Автор: John Glasby Название: Encyclopedia of the Alkaloids ISBN: 146158809X ISBN-13(EAN): 9781461588092 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Volume 3 of the Encyclopedia of the Alkaloids covers the literature to the end of October 1976 and includes a large number of these compounds which have been discovered since the first two volumes were published in 1975.
Автор: Brian Robinson Название: The Calabar Bean and its Alkaloids ISBN: 9402411909 ISBN-13(EAN): 9789402411904 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Investigations into Calabar beans (the dried ripe seeds of Physostigma venenosum) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoing at the forefront of chemical and medical discovery. Those in particular involving its major such component, l-physostigmine, have led to an understanding of some of the fundamental mechanisms occurring in physiology, pharmacology and biochemistry and, either actually or potentially (by providing a template and thereby acting as a “lead compound”) have provided a useful treatment for a variety of neurological disorders associated with irregularities in cholinergic transmission in which augmentation of cholinergic activity has proved to be beneficial. Physostigma venenosum is distributed throughout equatorial West Africa and having a colourful history – by virtue of their former use as an ordeal poison in trials for witchcraft in the Efik society of Old Calabar – are its dried ripe seeds (Calabar beans). The major toxic compound isolated from these, l-physostigmine, which is also known as eserine and is the only alkaloid as yet also to be isolated from a microbial source (along with l-N(8)-norphysostigmine) and is the first alkaloid found to contain a 1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole ring system, and the first natural product found to contain a carbamyl group. It also became one of the first examples whereby the mechanism of action of a drug could be defined at the molecular level relatively simply, played a crucial role in the Nobel Prize – winning discovery of the mechanism of neurohumoral transmission, and has led to products for the treatment of a wide range of disorders associated with deficiencies in cholinergic transmission. Several other alkaloids have also been isolated from the Calabar bean. For some of these, structures have been established, syntheses effected and pharmacology investigated.
Описание: This book explores efficient syntheses of indole alkaloids based on gold-catalyzed cascade cyclizations, presenting two strategies for total synthesis of these natural products based on gold-catalyzed reactions of conjugated diyne or ynamide.
Описание: This book explores efficient syntheses of indole alkaloids based on gold-catalyzed cascade cyclizations, presenting two strategies for total synthesis of these natural products based on gold-catalyzed reactions of conjugated diyne or ynamide.
Описание: Elizabeth Gaskell`s Life of Charlotte Bronte (1857) is a pioneering biography of one great Victorian woman novelist by another. This edition is based on the Third Edition of 1857, revised by Gaskell and collated with the manuscript and the previous two editions, as well as with Charlotte Bronte`s letters, offering fuller information about the process of composition than any previous edition.
Автор: Jiaju Zhou Название: Alkaloids, Part 2 ISBN: 3110653621 ISBN-13(EAN): 9783110653625 Издательство: Walter de Gruyter Цена: 32254.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This 8-volume set provides a systematic description on 8,350 active marine natural products from 3,025 various kinds of marine organisms. The diversity of structures, biological resources and pharmacological activities are discussed in detail. Molecular structural classification system with 264 structural types are developed. The 4th volume continuously illustrates the molecular formula and structures of alkaloids.
Автор: Knolker, Hans-Joachim Название: The Alkaloids,84 ISBN: 0128209828 ISBN-13(EAN): 9780128209820 Издательство: Elsevier Science Рейтинг: Цена: 30318.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The Alkaloids, Volume 84, is the newest release in a series that has covered the topic for more than 60 years. As the esteemed, leading reference in the field of alkaloid chemistry, this series covers all aspects of alkaloids, including their chemistry, biology and pharmacology. Sections are presented as high-quality, timeless reviews written by renowned experts in the field.
Автор: Knolker, Hans-Joachim Название: The Alkaloids ISBN: 0128171510 ISBN-13(EAN): 9780128171516 Издательство: Elsevier Science Рейтинг: Цена: 25096.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The Alkaloids, Volume 81, the newest release in a series that has covered the topic for more than 60 years, covers all aspects of alkaloids, including their chemistry, biology and pharmacology. Sections in this new release cover Bisbenzylisoquinoline Alkaloids, Alkaloids of the Lauraceae, and The Chemical Synthesis and Applications of Tropane Alkaloids, amongst other topics.
Provides the latest information on the study of alkaloids
Covers their chemistry, biology, pharmacology and medical applications
Contains more than 70 published volumes in this interesting field of study
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