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Glutamate and Neuropsychiatric Disorders: Current and Emerging Treatments, Pavlovic Zoran M.


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Автор: Pavlovic Zoran M.
Название:  Glutamate and Neuropsychiatric Disorders: Current and Emerging Treatments
ISBN: 9783030874797
Издательство: Springer
Классификация:




ISBN-10: 3030874796
Обложка/Формат: Hardcover
Страницы: 638
Вес: 1.06 кг.
Дата издания: 11.04.2022
Язык: English
Издание: 1st ed. 2022
Иллюстрации: 35 tables, color; 40 illustrations, color; 3 illustrations, black and white; xxxv, 600 p. 43 illus., 40 illus. in color.
Размер: 23.39 x 15.60 x 3.51 cm
Читательская аудитория: Professional & vocational
Подзаголовок: Current and emerging treatments
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Disorder, Bipolar Disorder, Autism Spectrum Disorders (ASD), Posttraumatic Stress Disorder (PTSD), Alzheimer’s Dementia, Schizophrenia, Impulsive Aggression, Substance Use Disorders (SUD), Amyotrophic Lateral Sclerosis (ALS), Chronic Pain, Multiple Sclerosis, Parkinson’s Disease, Attention Deficit Hyperactivity Disorder (ADHD), Migraine, Epilepsy and Anxiety disorders. Moreover, the book includes an extensive overview of glutamatergic treatments already available on the market, and those which are currently in pharmaceutical drug development pipelines. The primary beneficiaries will be neurology and psychiatry specialists and residents, neuroscientists, neuropharmacologists, pharmaceutical industry and clinical research organization professionals, academics, and clinicians working with psychiatric and neurological patients with comorbidities such as cardiologists, pulmonologists, and endocrinologists. This book will also appeal to psychiatry and neurology subspecialists and clinicians working in neuroscience labs seeking an easy-to-understand yet comprehensive overview of contemporary evidence-based clinical insights backed by basic science (preclinical) research evidence. Given its scope, the book is also a unique and indispensable resource for both preclinical and clinical neuroscientists, medical advisors, and clinical research specialists in the pharmaceutical industry. In addition, it will appeal to neuroscience and neuropsychopharmacology students and guide them through the complexities of glutamate involvement in the pathophysiology of the most common debilitating brain diseases with high unmet medical needs.
Дополнительное описание: Treatments Against Glutamatergic Excitotoxicity in Ischemic Stroke.- Definitions and Concepts of Stress.- Role of Glutamatergic Neurotransmission in the Pathophysiology of Stress-Related Disorders and Chronic Stress Response.- Current Glutamatergic Treatm



Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders

Автор: Weizman
Название: Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders
ISBN: 9048177383 ISBN-13(EAN): 9789048177387
Издательство: Springer
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Цена: 40389.00 р.
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Описание: This book provides an up-to-date overview of the role of neurosteroids and neuroactive steroids in the regulation of brain processes and neuropsychiatric disorders. It addresses the neurosteroid function in brain development and plasticity, in both the normal and the pathological brain.

Transcranial Direct Current Stimulation in Neuropsychiatric Disorders: Clinical Principles and Management

Автор: Brunoni Andrй, Nitsche Michael A., Loo Colleen
Название: Transcranial Direct Current Stimulation in Neuropsychiatric Disorders: Clinical Principles and Management
ISBN: 3030761355 ISBN-13(EAN): 9783030761356
Издательство: Springer
Цена: 30745.00 р.
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Описание: The 2nd edition of this book incorporates the tremendous clinical advances that have occurred in the field of transcranial direct current stimulation (tDCS) over the past 5 years.

Transcranial Direct Current Stimulation in Neuropsychiatric Disorders

Автор: Andr? Brunoni; Michael Nitsche; Colleen Loo
Название: Transcranial Direct Current Stimulation in Neuropsychiatric Disorders
ISBN: 331981642X ISBN-13(EAN): 9783319816425
Издательство: Springer
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Цена: 13974.00 р.
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Описание: The aim of this book is to provide a comprehensive review of the use of Transcranial Direct Current Stimulation (tDCS) in different psychiatric conditions. Here we review tDCS clinical studies employing different types of design (from single-session tDCS studies to randomized clinical trials) as well as studies evaluating the impact of tDCS in neurophysiological, behavioral and brain imaging outcomes.Although the understanding about physiological foundations and effectiveness of clinical therapies of psychiatric diseases has been considerably increased during the last decades, our knowledge is still limited, and consequently psychiatric diseases are still a major burden to the individual patient and society. Recently, interest in pathological alterations of neuroplasticity in psychiatric diseases as a critical condition for development, and amelioration of clinical symptoms increased, caused by the fact that new tools, such as functional imaging, and brain stimulation techniques do allow to monitor, and modulate these phenomena in humans. Especially non-invasive brain stimulation techniques evolved as an attractive potential new therapeutic tool. The interest in non-invasive brain stimulation has grown exponentially in the past 25 years, with the development of non-pharmacological, neuromodulatory techniques such as tDCS and repetitive transcranial magnetic stimulation (rTMS). TDCS, although even newer than rTMS, has attracted considerable attention in both basic and clinical research scenarios. In the context of clinical research, tDCS is being increasingly investigated as a novel treatment tool for several psychiatric disorders, such as major depression, schizophrenia and neurocognitive and substance abuse disorders.Transcranial Direct Current Stimulation in Neuropsychiatric Disorders – Clinical Principles and Management intends to serve as a practical guide on the field, attracting the interest of psychiatrists, neurologists and neuroscientists with little or no experience with tDCS, as well as those with a background on tDCS who want to increase their knowledge in any particular psychiatric condition.

Staging Neuropsychiatric Disorders

Автор: Tom?s Palomo; Richard M. Kostrzewa; Richard J. Ben
Название: Staging Neuropsychiatric Disorders
ISBN: 1489986847 ISBN-13(EAN): 9781489986849
Издательство: Springer
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Цена: 22359.00 р.
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Описание: Book chapters are authored by participants in the International Meeting on Staging Neuropsychiatric Disorders: Implications for Etiopathogenesis and Treatment, held in Moj?car (Almer?a) Spain from 14-18 October 2009. Chapters are organized into four sections on themes encompassed by Staging Neuropsychiatric Disorders: Clinical Staging in the Pathophysiology of Psychotic and Affective Disorders, Staging Perspectives in Neurodevelopmental Aspects of Neuropsychiatry, Epigenetics and Biomarkers in the Staging of Neuropsychiatric Disorders, and Staging Neurodegenerative Disorders. This volume should serve as a resource for physicians and neuroscientists alike, highlighting the importance of staging neuropsychiatric disorders and the underlying mechanistic dysfunction, for prevention and treatment strategies at different stages of disease progression. Earlier volumes in the series, published by the Fundaci?n Cerebro y Mente in Madrid, Spain: Depressive, Anxiety and Drug Abuse Disorders Eds: T. Palomo and T. Archer Schizophrenia, Movement Disorders and Age Related Cognitive Disorders Eds.: T. Palomo, T. Archer and R.J. Beninger Dopamine Disease States Eds.: R.J. Beninger, T. Palomo and T. Archer Interactive Monoaminergic Disorders Eds.: T. Palomo, R.J. Beninger and T. Archer Neurodegenerative Brain Disorders Eds.: T. Palomo, R.J. Beninger and T. Archer Neurodevelopmental Liabilities in Brain Disease States Eds.: R.J. Beninger, T. Palomo, R.M. Kostrzewa and T. Archer Gene-Environment Interplay in Brain Disease States Eds.: T. Palomo, R.J. Beninger, R.M. Kostrzewa and T. Archer Implications of CoMorbidity for Etiology and Treatment of Neuropsychiatric Disorders Eds.: T. Palomo, R.J. Beninger, R.M. Kostrzewa and T. Archer Beyond Neuropsychiatric Diagnostics: Symptoms not Disorders Eds.: T. Palomo, R.J. Beninger, R.M. Kostrzewa and T. Archer

Transgenic and Knockout Models of Neuropsychiatric Disorders

Автор: Gene S. Fisch; Jonathan Flint
Название: Transgenic and Knockout Models of Neuropsychiatric Disorders
ISBN: 1617376078 ISBN-13(EAN): 9781617376078
Издательство: Springer
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Цена: 34799.00 р.
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Описание: In this up-to-date survey and critical assessment of transgenic and knockout models in neuropsychiatry and behavior, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond.

Staging Neuropsychiatric Disorders

Автор: Tom?s Palomo; Richard M. Kostrzewa; Richard J. Ben
Название: Staging Neuropsychiatric Disorders
ISBN: 148999646X ISBN-13(EAN): 9781489996466
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This book features chapters by participants of the International Meeting on Staging Neuropsychiatric Disorders: Implications for Etiopathogenesis and Treatment. It highlights prevention and treatment strategies at different stages of disease progression.

Neuroactive Steroids in Brain Function , Behavior and Neuropsychiatric Disorders

Автор: Ristner
Название: Neuroactive Steroids in Brain Function , Behavior and Neuropsychiatric Disorders
ISBN: 1402068530 ISBN-13(EAN): 9781402068539
Издательство: Springer
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Цена: 40389.00 р.
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Описание: Offers a comprehensive overview of the role of neurosteroids and neuroactive steroids, such as pregnenolone and dehydroepiandrosterone, allopregnanolone, progesterone and others in the regulation of brain processes and neuropsychiatric disorders.

Cannabinoids and Neuropsychiatric Disorders

Автор: Murillo-Rodriguez Eric, Pandi-Perumal S. R., Monti Jaime M.
Название: Cannabinoids and Neuropsychiatric Disorders
ISBN: 3030573680 ISBN-13(EAN): 9783030573683
Издательство: Springer
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: ​ - Constituents of Cannabis Sativa. - Neuromolecular Mechanisms of Cannabis Action. - Neuropharmacological Effects of the Main Phytocannabinoids: A Narrative Review. - Emerging Roles of Cannabinoids and Synthetic Cannabinoids in Clinical Experimental Models. - Cannabis and Depression. - Recent Advances in the Potential of Cannabinoids for Neuroprotection in Alzheimer's, Parkinson's, and Huntington's Diseases. - Cannabidiol Therapy for Refractory Epilepsy and Seizure Disorders. - Cannabinoid-Based Medicines and Multiple Sclerosis. - Psychiatric Disorders and Cannabinoid Receptors.

Neuropsychiatric Symptoms of Movement Disorders

Автор: Heinz Reichmann
Название: Neuropsychiatric Symptoms of Movement Disorders
ISBN: 3319351761 ISBN-13(EAN): 9783319351766
Издательство: Springer
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Цена: 16769.00 р.
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Описание:

Depression, Apathy, Anhedonia, Fatigue in Parkinson's Disease.- Mild Cognitive Impairment in Parkinson's Disease.- Parkinson's Disease Dementia.- Impulse Control Disorders.- Influence of Dietary Constituents on Motor and Non-Motor Symptoms in Parkinson's Disease.- Psychosis in Parkinson's Disease.- Neuropsychiatric Manifestations in Atypical Parkinsonian Syndromes.- Neuropsychiatric Disturbances in Dystonia.- Depression in Huntington's Disease.- Cognitive Impairment and Dementia (Mild or Major Neurocognitive Disorder) in Huntington's Disease.- Tics.- Wilson's Disease.- Ataxia.

Neuropsychiatric Disorders and Epigenetics

Автор: Yasui, Dag
Название: Neuropsychiatric Disorders and Epigenetics
ISBN: 0128002263 ISBN-13(EAN): 9780128002261
Издательство: Elsevier Science
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Цена: 13980.00 р.
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Описание:

Neuropsychiatric Disorders and Epigenetics is a comprehensive reference for the epigenetic basis of most common neuropsychiatric disorders. The volume is organized into chapters representing individual neuropsychiatric disorders, from addition to obesity contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects of environmental stimuli on epigenetic states is particularly relevant o disease.

Recent discoveries in epigenetic research enabled by epic advances in genomic technologies have positioned the field for broad translation to therapeutic interventions for previously unmanageable disorders Neuropsychiatric disorders represent a prime target of epigenetic interventions as they are highly debilitating, often chronic diseases with enormous costs to society. Thus, this volume will help define epigenetics as a key player in neuropsychiatric disorders, highlighting the full spectrum of epigenetic mechanisms underlying such disorders and introducing the vast range of epigenetic therapies under development.

  • Analyzes the effects of environmental stimuli on epigenetic states that correlate with neuropsychiatric disease induction
  • Reviews the epigenetic basis for common neuropsychiatric disorders, thereby guiding translational therapies for clinicians and mechanistic studies for scientists
  • Extensive use of diagrams, illustrations, tables, and graphical abstracts for each section providing rapid assessment

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