? And what is the nature of life? Readers will discover that cells teem with activity andthat, inside, they `are more crowded with components than the inside of a computer`.

Автор: Kasirajan Ayyanathan
Название: Epigenetics and Pathology: Exploring Connections Between Genetic Mechanisms and Disease Expression
ISBN: 1926895789 ISBN-13(EAN): 9781926895789
Издательство: Taylor&Francis
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Цена: 20671.00 р.
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Описание:

This title includes a number of Open Access chapters.

Автор: Maria Teresa Tatto; Michael C. Rodriguez; Wendy M.
Название: Exploring the Mathematical Education of Teachers Using TEDS-M Data
ISBN: 3030063720 ISBN-13(EAN): 9783030063726
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book uses the publicly available TEDS-M data to answer such questions as: How does teacher education contribute to the learning outcomes of future teachers? Are there programs that are more successful than others in helping teachers learn to teach mathematics? How does the local and national policy environment contribute to teacher education outcomes? It invites readers to explore these questions across a large number of international settings.The importance of preparing future mathematics teachers has become a priority across many nations. Across the globe nations have allocated resources and expertise to this endeavour. Yet in spite of the importance accorded to teacher education not much is known about different approaches to preparing knowledgeable teachers and whether these approaches do in fact achieve their purpose. The Mathematics Teacher Education and Development Study (TEDS-M) is the first, and to date the only, cross-national study using scientific and representative samples to provide empirical data on the knowledge that future mathematics teachers of primary and secondary school acquire in their teacher education programs. The study addresses the central importance of teacher knowledge in learning to teach mathematics by examining variation in the nature and influence of teacher education programs within and across countries.The study collected data on teacher education programs structure, curriculum and opportunities to learn, on teacher educators’ characteristics and beliefs, and on future mathematics teachers’ individual characteristics, beliefs, and mathematics and pedagogical knowledge across 17 countries providing a unique opportunity to explore enduring questions in the field.

Автор: Susan Buchanan; Nicholas Noinaj
Название: The BAM Complex
ISBN: 1493949209 ISBN-13(EAN): 9781493949205
Издательство: Springer
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Цена: 13275.00 р.
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Описание:

1. The β-barrel Assembly Machinery Complex

Denisse L. Leyton, Matthew J. Belousoff, and Trevor Lithgow

2. Yeast Mitochondria as a Model System to Study the Biogenesis of Bacterial β-barrel Proteins

Thomas Ulrich, Philipp Oberhettinger, Ingo B. Autenrieth, and Doron Rapaport

3. Experimental Methods for Studying the BAM Complex in Neisseria meningitidis

Martine P. Bos, Ria Tommassen-van Boxtel, and Jan Tommassen

4. Heat Modifiability of Outer Membrane Proteins from Gram-Negative Bacteria

Nicholas Noinaj, Adam J. Kuszak, and Susan K. Buchanan

5. The Role of a Destabilized Membrane for OMP Insertion

Ashlee M. Plummer, Dennis Gessmann, and Karen G. Fleming

6. Treponema pallidum in Gel Microdroplets: A Method for Topological Analysis of BamA (TP0326) and Localization of Rare Outer Membrane Proteins

Amit Luthra, Arvind Anand, and Justin D. Radolf

7. Analyzing the Role of Periplasmic Folding Factors in the Biogenesis of OMPs and Members of the Type V Secretion System

Gustavo Bodelуn, Elvira Marнn, and Luis Бngel Fernбndez

8. An In Vitro Assay for Substrate Translocation by FhaC in Liposomes

Enguo Fan, Derrick Norell, and Matthias Mьller

9. Measuring Cell-cell Binding Using Flow-Cytometry

Zachary C. Ruhe, Christopher S. Hayes, and David A.

Автор: M. Kasahara
Название: Major Histocompatibility Complex
ISBN: 443165870X ISBN-13(EAN): 9784431658702
Издательство: Springer
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Цена: 16979.00 р.
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Описание: It covers diverse topics pertinent to MHC evolution, including the origin of the adaptive immune system, the organi- zation of the MHC in humans and other model vertebrates, MHC-parasite co- evolution, and the nature and origin of MHC polymorphism.

Автор: Leonid Sazanov
Название: A Structural Perspective on Respiratory Complex I
ISBN: 9401783349 ISBN-13(EAN): 9789401783347
Издательство: Springer
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Цена: 25155.00 р.
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Описание: The book contains chapters written by leaders in the research on the structure and function of respiratory complex I. It will provide a concise and authoritative summary of the current knowledge on complex I of respiratory chains. This enzyme is central to energy metabolism and is implicated in many human neurodegenerative diseases, as well as in aging. Until recently it was poorly understood on a structural level, and this book will provide a timely reference resource. Such a book was not published previously. The last time a minireview series on complex I were published was in 2001, and since then complex I field changed quite dramatically.

Название: Complex Flavoproteins, Dehydrogenases and Physical Methods: Volume 2 Complex Flavoproteins, Dehydrogenases and Physical Methods
ISBN: 3110298287 ISBN-13(EAN): 9783110298284
Издательство: Walter de Gruyter
Цена: 31603.00 р.
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Описание: The dynamic field of flavin and flavoprotein biochemistry has seen rapid advancement in recent years. This comprehensive two volume set provides an overview of all aspects of contemporary research in this important class of enzymes. Topics treated include flavoproteins involved in energy generation, signal transduction and electron transfer (including respiration); oxygen activation by flavoproteins; the biology and biochemistry of complex flavoproteins; flavin and flavoprotein photochemistry/photophysics as well as biotechnological applications of flavoproteins. Recent developments in this field include new structures (including those of large membrane-integral electron transfer complexes containing FMN or FAD), elucidation of the role of flavoproteins in cell signalling pathways (including both phototaxis and the circadian cycle) and important new insights into the reaction mechanisms of flavin-containing enzymes. This volume focusing on complex flavoproteins and physical methods is an essential reference for all researchers in biochemistry, chemistry, photochemistry and photophysics working on flavoenzymes.