Physical Exercise and Natural and Synthetic Products in Health and Disease, Guest
Автор: Li Название: Total Synthesis of Natural Products ISBN: 3642340644 ISBN-13(EAN): 9783642340642 Издательство: Springer Рейтинг: Цена: 9782.00 р. 13974.00-30% Наличие на складе: Есть (1 шт.) Описание: Written by experts in organic chemistry, this book covers a range of natural products, from steroids to alkaloids. Coverage details the biological and pharmacological properties of the natural product and outlines current total synthesis procedures.
Описание: In a classical alphabetical format, this two-volume reference covers more than 1000 painstakingly screened natural product structures. For each compound or compound class, a basic chemical characterization is given, followed by a description of the biological source and a discussion of their pharmaceutical potential as lead molecules for new drugs.
Описание: With contributions from leading academics around the world, this book makes a ground-breaking contribution to the field of biocatalysis and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.
Описание: This detailed book explores protocols with the aim of testing aerobic exercise, resistance training, special diets, additives and natural products, which have led to new insights into the physiological and molecular aspects of health and disease. Many of these approaches have contributed to significant improvements in disease areas such as cardiovascular disease, cognitive dysfunction, diabetes, frailty, gliobastoma, metabolic syndrome, obesity, oxidative stress, and various cancers. This collection also provides important information on disease mechanisms and novel drug targets as each protocol is presented in the context of specific chronic diseases or different therapeutic areas. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and reflective of research from all around the globe, Physical Exercise and Natural and Synthetic Products in Health and Disease serves as an ideal guide for researchers in the areas of chronic disease, exercise, and nutrition, as well as to clinical scientists, physicians, and pharmacologists as it gives insights into possibilities for the development of novel therapeutics and the means of monitoring therapeutic response through the measurement of molecular and physiometric biomarkers.
Описание: A comprehensive reference on the synthetic chemistry of cycloaddition reactions Dipolar cycloaddion reactions have found many useful applications in chemistry, particularly with respect to the synthesis of compounds with new chiral centers. Such asymmetric syntheses have a growing importance in the pharmaceutical and agricultural industries with respect to the preparation of chiral drugs and natural products. This much-needed volume updates the popular 1984 edition with advances made over the last twenty years in cycloaddition reactions. While the 1984 volume focused on theory, structure, reactivities, and selectivities, the new volume is geared toward synthetic applications. Both carbonyl ylides and nitronates, important members of the 1,3-dipole family that were not reviewed previously, are now included. Also, beyond the capability of the 1,3-dipolar cycloadditon reaction to produce heterocycles, the ability of heteroatom-containing cycloadducts to transform into a variety of other functionalized organic molecules, cylclic or acyclic, and the ability of many 1,3-dipolar cycloadditions to generate rings containing several contiguous stereocenters in one synthetic operation is discussed. Volume 59 provides the only comprehensive reference on the market detailing the synthetic chemistry of cycloaddition reactions.
Описание: Introduction.- Synthesis of the Tridachiahydropyrones and their Biomimetic Precursors.- Interactions of the Tridachiahydropyrones with Model Membrane Systems: Biophysical Studies.- Investigations into the Photoprotective and Antioxidant Properties of the Tridachiahydropyrones.- Summary and Conclusions.- Experimental.- Synthesis of Alkenyl Nitriles by the Palladium-Catalysed Cyanation of Vinyl Halides with Acetone Cyanohydrin.
Автор: Luzzio, Frederick Название: Imides ISBN: 0128156759 ISBN-13(EAN): 9780128156759 Издательство: Elsevier Science Рейтинг: Цена: 29476.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Imides: Medicinal, Agricultural, Synthetic Applications and Natural Products Chemistry provides a comprehensive overview of imides being developed as pharmaceuticals or experimental therapeutics. Featuring a diverse range of experts in the field of imides, each chapter reviews the state-of-the-art, including the isolation and identification of naturally-occurring imides, as well as the total synthesis of imide natural products. As there is a need for a comprehensive review of imides as a class of naturally-occurring, biologically active molecules, this book will be invaluable to those in pharmaceuticals, academia, and anyone looking for clinical applications.
Features cutting-edge research in the field of imides for pharmaceutical and experimental therapeutic applications
Includes coverage of naturally occurring imides, along with medicinal chemistry-inspired imides
Focuses on the presentation of selected targets for their complex multistep synthesis
Discusses new reagents and strategies for synthesis
Includes contributions from leading experts in the field of imide research, working in both natural product chemistry and medicinal chemistry
Название: Antimicrobials ISBN: 0367377152 ISBN-13(EAN): 9780367377151 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Antimicrobials: Synthetic and Natural Compounds summarizes the latest research regarding the possibilities of the most important natural antimicrobial compounds derived from various plant sources containing a wide variety of secondary metabolites. With collected contributions from international subject experts, it focuses primarily on natural products as a source of bioactive compounds that may be active against multidrug-resistant pathogens, providing an alternative to established antibiotics in controlling infectious diseases.
Covering a wide range of marine, microbial, and plant-origin antimicrobials, the book examines the usefulness of plant products containing antimicrobial molecules against bacteria, fungi, protozoa, and viruses. It also reports on unusual sources of antimicrobials such as animal fecal actinomycetes, actinobacteria, and cyanobacteria and discusses synthetic chemical compounds and biogenic nanoparticles.
The number of drug-resistant bacteria is increasing, posing a major problem to modern medicine. This book explores an important topic: finding and applying alternative means of pathogenic control and treatment via natural sources. It is an important source of information for microbiologists, biotechnologists, biochemists, pharmacologists, botanists, marine biologists, and others involved in research on natural and synthetic antimicrobial compounds. It is also a useful resource for scholars, scientists, academics, and students in various science disciplines.
Описание: Introduction.- Synthesis of the Tridachiahydropyrones and their Biomimetic Precursors.- Interactions of the Tridachiahydropyrones with Model Membrane Systems: Biophysical Studies.- Investigations into the Photoprotective and Antioxidant Properties of the Tridachiahydropyrones.- Summary and Conclusions.- Experimental.- Synthesis of Alkenyl Nitriles by the Palladium-Catalysed Cyanation of Vinyl Halides with Acetone Cyanohydrin.
Описание: The aim of this volume is to underline that promoting physical activity is crucial to preventing illness and maintaining our health, thus leading to a reduction in healthcare costs. Physical activity therefore helps in tackling today`s major health challenges, including diabetes, high blood pressure, and cardiorespiratory diseases.
This 8-volume set provides a systematic description on 8,350 active marine natural products from 3,025 various kinds of marine organisms. The diversity of structures, biological resources and pharmacological activities are discussed in detial. Molecular structural classification system with 264 structural types are developed in the book as well. The 1st volume mainly illustrates the molecular formula and structures of terpenoids.
Автор: Sarker, Satyajit Dey Название: Medicinal Natural Products: A Disease-Focused Approach,55 ISBN: 0128210192 ISBN-13(EAN): 9780128210192 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Medicinal Natural Products: A Disease-Focused Approach, Volume 55 of the Annual Reports in Medicinal Chemistry series, highlights the applications of natural products as medicines or prospective medicinal leads for the treatment of various human ailments. Each chapter covers a particular disease area or medical condition - for example, the chapter on anticancer natural products will look into the contributions of natural products in cancer chemotherapy, including the discovery and development of taxol, vincristine and vinblastine as cancer chemotherapeutic agents, and also explore the recent developments in anticancer drug discovery and development from various natural products. All 16 chapters will cover the history, current status and future opportunities of natural products in the treatment and prevention of any particular ailment or medical conditions. Whist the primary focus will be on the medicinal chemistry aspects of these natural products with therapeutic applications, structural modifications and in silico approaches will also be covered. Additionally all chapters will review recent literature of last ten years or so, and present an overview on the developments in respective areas.
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