Synaptic Vesicles: Methods and Protocols, Dahlmanns Jana, Dahlmanns Marc
Автор: Michael R. Kreutz; Carlo Sala Название: Synaptic Plasticity ISBN: 3709117321 ISBN-13(EAN): 9783709117323 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book introduces current concepts of molecular mechanisms in synaptic plasticity, and offers a comprehensive overview of cutting-edge technology used to investigate the molecular dynamics of the synapses. Coverage includes clinical and applied aspects.
Автор: Helmut L. Haas; E. Grastyan; Gy?rgy Buzsaki Название: Synaptic Plasticity in the Hippocampus ISBN: 3642732046 ISBN-13(EAN): 9783642732041 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is the second time that I have had the honor of opening an interna- tional symposium dedicated to the functions of the hippocampus here in Pecs. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip- pocampal phenomena at the most elementary level.
Автор: Melanie A. Woodin; Arianna Maffei Название: Inhibitory Synaptic Plasticity ISBN: 1489981276 ISBN-13(EAN): 9781489981271 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume will explore the most recent findings on cellular mechanisms of inhibitory plasticity and its functional role in shaping neuronal circuits, their rewiring in response to experience, drug addiction and in neuropathology. Inhibitory Synaptic Plasticity will be of particular interest to neuroscientists and neurophysiologists.
Автор: Dennis J. Selkoe; Antoine Triller Название: Synaptic Plasticity and the Mechanism of Alzheimer`s Disease ISBN: 3642095194 ISBN-13(EAN): 9783642095191 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A biochemical hypothesis - that Alzheimer`s disease (AD) is a progressive cerebral amyloidosis caused by the aggregation of the amyloid b-protein (Ab) - preceded and enabled the discovery of etiologies.
Автор: Maxwell Bennett; Jim Lagopoulos Название: Stress, Trauma and Synaptic Plasticity ISBN: 3319911155 ISBN-13(EAN): 9783319911151 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents the latest state of knowledge on grey matter changes in the brain following stress and trauma. Where do these changes take place and what are the underlying molecular mechanisms? These questions are addressed in several sections, providing detailed insights into the cellular and molecular alterations that occur in the brain after stress and trauma.The changes to the grey matter in certain areas of the brain are similar in stressed humans and animals, with the most likely basis for these changes being the degeneration of synaptic connections. In the book’s first sections the reader will learn about the core network of synaptic connections that are affected by stress and trauma disorders. These synaptic connections are modulated by dopamine, serotonin and Brain Derived Neurotrophic Factor (BDNF). In subsequent chapters, the NMDA-receptor mediated plasticity of these synapses is discussed, with particular attention given to how glucocorticoids can interfere with the function of BDNF and thereby affect the synapse’s physical stability. Furthermore, the reader will learn about the importance of the genetics of the glucocorticoid gene and the epigenetic control of BDNF in connection with synaptic plasticity. The authors conclude by integrating the observations summarized in the previous sections so as to present plausible hypotheses regarding the identity of the networks, synapses and molecular pathways that support fear and extinction. Providing an up-to-date overview of the mechanisms of synaptic plasticity and physiological changes in the stressed and traumatized brain, this book will appeal to researchers, clinicians and students in the neurosciences. M. R. Bennett AO is an internationally renowned neuroscientist. He is a professor of Neuroscience & University Chair at the University of Sydney, the founding director of the ‘Brain and Mind Research Institute’ and has been the president and organizer of many societies and symposia. His research has led to groundbreaking revelations in understanding synaptic functioning. He is the author of numerous papers and books, including ‘Philosophical Foundations of Neuroscience’ (2003 with Peter Hacker) and the recent works ‘Virginia Woolf and Neuropsychiatry’ (2013), ‘History of Cognitive Neuroscience (2008 with Peter Hacker) and ‘Neuroscience and Philosophy: Brain, Mind and Language (2006 with Daniel Dennett, John Searle and Peter Hacker). Prof. Bennett has received the leading award in biology and medicine in Australia (the Macfarlane Burnet Medal) as well as being made an ‘Office of the Order of Australia’ for his outstanding ‘service to the biological sciences, particularly in the field of neurosciences’. Professor J. Lagopoulos is the inaugural director of the Sunshine Coast Mind and Neuroscience – Thompson Institute, which focuses on mental health and neurological research, clinical services and teaching. He is an expert in magnetic resonance imaging (MRI) and has been involved in neuroimaging for over 20 years. His work focuses on youth mental health, post-traumatic stress disorders, traumatic brain injury and healthy brain ageing and dementia. Prof. Lagopoulos is a leading academic and medical specialist who has published more than 170 peer-reviewed papers and contributed to several books. He is member of numerous international societies, including the ‘International Society for Magnetic Resonance in Medicine’ and the ‘Organization of Human Brain Mapping’. He has received several awards, including the ‘Westmead Foundation Prize’.
Автор: Herbert Zimmermann Название: Cellular and Molecular Basis of Synaptic Transmission ISBN: 3642731740 ISBN-13(EAN): 9783642731747 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Cellu- lar and Molecular Basis of Neuronal Signalling Held in Gottingen, FRG, September 9-13, 1987
Автор: R. Tapia Название: Regulatory Mechanisms of Synaptic Transmission ISBN: 1468439707 ISBN-13(EAN): 9781468439700 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book, which originated in the presentations of a symposium sponsored by the Universidad Nacional Autonoma de Mexico, held in Mexico City on April 14-16, 1980, represents an attempt to analyze some of the most relevant aspects of synaptic transmission.
Автор: K. Kuba; H. Higashida; D.A. Brown; T. Yoshioka Название: Slow Synaptic Responses and Modulation ISBN: 4431669752 ISBN-13(EAN): 9784431669753 Издательство: Springer Рейтинг: Цена: 9083.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Information flow as nerve impulses in neuronal circuits is regulated at synapses. The synapse is therefore a key element for information processing in the brain. Much attention has been given to fast synaptic transmission, which predominantly regulates impulse-to-impulse transmission. Slow synaptic transmission and modu- lation, however, sometimes have been neglected in considering and attempting to understand brain function. Slow synaptic potentials and modulation occur with a considerable delay in response to the accumulation of synaptic and modulatory inputs. In these contexts, they are plastic in nature and play important roles in information processing in the brain. A symposium titled "Slow Synaptic Responses and Modulation" was held as the satellite symposium to the 75th Annual Meeting of the Physiological Society of Japan on March 30-31, 1998, in Kanazawa. The theme was selected not only for the reason mentioned above, but also because of the considerable involvement of many Japanese scholars in establishing the basic issues. Following the dawn of synaptic physiological research, as Sir John Eccles, Sir Bernard Katz, and Professor Stephen Kuffler carried out pioneer work, Professor Kyozou Koketsu and Professor Benjamin Libet, the students of Sir John Eccles, and their colleagues established the concept of slow synaptic responses and modulation by studying vertebrate sympathetic ganglia. Since then, the concept has been ex- panded with detailed investigations of both peripheral and central synapses at the levels of single ion channels, intracellular Ca"] dynamics, intracellular transduc- tion mechanisms, and genes.
Автор: Nicholas Graziane; Yan Dong Название: Electrophysiological Analysis of Synaptic Transmission ISBN: 1493980092 ISBN-13(EAN): 9781493980093 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Electrophysiological methods are used at nearly all levels of biological research today. Dr. Yan Dong, an expert in utilizing electrophysiological techniques for brain research with fifteen years of experience, and Peter Neumann hope this work can act as a concise and practical aid to remedy the current situation.
Автор: Sushil K. Jha; Vibha M. Jha Название: Sleep, Memory and Synaptic Plasticity ISBN: 9811328137 ISBN-13(EAN): 9789811328138 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Over the years there has been growing interest among the scientific community in investigating sleep and how it affects the memory and other brain functions. It is now well established that sleep helps in memory consolidation and induction of neural plasticity, and that short-term deprivation of either total sleep or rapid eye movement sleep alone can induce memory deficits very quickly. Quantitative and qualitative changes in sleep architecture after different training tasks further suggest that discrete memory types may require specific sleep stage/s for optimal memory consolidation, and studies indicate that sleep deprivation alters synaptic plasticity and membrane excitability in the hippocampal neurons and synaptic up-scaling in the cortical neurons. Further, sleep alteration during pregnancy may increase the risk of depression and adversely affect maternal-child relationships, parenting practices, family functioning, and children's development and general wellbeing.
This book coherently discusses all these aspects, with a particular focus on the possible role of sleep in memory consolidation and synaptic plasticity. It also highlights the detrimental effects of sleep loss on mental health, the immune system and cognition.
This book is a valuable reference resource for students and researchers working in the area of sleep, memory, or neuronal plasticity.
Автор: Peter V. Nguyen Название: Multidisciplinary Tools for Investigating Synaptic Plasticity ISBN: 1493959190 ISBN-13(EAN): 9781493959198 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights methods for probing the cellular and molecular mechanisms of synaptic plasticity in the nervous systems of vertebrate and invertebrate species. Includes strategies for studying plasticity, neural development and synaptogenesis and more.
1. The Brain on Stress: The Good and the Bad Bruce S. McEwen
2. Regulation of Excitatory Synapses by Stress Hormones Marian Joлls, Harm Krugers, Henk Karst
3. Synaptic Stress, Changes in Glutamate Transmission and Circuitry, and Psychopatology Laura Musazzi, Giulia Treccani, Carla Perego, Nicoletta Nava, Jens R Nyengaard, Maurizio Popoli
4. Dual Regulation of Glutamatergic Transmission and Cognition by Stress in Prefrontal Cortex Zhen Yan
5. Role of Endocannabinoids in Regulating Glucocorticoid Effects on Memory for Emotionally Arousing Experiences Piray Atsak, Benno Roozendaal, Patrizia Campolongo
6. Endocannabinoid Signaling & Synaptic Plasticity During Stress J. Megan Gray, Haley A. Vecchiarelli, Matthew N. Hill
7. Stress Induced Metaplasticity at GABA Synapses Jaideep S. Bains
8. Stress Modulation of Synaptic Plasticity in the Hippocampus Menahem Segal, Nicola Maggio
9. Neural-Cognitive Effects of Stress in the Hippocampus Jeansok J. Kim, Blake A. Pellman, Eun Joo Kim
10. Evolutionary, Historical and Mechanistic Perspectives on How Stress Affects Memory and Hippocampal Synaptic Plasticity George E. Farmer, Collin R. Park, Laura A. Bullard, David M. Diamond
11. Acute Stress Disrupts Short- and Long-term Patterns of Synaptic Plasticity in Dorsal Hippocampus and Subiculum: Implications for Hippocampal Output and Behaviour John G. Howland, Don A. Davies
12. Synaptic Mechanisms and Cognitive Computations Underlying Stress Effects on Cognitive Function Gediminas Luksys, Carmen Sandi
13. Altered GABA Function in Major Depression Beverly French, Marianne L. Seney, Etienne Sibille
14. Pathology in Astroglia, Glutamate and GABA in Major Depressive Disorder: Evidence from Studies of Human Postmortem Tissue Grazyna Rajkowska
15. Evidence of Glutamatergic Dysfunction in the Pathophysiology of SchizophreniaJ.C. Hammond, D. Shan, J.H. Meador-Woodruff, R.E. McCullumsmith
16. Metabolic Stress and Neuropsychiatric Disorders Claudia A. Grillo, Lawrence P. Reagan
17. Using our Understanding of Stress Related Effects on Glutamate Neurotransmission to Guide the Development of Novel Treatment Strategies Carly Kiselycznyk, Gerard Sanacora
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