Описание: With a focus on practical applications of biophysical techniques, Biophysical Methods for Biotherapeutics helps formulation and analytical scientists in pharma and biotech better understand and use biophysical methods. Author Tapan K.
Presents Practical Applications of Mass Spectrometry for Protein Analysis and Covers Their Impact on Accelerating Drug Discovery and Development
Covers both qualitative and quantitative aspects of Mass Spectrometry protein analysis in drug discovery
Principles, Instrumentation, Technologies topics include MS of peptides, proteins, and ADCs, instrumentation in protein analysis, nanospray technology in MS protein analysis, and automation in MS protein analysis
Details emerging areas from drug monitoring to patient care such as Identification and validation of biomarkers for cancer, targeted MS approaches for biomarker validation, biomarker discovery, and regulatory perspectives
Brings together the most current advances in the mass spectrometry technology and related method in protein analysis
Автор: Sandeep Kumar Название: Developability of Biotherapeutics: Computational Approaches ISBN: 1482246139 ISBN-13(EAN): 9781482246131 Издательство: Taylor&Francis Рейтинг: Цена: 24499.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Biopharmaceuticals are emerging as frontline medicines to combat several life-threatening and chronic diseases. However, such medicines are expensive to develop and produce on a commercial scale, contributing to rising healthcare costs. Developability of Biotherapeutics: Computational Approaches describes applications of computational and molecular modeling techniques that improve the overall process of discovery and development by removing empiricism.
The concept of developability involves making rational choices at the pre-clinical stages of biopharmaceutical drug development that could positively impact clinical outcomes. The book also addresses a general lack of awareness of the many different contributions that computation can make to biopharmaceutical drug development.
This informative and practical reference is a valuable resource for professionals engaged in industrial research and development, scientists working with regulatory agencies, and pharmacy, medicine, and life science students and educators. It focuses primarily on the developability of monoclonal antibody candidates, but the principles described can also be extended to other modalities such as recombinant proteins, fusion proteins, antibody drug conjugates and vaccines.
The book is organized into two sections. The first discusses principles and applications of computational approaches toward discovering and developing biopharmaceutical drugs. The second presents best practices in developability assessments of early-stage biopharmaceutical drug candidates.
In addition to raising awareness of the promise of computational research, this book also discusses solutions required to improve the success rate of translating biologic drug candidates into products available in the clinic. As such, it is a rich source of information on current principles and practices as well as a starting point for finding innovative applications of computation towards biopharmaceutical drug development.
Название: Water Insoluble Drug Formulation, 3 ISBN: 149872941X ISBN-13(EAN): 9781498729413 Издательство: Taylor&Francis Рейтинг: Цена: 39811.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Water-Insoluble Drug Formulation, Third Edition serves as a comprehensive reference for pharmaceutical scientists in the handling of formulation issues related to water-insoluble drugs.
Автор: Ajit S Narang; Sai H S. Boddu Название: Excipient Applications in Formulation Design and Drug Delivery ISBN: 331937107X ISBN-13(EAN): 9783319371078 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In recent years, emerging trends in the design and development of drug products have indicated ever greater need for integrated characterization of excipients and in-depth understanding of their roles in drug delivery applications.
Описание: This book treats the derivation and implementation of a unified particle finite element formulation for the solution of fluid and solid mechanics, Fluid-Structure Interaction (FSI) and coupled thermal problems.FSI problems are involved in many engineering branches, from aeronautics to civil and biomedical engineering. The numerical method proposed in this book has been designed to deal with a large part of these. In particular, it is capable of simulating accurately free-surface fluids interacting with structures that may undergo large displacements, suffer from thermo-plastic deformations and even melt. The method accuracy has been successfully verified in several numerical examples. The thesis also contains the application of the proposed numerical strategy for the simulation of a real industrial problem. This thesis, defended at the Universitat Politecnica de Catalunya in 2015, was selected (ex aequo) as the best PhD thesis in numerical methods in Spain for the year 2015 by the Spanish Society of Numerical Methods in Engineering (SEMNI).
Автор: Mindess, Sidney Название: Developments in the Formulation and Reinforcement of Concrete ISBN: 0081026161 ISBN-13(EAN): 9780081026168 Издательство: Elsevier Science Рейтинг: Цена: 38739.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
In the first edition of this book, Developments in the Formulation and Reinforcement of Concrete, a number of what are often referred to as "specialty" concretes were discussed. These concretes through specialty mix design offer high physical properties and enhanced performance. The information discussed in these chapters is still relevant today, but in the ten years since the first edition was published, a number of other key areas have become increasingly important in modern concrete technology. There is now much more emphasis on sustainability within the cement and concrete industries. This requires a greater emphasis and understanding of some of the major durability problems that the scientist or engineer may encounter, such as chloride corrosion of steel, and alkali-aggregate reactions. There is also increasing use of specifications involving explicit service life requirements (100 years being common), but this is a concept that is still widely misunderstood.
In this second edition of the book all material previously covered on specialty concretes is brought fully up-to-date taking into consideration latest developments and with the addition of new chapters on supplementary cementitious materials; mass concrete; the sustainably of concrete; service life prediction; limestone cements; corrosion of steel in concrete; alkali-aggregate reactions and concrete as a multiscale material the chapters will introduce the reader to some of the most important issues facing the concrete industry today. In keeping with the previous edition, the international team of contributors, are all at the cutting edge in their own areas of research and have wide industrial experience.
With its distinguished editor and international team of contributors, Developments in the Formulation and Reinforcement of Concrete, Second Edition is a standard reference for civil and structural engineers.
Summarizes a wealth of recent research on structural concrete including material microstructure, concrete types, variation and construction techniques
Emphasizes concrete mixture design and applications in civil and structural engineering
Reviews modern concrete materials to novel construction systems, such as the precast industry and structures requiring high-performance concrete
Автор: Burnett Ned Название: Drug Formulation Design and Drug Delivery ISBN: 1632425726 ISBN-13(EAN): 9781632425720 Издательство: Неизвестно Цена: 24140.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Tadros Tharwat F. Название: Basic Principles of Formulation Types ISBN: 3110587483 ISBN-13(EAN): 9783110587487 Издательство: Walter de Gruyter Цена: 69890.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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