Автор: D. Celentano, M. Szklo Название: Gordis Epidemiology - 6th ed. ISBN: 0323552293 ISBN-13(EAN): 9780323552295 Издательство: Elsevier Science Рейтинг: Цена: 7073.00 р. Наличие на складе: Поставка под заказ.
Описание:
From the Department of Epidemiology at Johns Hopkins University and continuing in the tradition of award-winning educator and epidemiologist Dr. Leon Gordis, comes the fully revised 6th Edition of Gordis Epidemiology. This bestselling text provides a solid introduction to basic epidemiologic principles as well as practical applications in public health and clinical practice, highlighted by real-world examples throughout. New coverage includes expanded information on genetic epidemiology, epidemiology and public policy, and ethical and professional issues in epidemiology, providing a strong basis for understanding the role and importance of epidemiology in today's data-driven society.
Covers the basic principles and concepts of epidemiology in a clear, uniquely memorable way, using a wealth of full-color figures, graphs, charts, and cartoons to help you understand and retain key information.
Reflects how epidemiology is practiced today, with a new chapter organization progressing from observation and developing hypotheses to data collection and analyses.
Features new end-of-chapter questions for quick self-assessment, and a glossary of genetic terminology.
Provides more than 200 additional multiple-choice epidemiology self-assessment questions online.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Описание: Cellular-molecular approach to evolution has led to radical changes in our understanding of biologic principles ranging from the Cell, to the Life Cycle, Development, Homeostasis, Senescence/Aging, Heterochrony, Pleiotropy, Phenotype, and perhaps the purpose of life itself. Much of this new way of thinking about biology and medicine emanates from experimental evidence for epigenetic inheritance. This leads one to question whether our unicellular state is the actual primary level of selection. One particular system that is now recognized as being under the auspices of epigenetic inheritance is the endocrine system, which is conventionally thought to regulate physiologic homeostasis. However, because the sex hormones play such a major role in behaviors related to the acquisition of epigenetic data, and the processing of such epigenetic data by the gonads during meiosis, their role in the evolution of the organism become tractable. The composite of the activities of the individual over the course of its lifetime can now be understood causally, resulting from the orchestration of its physiology by hormones, prenatally, postnatally and during the aging process, across the entire life span of the organism. Specific behaviors over the course of the life cycle during childhood, adolescence, puberty, adulthood and aging can now be understood mechanistically rather than merely as milestones in the various stages of life. With the above considerations in mind, this book presents the cellular-evolutionary perspective towards the relationship of the organism with its surroundings, human and non-human alike renders biology and medicine a continuum instead of fragmented, un-related anecdotes.
Chapter 2. Darwin, the Modern Synthesis, and a New Biology
Chapter 3. Cognition and the living condition
Chapter 4. What is consciousness? An Evolutionary Perspective
Chapter 5. Networking from the Cell to Quantum Mechanics as Consciousness
Chapter 6. The Nature of information and its communication
Chapter 7. The information cycle and biological information management
Chapter 8. Communication and the accumulation of genetic information
Chapter 9. Non-genic means of information reception and exchange
Chapter 10. The primacy of the unicellular state
Chapter 11. Phenotype, niche construction and natural cellular engineering
Chapter 12. Holobionts
Chapter 13. Four Domains: Cognition-based evolution
Chapter 14. Reconciling physics and biology
Chapter 15. What does this mean for evolution?
Chapter 16. Conclusion: Cellular-molecular evolution in the 21st century
Автор: Alexander Meissner; J?rn Walter Название: Epigenetic Mechanisms in Cellular Reprogramming ISBN: 3662510626 ISBN-13(EAN): 9783662510629 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offering an overview of current topics and concepts concerning mechanisms and consequences of epigenetic reprogramming, this book addresses biomedical researchers in search of more detailed knowledge of novel mechanisms and methods of study.
Описание: Section I: The physiology of the gene/environment interaction.- Nutrition.- Physical Exercise.- Circadian Rhythm.- Toxicants: Smoke, Alcohol and Heavy Metals.- Hormones.- Section II: Gene-Environment Interaction and Disease Susceptibility.- Obesity and Metabolic Syndromes.- Cancer.- Neurological and Psychiatric Disorders.- Asthma and allergic disorders.- Lamarck Versus Darwin: The Concept of Aquired Epigenetic Inheritance.- Section III: Genome/Epigenome.- Genetic Contribution to Epigenetic Inheritance.- The Controversial Role of DNA Methylation in Epigenetic Inheritance.- Small Non-Coding RNAs.- Chromatin Modifiers.- Soma-to-Germline Information Transfer: Questions and Promises.
Описание: Human trafficking is one of the most pressing social justice issues of our time. Though renewed interest in this issue among Christians is a wonderful thing, misinformed and misguided efforts can do more harm than good. Written by seasoned leaders and grounded in theology and up-to-date data, this accessible and compelling handbook will educate churches and organizations for truly effective work.
Автор: Vladimir A. Botchkarev; Sarah E. Millar Название: Epigenetic Regulation of Skin Development and Regeneration ISBN: 3030132374 ISBN-13(EAN): 9783030132378 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Поставка под заказ.
Описание: This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists.
Автор: Squier Susan Merrill Название: Epigenetic Landscapes: Drawings as Metaphor ISBN: 0822368722 ISBN-13(EAN): 9780822368724 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 4383.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Devised in the 1940s by the biologist C. H. Waddington, the epigenetic landscape is a metaphor for how gene regulation modulates cellular development. As a scientific model, it fell out of use in the late 1960s but returned at the beginning of the twenty-first century with the advent of big-data genomic research because of its utility among scientists across the life sciences to think more creatively about and to discuss genetics. In Epigenetic Landscapes Susan Merrill Squier follows the model’s cultural trail, from its first visualization by the artist John Piper to its use beyond science. Squier examines three cases in which the metaphor has been imaginatively deployed to illustrate complex systems that link scientific and cultural practices: graphic medicine, landscape architecture, and bioArt. Challenging reductive understandings of epigenetics, Squier boldly reclaims the broader significance of the epigenetic landscape as a figure at the nexus of art, design, and science.
Автор: Susan Merrill Squier Название: Epigenetic Landscapes: Drawings as Metaphor ISBN: 0822368609 ISBN-13(EAN): 9780822368601 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 17550.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Devised in the 1940s by the biologist C. H. Waddington, the epigenetic landscape is a metaphor for how gene regulation modulates cellular development. As a scientific model, it fell out of use in the late 1960s but returned at the beginning of the twenty-first century with the advent of big-data genomic research because of its utility among scientists across the life sciences to think more creatively about and to discuss genetics. In Epigenetic Landscapes Susan Merrill Squier follows the model’s cultural trail, from its first visualization by the artist John Piper to its use beyond science. Squier examines three cases in which the metaphor has been imaginatively deployed to illustrate complex systems that link scientific and cultural practices: graphic medicine, landscape architecture, and bioArt. Challenging reductive understandings of epigenetics, Squier boldly reclaims the broader significance of the epigenetic landscape as a figure at the nexus of art, design, and science.
Автор: Cabej, Nelson R. (department Of Biology, Universit Название: Epigenetic mechanisms of the cambrian explosion ISBN: 0128143118 ISBN-13(EAN): 9780128143117 Издательство: Elsevier Science Рейтинг: Цена: 11957.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Epigenetic Mechanisms of the Cambrian Explosion provides readers with a basic biological knowledge and epigenetic explanation of the biological puzzle of the Cambrian explosion, the unprecedented rapid diversification of animals that began 542 million years ago. During an evolutionarily instant of 10 million years, which represents only 0.3% of the time of existence of life on Earth, or less than 2% of the time of existence of metazoans, all of the 30 extant body plans, major animal groups (phyla) and several extinct groups appeared. The work helps address this phenomena and tries to answer remaining questions for evolutionary biology, epigenetics, and scientific researchers.
The book recognizes and presents objective representations of alternative theories for epigenetic evolution in this period, with the author drawing on his epigenetic theory of evolution to explain the causal basis of the Cambrian explosion. Both empirical evidence and theoretical arguments are presented in support of this thought-provoking epigenetic theory.
Explains the Cambrian explosion from an entirely epigenetic view
Takes a causal rather than descriptive approach to the phenomenon
Allows for a broad readership, including those with only a basic biological knowledge, while maintaining scientific rigor
Автор: Torday John, Miller Jr William Название: Cellular-Molecular Mechanisms in Epigenetic Evolutionary Biology ISBN: 3030381323 ISBN-13(EAN): 9783030381325 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Chapter 1. Introduction
Chapter 2. Darwin, the Modern Synthesis, and a New Biology
Chapter 3. Cognition and the living condition
Chapter 4. What is consciousness? An Evolutionary Perspective
Chapter 5. Networking from the Cell to Quantum Mechanics as Consciousness
Chapter 6. The Nature of information and its communication
Chapter 7. The information cycle and biological information management
Chapter 8. Communication and the accumulation of genetic information
Chapter 9. Non-genic means of information reception and exchange
Chapter 10. The primacy of the unicellular state
Chapter 11. Phenotype, niche construction and natural cellular engineering
Chapter 12. Holobionts
Chapter 13. Four Domains: Cognition-based evolution
Chapter 14. Reconciling physics and biology
Chapter 15. What does this mean for evolution?
Chapter 16. Conclusion: Cellular-molecular evolution in the 21st century
Автор: Vladimir Botchkarev; Sarah Millar Название: Epigenetic Regulation of Skin Development and Regeneration ISBN: 3319167685 ISBN-13(EAN): 9783319167688 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists.
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