Описание: Due to the phylogenetic relationship and close genetic and biological similarities with humans, non-human primates (NHP) are regularly used in biomedical and behavioural research. However, because of their highly developed cognitive abilities and social skills, the use of these animals in biomedical research is debated more and more. Although it is acknowledged that in specific research areas NHP are still essential, it is recognised that the use of these animals can only be done under strict conditions under the most optimal welfare aspects. Welfare aspects include housing conditions, non-invasive methods and application of the 3Rs policy. Although many refinement methods have been described in nationally and internationally accepted guidelines on animal laboratory practice, recognition of the guidelines is unfortunately not universal. The present book covers a wide range of NHP models in preclinical research and welfare issues. The following chapters will cover: refinement of the use of NHP in biomedical research; NHP ethics and regulations in Europe; biological basis differences in the human and NHP; the major histocompatibility complex (MHC) immunology in NHP; stem cell biology in NHP; neuro and gliogenesis in an NHP ischemia stroke model; NHP models in autoimmune disease, organ transplantation and infectious disease research; viral diseases in NHP; NHP models in Parkinsons disease, in neurodegenerative disorders research and in cardio-cerebrovascular disease research; islet transplantation; ophthalmic diseases research and neurophysiology in NHP; transgenic engineering in NHP; NHP models of cancers; NHP models in respiratory disease research; NHP models in clinical and non-clinical pharmacology; NHP models in lung transplantation; and aging research in NHP. This book encapsulates a large volume of knowledge scientists have achieved in the field of nonhuman primate models in preclinical research. The editors have invited experts from the United States, Canada, and Europe to contribute 23 chapters in their respective fields of their expertise.
Автор: Carol A. Shively; Mark E. Wilson Название: Social Inequalities in Health in Nonhuman Primates ISBN: 331930870X ISBN-13(EAN): 9783319308708 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a comprehensive look atnonhuman primate social inequalities as models for health differences associated with socioeconomic status in humans.
Автор: Alexander Weiss; James E. King; Lindsay Murray Название: Personality and Temperament in Nonhuman Primates ISBN: 1461429714 ISBN-13(EAN): 9781461429715 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recently, there has been an increased interest in research on personality, temperament, and behavioral syndromes (henceforth to be referred to as personality) in nonhuman primates and other animals.
Описание: Despite many encouraging developments in the field of animal-free technologies, well-defined animal models are still needed to study fundamental properties of human diseases and to develop new prophylactic and therapeutic treatments against human diseases. Non-human primates (NHP) make up only a small, but important, part of the total number of animals used in biomedical and preclinical research. Due to their close phylogenetic relationship and the shared susceptibility to many human diseases, NHP can provide important research models to study these diseases and, as such, play a critical role in the advancement of various areas in the medical field. Studies in NHP have contributed to our understanding of various diseases and fundamental biological phenomena and they continue to be important in the development of new therapies, treatments, drugs and vaccines. Moreover, NHP models also contribute to our general knowledge of the processes that underlie non-disease and disease conditions. Important areas where NHP can provide important information include (emerging) infectious diseases, organ transplantation, neurological and aging-related disorders. Although not covered in this book due to time constraints, the need for, and benefits of, NHP models has been demonstrated most recently in the SARS-CoV-2 pandemic. The present book is the second of two volumes and covers important disease areas where NHP are used as model species. This volume includes different chapters on NHP models in infectious diseases, aging, neurodegenerative disorders, organ transplantation and cancer.
Описание: This book provides a comprehensive look at nonhuman primate social inequalities as models for health differences associated with socioeconomic status in humans. The benefit of the socially-housed monkey model is that it provides the complexity of hierarchical structure and rank affiliation, i.e. both negative and positive aspects of social status. At the same time, nonhuman primates are more amenable to controlled experiments and more invasive studies that can be used in human beings to examine the effects of low status on brain development, neuroendocrine function, immunity, and eating behavior. Because all of these biological and behavioral substrates form the underpinnings of human illness, and are likely shared among primates, the nonhuman primate model can significantly advance our understanding of the best interventions in humans.
This book proposes a detailed picture of the continuities and ruptures between communication in primates and language in humans. It explores a diversity of perspectives on the origins of language, including a fine description of vocal communication in animals, mainly in monkeys and apes, but also in birds, the study of vocal tract anatomy and cortical control of the vocal productions in monkeys and apes, the description of combinatory structures and their social and communicative value, and the exploration of the cognitive environment in which language may have emerged from nonhuman primate vocal or gestural communication.
Автор: G. C. Ruppenthal Название: Nursery Care of Nonhuman Primates ISBN: 1468434799 ISBN-13(EAN): 9781468434798 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The Infant Primate Research Laboratory at the University of Washington was conceived in 1970 as a small research Wlit primarily for support of two individual`s interests in early develop- ment of nonhuman primates.
Автор: Gene P. Sackett; Gerald Ruppenthal; Kate Elias Название: Nursery Rearing of Nonhuman Primates in the 21st Century ISBN: 1489992065 ISBN-13(EAN): 9781489992062 Издательство: Springer Рейтинг: Цена: 39130.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: - Preface. -Introduction to Section 1. -The Effects of Rearing Experiences: The Early Years. -The Changing Role of Hand-Rearing in Zoo-Based Primate Breeding Programs. -Animal Welfare Regulations and Nursery Rearing. -Data Management for the Nonhuman Primate Nursery. -Very Early Rearing Experience: Rationale and Methodologies for Studying Prenatal Development in Nonhuman Primates. -Introduction to Section 2. -The Effect of Hand-Rearing on the Sexual and Maternal Competence of Three Species of Lemurs: Varecia variegate, Varecia rubra, and Eulemur macaco. -Nursery-Reared Prosimian Primates. -Hand-Rearing of Infant Common Marmosets (Callithrix jacchus). -Introduction to Section 3. -Immunological Consequences of Nursery Rearing. -Special Challenges of Rearing Infant Macaques Infected with Lentivirus (SIV, HIV, SHIV). -Nursery Rearing and Biobehavioral Organization. -Introduction to Section 3. -Neurobehavioral Assessment of Nonhuman Primate Neonates. -Is it Nutrients or Nurturing?: Comparison of the Growth and Development of Mother-Reared and Laboratory-Reared Macaque Infants. -Baboon Nursery Rearing Practices and Comparisons between Nursery- and Mother-Reared Individuals. -Early Rearing Conditions and Captive Chimpanzee Behavior: Some Surprising Findings. -Effects of Early Rearing History on Growth and Behavioral Development in Captive Chimpanzees (Pan troglodytes). -Introduction to Section 4. -Squirrel Monkeys as an Example of Primate Nursery Medicine. -Nursery Care of At-Risk Nonhuman Primates. -A Quick and Effective Method for Establishing Self-Feeding in Stump-Tailed Macaques (Macaca arctoides). -Saliva as a Medium for Assessing Cortisol and other Compounds in Nonhuman Primates: Collection, Assay, and Examples. -The SPIT Method: For Simultaneous and Unobtrusive Collection of Salivary Cortisol from Individually Housed Infant Monkeys. -Actimetry Measurement of Behavioral Regulation and Sleep Cycles in InfantRhesus Macaques (Macaca mulatta). -Noninvasive Neuroimaging Techniques for the Study of Primate Brain Development. -Tethering with Maternal and Fetal Catheterization: Technology and Theory for Studying Pre- to Postnatal Continuities. -Introduction to Section 5. -Hematology and Serum Chemistry in Young Captive Chimpanzees (Pan troglodytes). -Hematology and Serum Chemistry Reference Values for Rhesus Macaque. - Hematology and Serum Chemistry Reference Values for Pigtailed Macaque (Macaca nemestrina) Infants. -Hematology and Serum Chemistry Reference Values for Mother-Reared Squirrel Monkey (Saimiri boliviensis boliviensis) Infants. -Index.
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