Автор: Branton Daniel, Deamer David Название: Nanopore Sequencing: An Introduction ISBN: 9813270608 ISBN-13(EAN): 9789813270602 Издательство: Marston Book Services Рейтинг: Цена: от 4792.00 р. Наличие на складе: Есть
Описание:
This is an introductory text and laboratory manual to be used primarily in undergraduate courses. It is also useful for graduate students and research scientists who require an introduction to the theory and methods of nanopore sequencing. The book has clear explanations of the principles of this emerging technology, together with instructional material written by experts that describes how to use a MinION nanopore instrument for sequencing in research or the classroom.
At Harvard University the book serves as a textbook and lab manual for a university laboratory course designed to intensify the intellectual experience of incoming undergraduates while exploring biology as a field of concentration. Nanopore sequencing is an ideal topic as a path to encourage students about the range of courses they will take in Biology by pre-emptively addressing the complaint about having to take a course in Physics or Maths while majoring in Biology. The book addresses this complaint by concretely demonstrating the range of topics -- from electricity to biochemistry, protein structure, molecular engineering, and informatics -- that a student will have to master in subsequent courses if he or she is to become a scientist who truly understands what his or her biology instrument is measuring when investigating biological phenomena.
Автор: Vijg, Jan Название: Aging of the Genome ISBN: 0198569238 ISBN-13(EAN): 9780198569237 Издательство: Oxford Academ Рейтинг: Цена: 11563.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology.
Описание: The increased and widespread availability of large network data resources in recent years has resulted in the increased need for effective methods for the analysis of these networks. The challenge is to detect patterns that provide a better understanding of the data. However, this is not a straight forward task because of the size of the data sets and the computer power required for the analyses. The solution is to devise methods for approximately answering the questions posed, and these methods will vary depending on the data sets under scrutiny. This cutting-edge text introduces graph and network theory, cluster analysis and machine learning, before discussing the thought processes and creativity involved in the analysis of large-scale biological and medical data sets, using a wide range of real-life examples. Bringing together leading experts, this inter-disciplinary text provides an ideal introduction to and insight into the field of network data analysis.
Автор: Jeffrey Bennetzen; Sherry Flint-Garcia; Candice Hi Название: The Maize Genome ISBN: 3319974262 ISBN-13(EAN): 9783319974262 Издательство: Springer Рейтинг: Цена: 39130.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses advances in our understanding of the structure and function of the maize genome since publication of the original B73 reference genome in 2009, and the progress in translating this knowledge into basic biology and trait improvement. Maize is an extremely important crop, providing a large proportion of the world’s human caloric intake and animal feed, and serving as a model species for basic and applied research. The exceptionally high level of genetic diversity within maize presents opportunities and challenges in all aspects of maize genetics, from sequencing and genotyping to linking genotypes to phenotypes. Topics covered in this timely book range from (i) genome sequencing and genotyping techniques, (ii) genome features such as centromeres and epigenetic regulation, (iii) tools and resources available for trait genomics, to (iv) applications of allele mining and genomics-assisted breeding. This book is a valuable resource for researchers and students interested in maize genetics and genomics.
Описание: Bringing together leading experts in the field of network data analysis, this text introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning. Using real-world biological and medical examples, applications of these theories are discussed and creative thinking is encouraged in the analysis of such complex network data sets.
Автор: O`Riordan Kate Название: The Genome Incorporated: Constructing Biodigital Identity ISBN: 0754678512 ISBN-13(EAN): 9780754678519 Издательство: Taylor&Francis Рейтинг: Цена: 22968.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Examining the proliferation of human genomics across contemporary media cultures, this book engages with questions of what it means for a science to become so thoroughly part of every day life.
Автор: C. Nicolini Название: Genome Structure and Function ISBN: 0792345657 ISBN-13(EAN): 9780792345657 Издательство: Springer Рейтинг: Цена: 33821.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Covers the study of genome structure and function from primary to high order structures and gene expression in the control of cell function and cell cycle progression. This title emphasizes on an understanding of DNA structure and function in interphase and metaphase chromosomes.
For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions.
Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have engendered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field.
Автор: Saitou Название: Evolution of the Human Genome II ISBN: 4431569057 ISBN-13(EAN): 9784431569053 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Поставка под заказ.
Описание: It comprises twelve chapters divided into two parts discussing "Non-neutral Evolution on Human Genes" (Part I) and "Evolution of Modern Human Populations" (Part II.)The most significant feature of this book is the continent-wise discussion of modern human dispersal using human genomic data in Part II.
Автор: John M. Butler, Suzanne Bell Название: Understanding Forensic DNA ISBN: 100904401X ISBN-13(EAN): 9781009044011 Издательство: Cambridge Academ Рейтинг: Цена: 1899.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: How has DNA typing developed? How it is used in forensic science? What challenges have arisen? Written for a general audience, this volume illustrates concepts through examples, illustrations, and cases. It builds on this understanding to dispel misconceptions and explains the power as well as the limitations of DNA methods.
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