Factors Affecting Neurological Aging, Martin, Colin R.
Автор: Martin, Colin R. Название: Factors Affecting Neurodevelopment ISBN: 0128179864 ISBN-13(EAN): 9780128179864 Издательство: Elsevier Science Рейтинг: Цена: 32844.00 р. Наличие на складе: Поставка под заказ.
Описание: Help students with education recovery by resolving gaps in knowledge and understanding and addressing misconceptions in GCSE 9-1 Combined Science. This authoritative Teacher Resource Pack accompanies Secure Science for GCSE Workbook and digital support online and on mobile to support teachers through the intervention sessions.
Автор: Farooqui, Tahira Название: Trace Amines and Neurological Disorders ISBN: 0128036036 ISBN-13(EAN): 9780128036037 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors explores trace amines which, under normal conditions, are present in the mammalian brain and peripheral nervous tissues at very low (nanomolar) concentrations. However, in a diverse array of human pathologies ranging from substance abuse, depression, attention deficit hyperactivity disorder, eating disorders, schizophrenia, and other neurological and neuropsychiatric diseases, the levels of trace amines are unusually high with an imbalance in their functions. Furthermore, the rapid turnover of trace amines is evidenced by their dramatic increases following treatment with monoamine oxidase inhibitors (MAOI) or deletion of the MAO genes. This suggests that the concentration of trace amines may be considerably higher at neuronal synapses than predicted by steady-state measures, implicating some pathophysiological role. Therefore, understanding molecular mechanisms and developing selective agonists and antagonists for trace amine-associated receptors (TAARs) has become a good approach for treating these diseases. Although the effects of trace amines at low physiological concentrations in mammalian species have been difficult to demonstrate, they may serve to maintain the neuronal activity of other monoamine neurotransmitters by possessing postsynaptic modulatory effects, particularly dopamine and serotonin, within defined physiological limits. Such an effect of trace amines makes them ideal candidates for the development of novel therapeutics for a wide range of human disorders. This book presents up-to-date, cutting-edge, and comprehensive information on the link between trace amines and neurological disorders.
Автор: Watson, Ronald Ross Название: Physical Activity and the Aging Brain ISBN: 0128050942 ISBN-13(EAN): 9780128050941 Издательство: Elsevier Science Рейтинг: Цена: 15662.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Physical Activity and the Aging Brain: Effects of Exercise on Neurological Function is a complete guide to the manifold effects of exercise and physical activity on the aging brain. Cognitive decline and motor impairment, onset of diseases and disorders, and even changes in family structure and social settings that occur as we age can all impact activity levels, yet continued physical activity is crucial for successful neurological functioning.
This book examines the role that exercise and physical activity play in halting or modulating the deleterious effects of these numerous aging concerns by first examining the current state of research into how exercise manifests physical changes in the brain. It then discuss how physical activity combines with other lifestyle factors to benefit the aging brain, including nutrition, computerized brain training, and social engagement. Most significantly, it also covers how physical activity can serve as therapy to help alleviate the symptoms of various neurological diseases impacting aging populations, with particular emphasis on Alzheimer's disease and age-related cognitive decline.
The book provides broad coverage of the effects of exercise and physical activity on the aging brain, its therapeutic effects, and the many factors that influence the aging process.
Описание: Chapter 1. Peroxisome: metabolic functions and biogenesis.- Chapter 2. Peroxisomal Dysfunction and Oxidative Stress in Neurodegenerative Disease: A Bidirectional Crosstalk.- Chapter 3. 7-hydroxycholesterols-induced peroxisomal disorders in glial and microglial cells: potential role in neurodegeneration.- Chapter 4. Peroxisome biogenesis disorders.- Chapter 5. Fatty Acid Oxidation in Peroxisomes: Enzymology, Metabolic Crosstalk with Other Organelles And Peroxisomal Disorders.- Chapter 6. Zellweger syndrome disorders: from severe neonatal disease to atypical adult presentation.- Chapter 7. Heimler Syndrome.- Chapter 8. Potential involvement of peroxisome in multiple sclerosis and Alzheimer's disease.- Chapter 9. Developmental and degenerative cerebellar pathologies in peroxisomal β-oxidation deficiency.- Chapter 10. A mouse model system to study peroxisomal role in neurodegenerative diseases such as peroxisome biogenesis disorders.- Chapter 11. The Drosophila melanogaster as genetic model system to dissect the mechanisms of disease that lead to neurodegeneration in adrenoleukodystrophy.- Chapter 12. Human peroxisomal 3-keto-acyl-CoA thiolase: tissue expression and metabolic regulation.- Chapter 13. Biological functions of plasmalogens.- Chapter 14. Therapeutic efficacy of plasmalogens for Alzheimer's disease, Mild Cognitive Impairment and Parkinson's disease in conjunction with a new hypothesis for the etiology of Alzheimer's disease.
Автор: Joshua Название: Physiotherapy for Adult Neurological Conditions ISBN: 9811902089 ISBN-13(EAN): 9789811902086 Издательство: Springer Рейтинг: Цена: 16070.00 р. Наличие на складе: Поставка под заказ.
Описание: This is a comprehensive book on physiotherapy for adult neurological disorders with chapters describing physiotherapy assessment and management for those adult patients in the acute care and rehabilitation units of hospitals or centers.
Автор: Schreiber Название: Modern CNS Drug Discovery ISBN: 303062353X ISBN-13(EAN): 9783030623531 Издательство: Springer Рейтинг: Цена: 7685.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system.
Описание: This book focuses on a mathematical model describing a reduction in oxygen (O2) to the brain resulting from the impaired respiratory function of the lungs caused by COVID-19. The dynamics of blood flow along the brain capillaries and tissue are modeled as systems of ordinary and partial differential equations (ODE/PDEs).
Описание: Provides the most comprehensive coverage of the broad range of topics related to the neuroscience of aging Features sections on diagnosis and biomarkers of neurological aging, Alzheimers, and stroke Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Focuses on neurological diseases and conditions linked to aging, environmental factors, and clinical recommendations Includes more than 500 illustrations and tables
Автор: Lester Packer; Leonid Prilipko Название: Free Radicals in the Brain ISBN: 3642776116 ISBN-13(EAN): 9783642776113 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Free radicals appear to play a mojor role in many neurological (and non- neurological) dieseases. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 . . . . . . . . .
Название: Neurobiology of brain disorders ISBN: 0323856543 ISBN-13(EAN): 9780323856546 Издательство: Elsevier Science Рейтинг: Цена: 26107.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes quantum chaos and quantum transport in microscopic billiards. Microscopic billiards are typical dynamical systems in which it is easy to see chaos classically and also to investigate effects of chaos on quantum phenomena. Owing to recent progress in microstructure fabrication technology, quantum chaos can now be studied experimentally rather than only as a sophisticated theory.
Автор: Akash Название: Environmental Contaminants and Neurological Disorders ISBN: 3030663787 ISBN-13(EAN): 9783030663780 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume discusses how environmental pollutants are involved in the pathogenesis of neurological disorders, and covers specific mechanisms and risk factors, as well as the necessary strategies to reduce the adverse impacts of environmental pollutants on the human nervous system.
Автор: Tripathi Название: Gut Microbiome in Neurological Health and Disorders ISBN: 9811945292 ISBN-13(EAN): 9789811945298 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an overview of bidirectional communication between gut-microbiome-brain, pathways, nutrients, and metabolites that are involved in microbiota gut-brain axis (MGBA) interactions. Further it reviews the relevance of this axis in the neurological disorders and potential therapeutic interventions, involving gut microbiome or probiotics and prebiotics which can ameliorate the neurological disorders. The book examines the role of gut microbiota in the establishment and hemostasis of innate immune response and explores the possibility of development of microbiome-targeted therapeutic interventions. Notably, the book discusses the role of the gut microbiota and immune system on the maintenance of brain functions and the development of neurological disorders. It also highlights the recent advances in improving neurological diseases by phytochemicals, prebiotics and probiotics. This book is useful for researchers working in neuropharmacology, Clinical Research, toxicology, neurodegeneration, and stroke biology.
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