Optimization of Pharmaceutical Processes, Fytopoulos Antonios, Ramachandran Rohit, Pardalos Panos M.
Автор: Watson David G. Название: Pharmaceutical Analysis. 5 ed ISBN: 0702078077 ISBN-13(EAN): 9780702078071 Издательство: Elsevier Science Рейтинг: Цена: 5305.00 р. 7578.00-30% Наличие на складе: Есть (5 шт.) Описание: Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. The mathematics involved is notoriously difficult, but this much-praised textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Two new chapters have been added to the new edition covering methods used in the quality control of biotechnologically produced drugs, and electrochemical biosensors. There is continuous learning reinforcement throughout the book by way of worked calculation examples and self-assessment test questions. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes Two new chapters: Chapter 16 Methods used in the quality control of biotechnologically produced drugs Chapter 17 Electrochemical biosensors
The definitive textbook on the chemical analysis of pharmaceutical drugs - fully revised and updated
Introduction to Pharmaceutical Analytical Chemistry enables students to gain fundamental knowledge of the vital concepts, techniques and applications of the chemical analysis of pharmaceutical ingredients, final pharmaceutical products and drug substances in biological fluids. A unique emphasis on pharmaceutical laboratory practices, such as sample preparation and separation techniques, provides an efficient and practical educational framework for undergraduate studies in areas such as pharmaceutical sciences, analytical chemistry and forensic analysis. Suitable for foundational courses, this essential undergraduate text introduces the common analytical methods used in quantitative and qualitative chemical analysis of pharmaceuticals.
This extensively revised second edition includes a new chapter on chemical analysis of biopharmaceuticals, which includes discussions on identification, purity testing and assay of peptide and protein-based formulations. Also new to this edition are improved colour illustrations and tables, a streamlined chapter structure and text revised for increased clarity and comprehension.
Introduces the fundamental concepts of pharmaceutical analytical chemistry and statistics
Presents a systematic investigation of pharmaceutical applications absent from other textbooks on the subject
Examines various analytical techniques commonly used in pharmaceutical laboratories
Provides practice problems, up-to-date practical examples and detailed illustrations
Includes updated content aligned with the current European and United States Pharmacopeia regulations and guidelines
Covering the analytical techniques and concepts necessary for pharmaceutical analytical chemistry, Introduction to Pharmaceutical Analytical Chemistry is ideally suited for students of chemical and pharmaceutical sciences as well as analytical chemists transitioning into the field of pharmaceutical analytical chemistry.
Описание: Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target.
Описание: Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals.
The mathematics involved is notoriously difficult, but this much-praised textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Two new chapters have been added to the new edition covering methods used in the quality control of biotechnologically produced drugs, and electrochemical biosensors. There is continuous learning reinforcement throughout the book by way of worked calculation examples and self-assessment test questions.
Stochastic global optimization methods and applications to chemical, biochemical, pharmaceutical and environmental processes presents various algorithms that include the genetic algorithm, simulated annealing, differential evolution, ant colony optimization, tabu search, particle swarm optimization, artificial bee colony optimization, and cuckoo search algorithm. The design and analysis of these algorithms is studied by applying them to solve various base case and complex optimization problems concerning chemical, biochemical, pharmaceutical, and environmental engineering processes.
Design and implementation of various classical and advanced optimization strategies to solve a wide variety of optimization problems makes this book beneficial to graduate students, researchers, and practicing engineers working in multiple domains. This book mainly focuses on stochastic, evolutionary, and artificial intelligence optimization algorithms with a special emphasis on their design, analysis, and implementation to solve complex optimization problems and includes a number of real applications concerning chemical, biochemical, pharmaceutical, and environmental engineering processes.
Автор: Zoran Antonijevic Название: Optimization of Pharmaceutical R&D Programs and Portfolios ISBN: 3319090747 ISBN-13(EAN): 9783319090740 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Some development strategies that are discussed are indication sequencing, optimal number of programs and optimal decision criteria.This book includes chapters written by authors with very broad backgrounds including financial, clinical, statistical, decision sciences, commercial and regulatory.
Описание: This volume presents and discusses the vital precepts underlying the efficient, effective, and cost-effective development of pharmaceutical drug products. It focuses on the adoption of systematic quality principles of pharmaceutical development.
Описание: This book provides a complete guide on tools and techniques for modeling of supercritical and subcritical fluid extraction (SSFE) processes and phenomena. It provides details for SSFE from managing the experiments to modeling and optimization. It includes the fundamentals of SSFE as well as the necessary experimental techniques to validate the models. The optimization section includes the use of process simulators, conventional optimization techniques and state-of-the-art genetic algorithm methods. Numerous practical examples and case studies on the application of the modeling and optimization techniques on the SSFE processes are also provided. Detailed thermodynamic modeling with and without co-solvent and non equilibrium system modeling is another feature of the book.
The book consists of seven chapters. Chapter 1 presents an overview of the field of supercritical and subcritical fluid extraction (SSFE) and their importance to food, cosmetic and pharmaceutical industries. Chapter 2 describes the concepts and methodologies for modeling, simulation as well as optimization. It presents conservation laws related to SFE traditional first principle modeling and optimization techniques, statistical modeling as well as advanced artificial intelligence (AI) techniques like genetic algorithm, fuzzy logic and artificial neural network (ANN). The characteristics and physical properties of palm oil as the most referred solute in the book, and descriptions of some existing palm oil industrial processes are presented in Chapter 3. In Chapter 4, the first principle methodology is applied for modeling of properties of palm oil components, mixtures and for the supercritical fluid extraction of palm oil components. Modeling applications involving advanced techniques such as AI, ANN and fuzzy logics and ANFIS are discussed in Chapter 5. Next, Chapter 6 describes experimental design concepts and procedures as well as statistical optimization techniques involving SSFE processes. Finally, optimisation of SSFE using first principle modeling and other advanced techniques are presented in Chapter 7.
Описание: This book discusses the intelligent optimization and control of complex metallurgical processes, including intelligent optimization and control of raw-material proportioning processes, coking process, and reheating furnaces;
Автор: Christianto Wibowo, Ka Ming Ng Название: Conceptual Design of Crystallization Processes ISBN: 1501519875 ISBN-13(EAN): 9781501519871 Издательство: Walter de Gruyter Рейтинг: Цена: 14495.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The book presents, in a unified manner, various crystallization design methods. It discusses in detail the geometric framework for representing complex phase behavior involving multiple solutes, enantiomers, hydrates, compounds, polymorphs, and solid solutions through visualization of high-dimensional phase diagrams. It also describes how the impact of transport processes is accounted for using kinetically controlled process paths.
Nuclear Energy: An Introduction to the Concepts, Systems, and Applications of Nuclear Processes, Eighth Edition, provides essential information on basic nuclear physics, systems and the applications of nuclear energy. It comprehensively covers Basic Concepts, Radiation and Its Uses, and Nuclear Power, providing students with a broad view of nuclear energy and science in a fast-paced format that features updated, timely content on topics of new and growing importance to current and future nuclear professionals, such as tritium-powered betavoltaic integrated circuit chips, the modulation of radioactive decay constant due to solar activity, Monte Carlo radiation transport calculations and accelerator-driven systems.
This book is an essential resource for any first course on nuclear energy and systems.
Contains coverage of timely topics, such as the connection between hydraulic fracturing (fracking), radioactivity and nuclear forensics
Covers the TerraPower traveling wave reactor, the first ever FDA approved drug for the treatment of acute radiation injury, and more
Describes the industry response to the Fukushima nuclear disaster, including FLEX in the U.S.
Includes more worked examples and end of chapter exercises
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