Автор: Teunissen Charlotte E., Zetterberg Henrik Название: Cerebrospinal Fluid Biomarkers ISBN: 1071613189 ISBN-13(EAN): 9781071613184 Издательство: Springer Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.
Автор: Payne, Jennifer L. Название: Biomarkers Of Postpartum Psychiatric Disorders ISBN: 0128155086 ISBN-13(EAN): 9780128155080 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Biomarkers of Postpartum Psychiatric Disorders provides an up-to-date reference on the current research relating to biomarkers in psychiatric disorders, including major depressive disorder, OCD and bipolar disorder in the immediate postpartum time-period. It is the only reference on the market that synthesizes and interprets available data and reviews clinical phenotypes. Topics cover hormonal contributions, immunology, epigenetics and neuroimaging. While the risk of psychiatric illness during pregnancy appears to be equivalent to the risk at any other time in a woman's life, the risk in the immediate postpartum time period is dramatically increased, hence the importance of the discussions in this title.
Автор: Alexey Moskalev Название: Biomarkers of Human Aging ISBN: 3030249697 ISBN-13(EAN): 9783030249694 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging.In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function).The book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging.Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.
Автор: Romero-Gomez Название: NAFLD and NASH ISBN: 3030371727 ISBN-13(EAN): 9783030371722 Издательство: Springer Рейтинг: Цена: 11878.00 р. Наличие на складе: Поставка под заказ.
Описание:
This book provides a comprehensive overview of the diagnosis and management of Non-alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatis (NASH). Basic principles of disease progression, the genetic and nutritional basis of NAFLD and NASH are explained along with the proteomic principles underlying biomarker development. Chapters cover both biochemical and imaging biomarkers used in elastrography and ultrasound and discuss how these are applicable to early diagnosis and monitoring of NASH and NAFLD.
This is a useful resource for hepatologists, primary care providers with an interest in metabolic disease, diabetologists and endocrinologists in their daily clinical practice.
Описание: Proceedings of a NATO ARW held in Luso, Portugal, June 1-5, 1992
Автор: Magdalena Thurin; Alessandra Cesano; Francesco M. Название: Biomarkers for Immunotherapy of Cancer ISBN: 1493997726 ISBN-13(EAN): 9781493997725 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Поставка под заказ.
Описание: This book provides the immune oncology (IO) community with a deeper understanding of the scope of the biomarker methods to potentially improve the outcome from immunotherapy. The editors secured the input from experts in the field dedicated to translating scientific research from bench to bedside was submitted. The book provides not only details about the technical, standardization and interpretation aspects of the methods but also introduces the reader to the background information and scientific justification for selected biomarkers and assays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Описание: This book develops and details a rigorous, canonical modeling approach for analyzing spatio-temporal brain wave dynamics. The nonlinear, nonstationary behavior of brain wave measures and general uncertainty associated with the brain makes it difficult to apply modern system identification techniques to such systems. While there is a substantial amount of literature on the use of stationary analyses for brain waves, relatively less work has considered real-time estimation and imaging of brain waves from noninvasive measurements. This book addresses the issue of modeling and imaging brain waves and biomarkers generally, treating the nonlinear and nonstationary dynamics in near real-time. Using a modal state-space formulation leads to intuitive, physically significant models which are used for analysis and diagnosis. A Modal Approach to the Space-Time Dynamics of Cognitive Biomarkers provides a much-needed reference for practicing researchers in biomarker modeling leveraging the lens of engineering dynamics.
Автор: Moskalev Alexey Название: Biomarkers of Human Aging ISBN: 3030249727 ISBN-13(EAN): 9783030249724 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging. In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function). The book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging. Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.
Автор: Philip V. Peplow; Bridget Martinez; Svetlana A. Da Название: Stroke Biomarkers ISBN: 1493996843 ISBN-13(EAN): 9781493996841 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Поставка под заказ.
Описание: This volume presents the latest data on recent achievements in new and emerging technologies for stroke biomarkers and innovations in stroke assessment.
Автор: Daniela Galimberti; Elio Scarpini Название: Neurodegenerative Diseases ISBN: 1447172426 ISBN-13(EAN): 9781447172420 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer`s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases.
Автор: Peplow Название: Stroke Biomarkers ISBN: 1493996819 ISBN-13(EAN): 9781493996810 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Поставка под заказ.
Описание: This volume presents the latest data on recent achievements in new and emerging technologies for stroke biomarkers and innovations in stroke assessment.
Автор: Farooqui, Akhlaq A. Название: Neurochemical Aspects of Alzheimer Disease ISBN: 0128099372 ISBN-13(EAN): 9780128099377 Издательство: Elsevier Science Рейтинг: Цена: 13298.00 р. Наличие на складе: Поставка под заказ.
Описание:
Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists, and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders.
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