Platinum-Based Chemotherapy: Clinical Uses, Efficacy and Side Effects, Kulmira Nurgali, Raquel Abalo Delgado
Автор: Priestman Название: Cancer Chemotherapy in Clinical Practice ISBN: 1846289890 ISBN-13(EAN): 9781846289897 Издательство: Springer Рейтинг: Цена: 3390.00 р. Наличие на складе: Есть (2 шт.) Описание: Summarizes a range of systemic cancer therapies, explaining their mode of action and potential side-effects, as well as their clinical applications. This text explains the principles underlying cancer chemotherapy. It also explains the place of drug treatment, and the outcomes that can be expected from chemotherapy, in major cancers.
Автор: Priestman, Terrence Название: Cancer Chemotherapy in Clinical Practice ISBN: 0857297260 ISBN-13(EAN): 9780857297266 Издательство: Springer Рейтинг: Цена: 8384.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A simple introduction explaining the broad principles underlying chemotherapy, this book gives trainees a framework within which they can place the specific aspects of cancer chemotherapy they encounter in their everyday experience.
Автор: Karp Название: Handbook Targeted Cancer Therapy 3E Pb ISBN: 1975179242 ISBN-13(EAN): 9781975179243 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 10294.00 р. Наличие на складе: Есть (1 шт.) Описание:
Designed for quick, everyday reference, Handbook of Targeted Cancer Therapy and Immunotherapy, 3rd Edition, includes clinical trial results of more than 250 state-of-the-art targeted therapy and immunotherapy agents, providing a practical, intuitive, colorful overview of this rapidly advancing field. Comprehensive yet concise, this easy-access resource by Drs. Daniel D. Karp, Gerald S. Falchook, and JoAnn D. Lim, helps you navigate through the newest research reports and apply the most recent discoveries as they pertain to specific tumor types, actionable molecular targets, and clinical performance of investigational targeted agents and combinations of agents. This handbook presents information distilled by dozens of translational research clinicians and other healthcare experts with hundreds of years of cumulative experience in the revolutionary area of genomically based precision oncology.
Covers cancer targets—phase 1, 2, and 3 trials and preliminary results, as well as approved therapies.
Includes sections on Molecular Targets and Pathways, and Targeted and Immunotherapy Agents.
Contains a section on Carcinogenesis from the Perspective of Targeted Therapy and Immunotherapy, with essential content on biology, immunology, and immunotherapy.
Organizes information by tumor type, pathway, and drug name, so you can approach clinical challenges from any direction.
Highlights FDA approvals throughout.
Pocket-sized and color coded to help you find information quickly and easily.
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Автор: William Kevin Kelly, Susan Halabi Название: Oncology Clinical Trials: Successful Design, Conduct, and Analysis ISBN: 0826168728 ISBN-13(EAN): 9780826168726 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 23199.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The second edition of Oncology Clinical Trials has been thoroughly revised and updated and now contains the latest designs and methods of conducting and analyzing cancer clinical trials in the era of precision medicine with biologic agents—including trials investigating the safety and efficacy of targeted therapies, immunotherapies, and combination therapies as well as novel radiation therapy modalities. Now divided into five sections this revamped book provides the necessary background and expert guidance from the principles governing oncology clinical trials to the innovative statistical design methods permeating the field; from conducting trials in a safe and effective manner, analyzing and interpreting the data, to a forward-looking assessment and discussion of regulatory issues impacting domestic, international, and global clinical trials.Considered by many as the gold standard reference on oncology clinical trials in the field, the second edition continues to provide examples of real-life flaws and real-world examples for how to successfully design, conduct and analyze quality clinical trials and interpret them. With chapters written by oncologists, researchers, biostatisticians, clinical research administrators, and industry and FDA representatives, this volume provides a comprehensive guide in the design, conduct, monitoring, analysis, and reporting of clinical trials in oncology.New to this Edition:Outlines how to design clinical trials with and without biomarker testing—including genomics-based “basket” trials, and adaptive trials for all phases during treatment and quality-of-life trialsIncludes new chapters on immunotherapy trials, radiation therapy trials, multi-arm trials, meta-analysis and adaptive design, use of genomics, dose modifications and use of ancillary treatments in investigational studies, establishing surrogate endpoints, practical issues with correlative studies, cost-effectiveness analysis, and moreComprehensively covers all regulatory aspects in the pursuit of global oncology trialsDigital Access to the eBook included
Автор: Temple Amy Название: Clinical Aspects of Neoadjuvant Chemotherapy ISBN: 1632420813 ISBN-13(EAN): 9781632420817 Издательство: Неизвестно Цена: 19955.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Taken together the data presented in this review, and work by many other investigators, support the notion that DNA excision repair is important in a tumor cell`s resistance to platinum compounds.
Автор: Christine S. Walsh Название: Clinical Trials in Ovarian Cancer ISBN: 081358647X ISBN-13(EAN): 9780813586472 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 18810.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: When a patient is diagnosed with a gynecological malignancy, she and her doctors must make urgent, high-risk decisions about her course of treatment. In selecting an appropriate plan of care, physicians must weigh the patient's individual needs, the tumor's specific characteristics, and the treatment's potential side effects. Because there is no one-size-fits-all treatment solution, a plethora of clinical trials have been performed on ovarian cancer patients, but clinicians may struggle to keep up with this ever-growing body of research. Collecting and synthesizing research findings from a wide array of medical journal articles and book chapters, Clinical Trials in Ovarian Cancer provides physicians with an invaluable resource. Gynecologic oncologist Christine S. Walsh systematically outlines each of the seminal Phase III trials that have shaped the treatment of ovarian cancers, detailing the rationale for the trial, the patient population studied, treatment delivery methods, efficacy, toxicity, and trial conclusions. She provides a clear overview of established treatments, as well as still-controversial experimental approaches. The first book to organize this cutting-edge research into an easy-to-use reference, Clinical Trials in Ovarian Cancer should help medical personnel at all levels provide their patients with the highest standard of care.
Автор: Raj Nair, Rene-Jean Bensadoun Название: Mitigation of Cancer Side Effects using Light ISBN: 1681740117 ISBN-13(EAN): 9781681740119 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 4389.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book the authors attempt to portray the current status of the supportive care interventions that are possible with photobiomodulation using low level laser therapy (LLLT) in patients undergoing cancer treatment for solid tumours, harmatological malignancies, and head and neck cancers.
Автор: Etienne Baulieu; Donald T. Forman; Magnus Ingelman Название: Ruthenium and Other Non-Platinum Metal Complexes in Cancer Chemotherapy ISBN: 3642747620 ISBN-13(EAN): 9783642747625 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Andrea Bonetti; Roberto Leone; Franco Muggia; Step Название: Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy ISBN: 1493957104 ISBN-13(EAN): 9781493957101 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cisplatin, the first member of the family of platinum-containing chemotherapeutic agents, was discovered by Barnett Rosenberg in 1965 and approved by the FDA for marketing in 1978. After 30 years of use in the clinic, cisplatin remains a central element of many treatment regimens. Cisplatin is still an irreplaceable component of a regimen that produces high cure rates in even advanced nonseminomatous germ-cell cancers, and is widely used in the treatment of ovarian cancers and other gynecologic cancers, head and neck, and numerous other tumor types. The development of carboplatin has reduced some of the adverse events associated with cisplatin treatment, and the introduction of the DACH platinum compound oxaliplatin has broadened the spectrum of activity of the platinums to include gastro-intestinal cancers, especially colorectal cancer. The clinical importance of this family of drugs continues to drive investigation into how these drugs work and how to improve their efficacy and reduce their toxicity. The papers in this volume were presented in Verona, Italy, during the tenth International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy. The symposium was jointly organized by the Department of Oncology of the Mater Salutis Hospital – Azienda Sanitaria Locale 21 of the Veneto Region – and by the Department of Medicine and Public Health, Section of Pharmacology, the University of Verona. They reflect the vitality of this field and the increasing use of new molecular and cell biologic, genetic, and biochemical tools to identify approaches to further improve their use.
Автор: Leonard B. Saltz Название: Colorectal Cancer ISBN: 1617377562 ISBN-13(EAN): 9781617377563 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Management options for patients with colorectal cancer have undergone d- matic changes over the past decade. Whereas at the start of 1996 only one drug, 5-Fluorouracil, was available for the treatment of this disease, a mere 10 yr later, six drugs are licensed for use in colorectal cancer, and others are in the late phases of clinical development.
Автор: Casini Angela, Vessieres Anne, Meier-Menches Samuel M. Название: Metal-Based Anticancer Agents ISBN: 1788014065 ISBN-13(EAN): 9781788014069 Издательство: Royal Society of Chemistry Рейтинг: Цена: 37805.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts, enabling methods, and key pre-clinical and clinical aspects.
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