Описание: This book of the series on “Advances in Biochemistry in Health and Disease” includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters. This book has been organized into three sections: (i) General Implications of RAS in human health and Infectious Diseases, (ii) Lung, Liver and Kidney Diseases, and (iii) Development of Cancer. Each chapter has discussed comprehensive knowledge regarding the molecular and cellular aspects of the role of RAS in the pathophysiology and pharmacotherapy of different disease processes. Biochemical mechanisms associated with angiotensin II type 1 and type II receptors, and angiotensin (1-7) MAS receptors for the occurrence of both harmful and beneficial effects of prolonged activation of RAS in different diseases have been outlined. It is noteworthy to point out that different chapter in this book were prepared by recognized global expertise in the area of inflammation, oxidative stress and signal transduction pathways to highlight the role of RAS in different diseases. It is our sincere hope that this book will be of great interest to both biomedical investigators and health professionals as well as graduate students and postdoctoral fellows all over the world.
Автор: J.M. Saavedra; P.B.M.W.M. Timmermans Название: Angiotensin Receptors ISBN: 1461360498 ISBN-13(EAN): 9781461360490 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: From molecular biology to clinical applications of selective receptor blockade, the present volume compiles the latest advances of this emerging field. Of particular importance is the attention given to the newly discovered AT2 receptors, and the physiology and pathophysiology of angiotensin receptor subtypes. The book will provide clinicians treating cardiovascular disease and hypertension with a clearer understanding of this therapeutically important and complicated hormone.
Автор: Walmor C. DeMello; Edward D. Frohlich Название: Renin Angiotensin System and Cardiovascular Disease ISBN: 1607611856 ISBN-13(EAN): 9781607611851 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Covers aspects such as intracellular signaling, regulation of cell volume in the failing heart, the presence of an intracrine renin angiotensin system, and the influence of prorenin/renin, angiotensin II, angiotensin (1-7) and aldosterone. This book offers a review of the topics involving the renin angiotensin system and cardiovascular disease.
Описание: The primary aim of this book is to provide a topical and timely forum for the critical appraisal of an area of renin-angiotensin system (RAS) research that is expanding rapidly.
Автор: Frohlich Название: The Local Cardiac Renin-Angiotensin Aldosterone System ISBN: 1441905278 ISBN-13(EAN): 9781441905277 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans.
Описание: Highlighting the role local renin-angiotensin systems (RAS) play in pancreatic disease, this review presents the latest research advances in the field. These findings suggest both preventative measures and treatment for pancreatic disease.
Автор: Edward D. Frohlich; Richard N. Re Название: The Local Cardiac Renin-Angiotensin Aldosterone System ISBN: 1489981101 ISBN-13(EAN): 9781489981103 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans.
Автор: Sean E. Thatcher Название: The Renin-Angiotensin-Aldosterone System ISBN: 1493970283 ISBN-13(EAN): 9781493970285 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Discussing protocols in measuring components in the renin-angiotensin-aldosterone system (RAAS), this book also looks at methods to assess angiotensin peptides and the influence of RAAS components on mammalian diseases. In the Methods in Molecular Biology series, it lists the necessary materials in step-by-step, reproducible laboratory protocols.
Описание: The special issue of Molecular and Cellular Biochemistry focuses on `Control of Gene Expression by Catecholamines and the Renin-Angiotensin System` in health and disease. This focused issue is organized into chapters concentrating on catecholamines, angiotensin II, and the interaction between catecholamines and angiotensin II.
Автор: D. Ganten; M.P. Printz; M.I. Phillips; B.A. Sch?lk Название: The Renin Angiotensin System in the Brain ISBN: 3642464580 ISBN-13(EAN): 9783642464584 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The first publications on the presence of renin, angiotensino- gen and angiotensin-like material in brain tissue appeared about ten years ago. This coincided with the discovery of new biological actions of angiotensin in the brain and with the reinvestigation of already known central angiotensin effects. The possibility that angiotensin could be generated within the brain itself had therefore exciting implications. With the recent popularity of brain neuropeptides, interest in this area is even increasing. The discovery of renin-like activity as well as angiotensino- gen and angiotensin in the brain has led, admittedly by inductive inference, to the hypothesis of the existence of a complete endogenous renin-angiotensin system in the brain.1 For several years there was ardent discussion whether such a renin angiotensin system existed in the brain or not. Inductive inference always contains "an irrational element or a creative intuition".2In view of the biological relevance of a brain angiotensin system, deductive testing of the hypothesis was a worthwhile scientific project taken up by a number of investigators As a matter of principle it is not given to science, to reach either truth or falsity, scientific statements can only attain contmous degrees of probability whose unat- tamable upper and lower limits are truth or falsity. However, several of the early singular statements and results turned out to be reproducible and acceptable. The theory has thus so far passed its test and we have found no reason to discard it.
Автор: Hideshi Kobayashi; Yoshio Takei Название: The Renin-Angiotensin System ISBN: 3642647251 ISBN-13(EAN): 9783642647253 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The renin-angiotensin system and the mechanisms regulating this system developed during the adaptive evolution of verte- brates, along with many other systems involved in the in- tegrated survival of the organism.
Описание: Preface... Table of Contents... Contributing Authors...
1. A Brief Introduction into the Renin-Angiotensin-Aldosterone System: New and Old Techniques Sean E. Thatcher
2. A Color Segmentation Based Method to Quantify Atherosclerotic Lesion Compositions with Immunostaining Congqing Wu, Alan Daugherty, and Hong Lu 3. Assessment of Protein Carbonylation and Protein Tyrosine Phosphatase (PTP) Oxidation in Vascular Smooth Muscle Cells (VSMCs) using Immunoblotting Approaches Sofia Tsiropoulou and Rhian M. Touyz 4. Methods for Studying the Role of RAAS in the Modulation of Vascular Repair-Relevant Functions of Stem/Progenitor Cells Yagna P.R. Jarajapu 5. Use of a Fluorescent Substrate to Measure ACE2 Activity in the Mouse Abdominal Aorta Yu Wang, Lisa A. Cassis, and Sean E. Thatcher 6. Measuring Blood Pressure using a Non-Invasive Tail Cuff Method in Mice Yu Wang, Sean E. Thatcher, and Lisa A. Cassis 7. Blood Pressure Monitoring using Radio Telemetry Method in Mice Yu Wang, Sean E. Thatcher, and Lisa A. Cassis 8. Characterization and Functional Phenotyping of Renal Immune Cells via Flow Cytometry Nathan P. Rudemiller and Steven D. Crowley 9. Assessment of the Renin-Angiotensin System in Cellular Organelle: New Arenas for Study in the Mitochondria Bryan A. Wilson and Mark C. Chappell 10. Comprehensive Assessments of Energy Balance in Mice Justin L. Grobe 11. In Vitro Assays to Determine Smooth Muscle Cell Hypertrophy, Protein Content, and Fibrosis Katherine J. Elliott and Satoru Eguchi 12. A New Mouse Model for Introduction of Aortic Aneurysm by Implantation of Deoxycorticosterone Acetate Pellets or Aldosterone Infusion in the Presence of High Salt Shu Liu, Ming C. Gong, and Zhenheng Guo 13. Fluorescence-Based Binding Assay for Screening Ligands of Angiotensin Receptors Maiia E. Bragina, Nikolaos Stergiopulos, and Rodrigo A. Fraga-Silva 14. A Primer to Angiotensin Peptide Isolation, Stability, and Analysis by Nano-Liquid Chromatography with Mass Detection Mariola Olkowicz, Stefan Chlopicki, and Ryszard T. Smolenski 15. Analysis of Angiotensin Metabolism in the Kidney using Mass Spectrometry Nadja Grobe and Khalid M. Elased
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