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Chromatin And Epigenetics: An Introduction To Epigenetic Mechanisms, Vincenzo Pirrotta


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Автор: Vincenzo Pirrotta
Название:  Chromatin And Epigenetics: An Introduction To Epigenetic Mechanisms
ISBN: 9789811257629
Издательство: World Scientific Publishing
Классификация:


ISBN-10: 9811257620
Обложка/Формат: Hardback
Страницы: 524
Вес: 0.00 кг.
Дата издания: 31.07.2023
Язык: English
Размер: 159 x 237 x 37
Ключевые слова: DNA & Genome, MEDICAL / Genetics,SCIENCE / Life Sciences / Cell Biology,SCIENCE / Life Sciences / Genetics & Genomics
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Поставляется из: Англии
Описание: This book is an introduction to epigenetics, a controversial term that denotes the mechanisms that instruct the genome on how to express the purely genetic information that encodes proteins. Starting with the discovery of repressor proteins in the 1960s, epigenetics evolved into a kind of user manual for the genetic information, telling the genome if, when, how much and in what cells to read genes. Advances in epigenetics in the past 15 years have revealed how it lies at the heart of virtually every branch of biological and medical sciences and an understanding of its basic principles is therefore essential for every student in this field.The field of chromatin and epigenetics has developed very rapidly in the past 15-20 years. The pace in the field of epigenetics has now slowed down, the basic outlines of the mechanisms and implications have solidified and a consensus has been achieved among the researchers in the field. At the same time, these mechanisms and implications are now an integral part of how we think about the genome. Genes are more than just DNA and more than just protein-coding sequences and this realization has revolutionized our understanding of the genome, gene expression and its regulation in development, health and disease. It is time, therefore, for a textbook to help train a new generation of biologists and health scientists as well as providing a basic competence among practitioners in allied fields. The present book has grown out of a course given for the past 13 years to advanced undergraduates at Rutgers University. In keeping with the experience in that course, the book is abundantly illustrated, presents a wealth of specific examples, and includes a chapter describing a number of methods and techniques that have driven the advances in the field.


Ferguson-NUTRITIONAL EPIGENOMICS

Автор: Ferguson, Bradley
Название: Ferguson-NUTRITIONAL EPIGENOMICS
ISBN: 0128168439 ISBN-13(EAN): 9780128168431
Издательство: Elsevier Science
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Цена: 26444.00 р.
Наличие на складе: Поставка под заказ.

Описание:

Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition's role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet's role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders.

Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease.

  • Empowers the reader to employ nutritional epigenomics approaches in their own research
  • Discusses the latest topics in nutritional epigenomics in the regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and disease
  • Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies
Epigenetics: How Environment Shapes Our Genes

Автор: Francis Richard C.
Название: Epigenetics: How Environment Shapes Our Genes
ISBN: 039334228X ISBN-13(EAN): 9780393342284
Издательство: Wiley
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Цена: 2058.00 р.
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Описание: Goodbye, genetic blueprint. . . . The first book for general readers on the game-changing field of epigenetics.

Epigenetics of Aging and Longevity

Автор: Moskalev, Alexey
Название: Epigenetics of Aging and Longevity
ISBN: 0128110600 ISBN-13(EAN): 9780128110607
Издательство: Elsevier Science
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Цена: 19875.00 р.
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Описание:

Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses--including cancer and cardiovascular, metabolic, and neurodegenerative diseases--are explored in detail.

This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease.

The Developing Genome: An Introduction to Behavioral Epigenetics

Автор: Moore David S.
Название: The Developing Genome: An Introduction to Behavioral Epigenetics
ISBN: 0199922349 ISBN-13(EAN): 9780199922345
Издательство: Oxford Academ
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Цена: 8554.00 р.
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Описание: An accessible introduction to behavioral epigenetics, The Developing Genome explores how experiences influence genetic activity. We develop as we do not because of the genes we have, but because of what our genes do.

Introduction to Epigenetics

Автор: Paro Renato, Grossniklaus Ueli, Santoro Raffaella
Название: Introduction to Epigenetics
ISBN: 3030686698 ISBN-13(EAN): 9783030686697
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Murder seems to follow young Tommy McBride everywhere. Only five years after the death of his family, a freak accident on a sheep station sends him fleeing into the wilderness of the Australian outback, the station overseer lying dead behind him with his head smashed on a rock. But Tommy is haunted by more than the death of his family - both he and his brother Billy witnessed a vicious state-sanctioned massacre of the Kurrong people, and they havent seen each other since.When an official inquiry is launched into the slaughter, the successful life that Billy has built for himself is under threat. He desperately needs to find his brother, long

Developing genome

Автор: Moore, David S.
Название: Developing genome
ISBN: 0190675659 ISBN-13(EAN): 9780190675653
Издательство: Oxford Academ
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Цена: 3642.00 р.
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Описание: An accessible introduction to behavioral epigenetics, The Developing Genome explores how experiences influence genetic activity. We develop as we do not because of the genes we have, but because of what our genes do. The Developing Genome explains this new discipline and its revolutionary implications, changing how we understand development and evolution.

Epigenetics and Pathology: Exploring Connections Between Genetic Mechanisms and Disease Expression

Автор: Kasirajan Ayyanathan
Название: Epigenetics and Pathology: Exploring Connections Between Genetic Mechanisms and Disease Expression
ISBN: 1926895789 ISBN-13(EAN): 9781926895789
Издательство: Taylor&Francis
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Цена: 20671.00 р.
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Описание:

This title includes a number of Open Access chapters.

This important book explores recent research by experts in the field pertaining to the role played by genetic factors in human pathology. A range of perspectives creates a well-rounded picture, including:

  • host-pathogen interactions
  • causal relationships between genes and the environment
  • the effects of environmental chemicals on gene expression
  • DNA methylation

The book also covers the analysis and provides models for understanding the epigenetics-pathology connection.

This book is designed for use by senior undergraduate and graduate students from several disciplines such as general, molecular, cellular biology, genetics, genomics, proteomics, and bioinformatics. It will also serve as a reference book for existing researchers and new investigators entering this rather unexplored field.

Blinded by Science

Автор: Wastell David
Название: Blinded by Science
ISBN: 1447322347 ISBN-13(EAN): 9781447322344
Издательство: Marston Book Services
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Цена: 5938.00 р.
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Описание: This timely book critically examines the capabilities and limitations of new areas of biology, especially epigenetics and neuroscience, that are used as powerful arguments for developing social policy in a particular direction, exploring their implications for policy and practice.

Nutrition, Epigenetics and Health

Автор: Burdge Graham, Lillycrop Karen
Название: Nutrition, Epigenetics and Health
ISBN: 9813143304 ISBN-13(EAN): 9789813143302
Издательство: World Scientific Publishing
Цена: 13781.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This book will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.

Specific Gene Expression and Epigenetics: The Interplay Between the Genome and Its Environment

Автор: Ayyanathan Kasirajan
Название: Specific Gene Expression and Epigenetics: The Interplay Between the Genome and Its Environment
ISBN: 1771880368 ISBN-13(EAN): 9781771880367
Издательство: Taylor&Francis
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Цена: 18374.00 р.
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Описание:

This title includes a number of Open Access chapters.

This new volume on gene expression and epigenetics discusses environmental effects related to specific gene expression. The book also shows methods for bioinformatic analysis of the epigenome. The book is broken into two sections: the first looks at eukaryotic DNA methylation and the second addresses how to integrate genomic medicine into clinical practice.

The book includes chapters on these topics:

- Gene expression in colon cancer tissue

- Epigenetics in human acute kidney injury

- Embryologically relevant candidate genes in MRKH patients

- DNA methylation in common skeletal disorders

- Causal relationships in genomics

- Predicting severe asthma exacerbations in children

- Epigenetic understanding of gene-environment interactions in psychiatric disorders

Автор: Lux, Vanessa
Название: Psychobiological Development
ISBN: 1138699438 ISBN-13(EAN): 9781138699434
Издательство: Taylor&Francis
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Цена: 4592.00 р.
Наличие на складе: Нет в наличии.

Political biology

Автор: Meloni, Maurizio
Название: Political biology
ISBN: 1137377712 ISBN-13(EAN): 9781137377715
Издательство: Springer
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Цена: 12157.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book explores the socio-political implications of human heredity from the second half of the nineteenth century to the present postgenomic moment. It discusses eugenics, the modern synthesis, and epigenetics. Meloni argues that thanks to findings in epigenetics we may be witnessing a return to `soft heredity`.


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