Автор: J. R. McGhee Название: Secretory Immunity and Infection ISBN: 1468433717 ISBN-13(EAN): 9781468433715 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The present conference is the third in a series on this topic sponsored by the NCP. The published proceedings will bring these to the attention of the research community quickly and hopefully they will stimulate new investigators to bring their talents to these problems.
Автор: Rolf Jessberger; Michael R. Lieber Название: Molecular Analysis of DNA Rearrangements in the Immune System ISBN: 3642501427 ISBN-13(EAN): 9783642501425 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The proteins that catalyze many steps of the process have now been identified by biochemical and genetic recon- stitution and by analysis of genetic mutants defective in V(D)J recombination. In addition to exciting progress in V(D)J recombination and class switch recombination, one chapter describes recent pro- gress in somatic hypermutation.
Автор: Mauro Bendinelli; Herman Friedman Название: Mycobacterium tuberculosis ISBN: 146845420X ISBN-13(EAN): 9781468454208 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Tuberculosis once again occupies a special position in the areas of infec- tious diseases and microbiology. Koch`s postulates were developed with tuberculosis in mind and became a focal point for many advances in microbiology and medicine.
Автор: Pramod K. Srivastava; Robert J. Binder Название: Heat Shock Proteins in the Immune System ISBN: 331969040X ISBN-13(EAN): 9783319690407 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Experts from around the world review the current field of the immunobiology of heat shock proteins, and provide a comprehensive account of how these molecules are spearheading efforts in the understanding of various pathways of the immune system.
Автор: Robert J. Binder; Pramod K. Srivastava Название: Heat Shock Proteins in the Immune System ISBN: 3030098621 ISBN-13(EAN): 9783030098629 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Experts from around the world review the current field of the immunobiology of heat shock proteins, and provide a comprehensive account of how these molecules are spearheading efforts in the understanding of various pathways of the immune system. This one-stop resource contains numerous images to both help illustrate the research on heat shock proteins, and better clarify the field for the non-expert. Heat shock proteins (HSPs) were discovered in 1962 and were quickly recognized for their role in protecting cells from stress. Twenty years later, the immunogenicity of a select few HSPs was described, and for the past 30 years, these findings have been applied to numerous branches of immunology, including tumor immunology and immunosurveillance, immunotherapy, etiology of autoimmunity, immunotherapy of infectious diseases, and expression of innate receptors. While HSPs can be used to manipulate immune responses by exogenous administration, they appear to be involved in initiation of de novo immune responses to cancer and likely in the maintenance of immune homeostasis.
Описание: Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration).
Автор: Richard Dunmur; Peter Ax Название: Multicellular Animals ISBN: 364205515X ISBN-13(EAN): 9783642055157 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The turtle, toothless, soft bodied, enclosed in boney, shell, is primordial and invincible, slow and changeless. Locked into turtles of time and tradition, inertia and ignorance, darkness and fear, we cajole and pull, struggle and push until we learn that ideas set us free. Fairbanks, Alaska University Campus Sculpture LIz BIESOT 1985 The evolutionary order of organisms as a product of Nature and its repre- sentation in a phylogenetic system as a construct of Man are two different things. The order in Nature consists of relationships between organisms. It is the result of an historic process that we call phylogenesis. When working with this order we must clearly differentiate between its identification and the subsequent description of what has been identified. When identifying the order we are placing ourselves in the framework of "hypothetical realism" (Vol. 1, p. 11); it is principally impossible to de- termine how well or how poorly the real world and our cognitive appara- tus match. For phylogenetics as an historicaUy directed discipline, how- ever, the following limitation is more relevant. We cannot demonstrate ex- perimentally wh ether or not that which we have interpreted from the prod- ucts of phylogenesis corresponds to facts of (hypothetical) reality.
Описание: The system of multicellular animals presented here is an alternative to the traditional classification system which still operates. This volume covers the metazoa from the molluscs up to the arthropods.
Автор: S. Kinsey; Peter Ax Название: Multicellular Animals ISBN: 3642086810 ISBN-13(EAN): 9783642086816 Издательство: Springer Рейтинг: Цена: 44582.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Those who wish for permanence in classifi- cation must pay the price of stasis - as if for- ever condemned to confound whales with fish. M. T. Ghiselin 1981, p. 283 Scientific argument is a debate concerned with the solution of unresolved problems. Before continuing with the phylogenetic system of the Metazoa this foreword gives me the opportunity to discuss some controversial ques- tions, to state selected positions more precisely and to remedy omissions. I would like to draw special attention to serious problems for phylogenetic systematics resulting from the inevitable confrontation with the current rules of nomenclature 1. In carrying out this debate, I hope not to lose the goodwill of those readers who are experts within the first few pages. A textbook for students? - Critics who ask that question and answer in the negative probably underestimate the open-mindedness of young people who are not troubled by, or can easily free themselves from, the restraints and arbitrariness of traditional classifications - and to whom systematics is offered as a scientific product in such a form that arguments for every single decision are comprehensible and checkable and can therefore be fully analyzed.
Автор: Escoll, Pedro Название: Bacterial Evasion of the Host Immune System ISBN: 1910190691 ISBN-13(EAN): 9781910190692 Издательство: Неизвестно Цена: 45980.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Infectious diseases continue to be a major threat to human health with predictions that these will account for one of five deaths globally over the coming decades. The worrying rise in antibiotic resistance in bacterial pathogens only serves to exacerbate this situation. Many pathogenic bacteria have evolved an array of sophisticated mechanisms to evade the host's immune response: some even exploit host functions to avoid detection by immune cells. Understanding the mechanisms of this subversion is critical for the understanding of bacterial pathogenesis and could be used for the development of novel antibacterial strategies. In this volumeexpert authors critically review the most important current research in this exciting field.
Topics include: the seven most important bacterial secretion systems; within-host envelope remodelling; subversion of macrophages; pathogen manipulation of host autophagy; mechanisms involved in sensing and restriction of bacterial replication; mechanisms of evasion by Salmonella; evasion strategies of mycobacteria; and role of Cyclic di-GMP in virulence and evasion of plant immune systems.
This text is essential reading for everyone involved in bacterial pathogenesis research and an invaluable reference work for those working in fields as diverse as medicine, biotechnology, agriculture, food and industry. A recommended acquisition for all microbiology laboratories.
Автор: Daisuke Kitamura Название: How the Immune System Recognizes Self and Nonself ISBN: 4431998314 ISBN-13(EAN): 9784431998310 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book surveys receptors used by immune cells, how they recognize self, nonself and "neoself" components, and how the immune system distinguishes the self and nonself - a far more complex process than a computer security system detecting infected documents.
Автор: Richard Dunmur; Peter Ax Название: Multicellular Animals ISBN: 3540001468 ISBN-13(EAN): 9783540001461 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The turtle, toothless, soft bodied, enclosed in boney, shell, is primordial and invincible, slow and changeless. Locked into turtles of time and tradition, inertia and ignorance, darkness and fear, we cajole and pull, struggle and push until we learn that ideas set us free. Fairbanks, Alaska University Campus Sculpture LIz BIESOT 1985 The evolutionary order of organisms as a product of Nature and its repre- sentation in a phylogenetic system as a construct of Man are two different things. The order in Nature consists of relationships between organisms. It is the result of an historic process that we call phylogenesis. When working with this order we must clearly differentiate between its identification and the subsequent description of what has been identified. When identifying the order we are placing ourselves in the framework of "hypothetical realism" (Vol. 1, p. 11); it is principally impossible to de- termine how well or how poorly the real world and our cognitive appara- tus match. For phylogenetics as an historicaUy directed discipline, how- ever, the following limitation is more relevant. We cannot demonstrate ex- perimentally wh ether or not that which we have interpreted from the prod- ucts of phylogenesis corresponds to facts of (hypothetical) reality.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
