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Molecular Biology of Human Cancers, Schulz


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Автор: Schulz   (Шульц)
Название:  Molecular Biology of Human Cancers
Перевод названия: Шульц: Молекулярная биология рака человека
ISBN: 9783031162855
Издательство: Springer
Классификация:

ISBN-10: 3031162854
Обложка/Формат: Hardback
Страницы: 542
Вес: 1.44 кг.
Дата издания: 01.03.2023
Язык: English
Издание: 2nd ed. 2023
Иллюстрации: 221 illustrations, color; 8 illustrations, black and white; xxi, 542 p. 229 illus., 221 illus. in color.
Размер: 254 x 178
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This textbook describes the most relevant molecular and biological processes in cancer, how they contribute to the development and progression of individual cancer types in humans, and how insights from molecular cancer research can be applied to improve cancer prevention, diagnostics and treatment. Part I of the textbook summarizes the current fundamental knowledge on the general properties of cancers, the causes of cancer, cancer genetics, genomics and epigenetics. Individual chapters address the functions of DNA damage and repair, oncogenes and tumor suppressors in carcinogenesis and discuss crucial mechanisms in cancer pathogenesis, such as apoptosis and replicative senescence, as well as the most relevant signal transduction pathways and regulatory networks. Part I concludes with a chapter on tumor invasion and metastasis and tumor immunology. In Part II, the most relevant mechanisms acting in individual human cancers (and subtypes) are described in more detail. This central part of the book contains individual sections on the most common human cancers highlighting the diversity in their genetic, molecular and cellular pathogenic mechanisms. How insights from molecular cancer research are translated into improvements in prevention, diagnosis, and treatment is outlined in Part III. This new edition has been extensively revised and includes in particular updated information on cancer genomics, epigenetics, viral carcinogenesis, cancer diagnostics and cancer therapy and a new chapter on lung cancers. Now more than ever, cancer research is an interdisciplinary endeavor that requires a basic knowledge of commonly used terms, facts and concepts. The aim of this book is to provide advanced students and practitioners in various disciplines with this foundation, bridging the gap between standard textbooks of molecular biology, pathology and oncology on the one hand and the specialized cancer literature on the other.
Дополнительное описание: Part I: Molecules, Genes, Cells and Mechanisms.- Chapter 1: An Introduction to Human Cancers.- Chapter 2: Cancer Genetics.- Chapter 3: DNA Damage and DNA Repair.- Chapter 4: Oncogenes.- Chapter 5: Tumor Suppressor Genes.- Chapter 6: Cancer Pathways.- Chap



Rare and uncommon gynecological cancers

Автор: Reed
Название: Rare and uncommon gynecological cancers
ISBN: 3642134912 ISBN-13(EAN): 9783642134913
Издательство: Springer
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Цена: 10760.00 р. 15372.00 -30%
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Описание: This book is intended as a reference manual that will provide the busy clinician with up-to-date information on the diagnosis and treatment of uncommon and rare gynecological cancers. While standard textbooks briefly cover these tumors, this is intended as a more comprehensive yet easy-to-use guide. After opening chapters on epidemiology, pathology, and diagnostic imaging, the full range of infrequently encountered gynecological cancers (ovarian, uterine, cervical, vaginal, and vulval) is presented and discussed with the aid of high-quality illustrations. In each case, detailed attention is paid to both differential diagnosis and current treatment options. The book has been written by an international panel of experts and is the first to gather all the uncommon and rare gynecological cancers together within one volume.

Treatment of advanced stage cancers

Автор: G.P. Talwar
Название: Treatment of advanced stage cancers
ISBN: 8173199329 ISBN-13(EAN): 9788173199325
Издательство: Alpha Science
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Цена: 6000.00 р. 8571.00 -30%
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Описание: Treatment of Advanced Stage Cancers describes newer options for treatment of advanced liver cancers; targeting of pancreatic cancers by silencing' RNA selective killing of tumour cells expressing hCG by a high affinity, high specificity antibody linked to curcumin.

Reviewed also are the next generation of recombinant immunotoxins; herbal formulations eliminating Human Papilloma Virus (HPV) in cervical cancer cells besides immune targeting of oncogenic proteins of HPV to achieve a therapeutic vaccine for carcinoma of cervix. The book discusses optimisation of antigens for anti-cancer vaccines and optimization of Dendritic cells and viral vectors for immunotherapy. Clinical and experimental results are reported on therapeutic benefits of cancers by Mycobacterium indicus pranii. (DCGI approved vaccine for leprosy marketed as Immuvac).

Other topics covered include treatment of Chronic Myeloid Leukemia, Radiation-Enhanced Immunotherapy of Advanced cancers, Neem leaf glycoproteins regulating immune response in cancer and biology of metastasis of Head and Neck cancers. A new blood test for early diagnosis of Epithelial Ovarian Cancers is also described. The opening chapter by the Nobel Laureate David Baltimore presents elegantly the role of Micro RNAs in chronic inflammatory response and cancers.

Apoptosis in Hormone-Dependent Cancers

Автор: Martin Tenniswood; Horst Michna
Название: Apoptosis in Hormone-Dependent Cancers
ISBN: 3662031248 ISBN-13(EAN): 9783662031247
Издательство: Springer
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Цена: 6986.00 р.
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Описание: It is now widely accepted that cells have the ability to initiate a program of gene-directed death, a process called "apoptosis" which may also be used as an innovative strategy for therapeutic intervention in cancer therapy.

The Genetic Basis of Haematological Cancers

Автор: Tosi
Название: The Genetic Basis of Haematological Cancers
ISBN: 0470979380 ISBN-13(EAN): 9780470979389
Издательство: Wiley
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Цена: 19158.00 р.
Наличие на складе: Поставка под заказ.

Clinical cases in pediatric skin cancers

Название: Clinical cases in pediatric skin cancers
ISBN: 3030936651 ISBN-13(EAN): 9783030936655
Издательство: Springer
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Цена: 11179.00 р.
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Описание: This book is a concise practical guide designed to facilitate the clinical decision-making process in the management of pediatric skin cancers. Dermatologists, oncologists and general pediatricians who offer primary care to children must be knowledgeable in identifying and managing dermatological cancers, and this title provides insightful reviews of a number of common and rare dermatologic cases. Clinical cases are a key component in modern medical education, assisting the trainee or recertifying clinician to work through unusual scenarios using best practice techniques. Pediatric dermatology is a particularly important discipline in this regard since it is a highly visual subject requiring the reader to describe often very subtle differences in the presentation of patients and define accurately the diagnostic and management criteria on which to base their clinical decision-making. Clinical Cases in Pediatric Skin Cancers concisely covers how to approach diagnosing and managing skin cancers in pediatric patients. Each chapter focuses on a particular case and emphasizes how to make an appropriate choice when deciding which diagnostic tool or management strategy would be most suitable. Potential complications are detailed and management tips provided to enable the reader to develop a deep understanding of how approach the care of these patients within their day-to-day clinical practice. This book therefore represents an ideal up-to-date resource for all practitioners who encounter these cases as part of their everyday practice.

Origin of Cancers

Автор: Shi-Ming Tu
Название: Origin of Cancers
ISBN: 1461426030 ISBN-13(EAN): 9781461426035
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Many prominent researchers have established the foundation for the theory of a stem-cell origin of cancer, and they`ve performed vital experiments to support its validity. This book illustrates how this theory may transform our current understanding of cancer.

Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics

Автор: Jianguo Tao; Eduardo Sotomayor
Название: Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics
ISBN: 9400795815 ISBN-13(EAN): 9789400795815
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book encompasses a decade of explosive growth in knowledge of the pathobiology of hematologic cancer, and offers the insight of experts from around the world on current treatment approaches and on future progress in malignant hematologic diseases.

The Biology and Prevention of Aerodigestive Tract Cancers

Автор: Guy R. Newell; Waun Ki Hong
Название: The Biology and Prevention of Aerodigestive Tract Cancers
ISBN: 1461365368 ISBN-13(EAN): 9781461365365
Издательство: Springer
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Цена: 6986.00 р.
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Описание: The papers contained in this volume were presented ati the Golden Jubilee Cancer Prevention Conference, "The Biology and Prevention of Aerodigestive Tract Cancers," sponsored by The University of Texas M. Aerodigestive tract cancers account for about 20% of newly diagnosed invasive cancers.

The Biology of Gastric Cancers

Автор: Timothy Wang; James Fox; Andy Giraud
Название: The Biology of Gastric Cancers
ISBN: 1441924051 ISBN-13(EAN): 9781441924056
Издательство: Springer
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Цена: 21661.00 р.
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Описание: This book is the first ever devoted to the basic biology of gastric cancer. Not only does it fully cover the history of clinical gastric cancer research, it also discusses cutting edge concepts in cancer stem cells, tumor microenvironment, chronic inflammation and genetic susceptibility.

Early Gastrointestinal Cancers

Автор: Florian Otto; Manfred P. Lutz
Название: Early Gastrointestinal Cancers
ISBN: 3642441610 ISBN-13(EAN): 9783642441615
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This Recent Results in Cancer Research volume contains the majority of the invited expert contributions from the First St. Gallen EORTC Gastrointestinal Cancer Conference, held on 22-24 March 2012 in St. Gallen, Switzerland. Written by some of the world’s leading experts in the field, the volume constitutes a comprehensive update on recent developments in the imaging, molecular biology, pathology, and multidisciplinary management of early cancer of the gastrointestinal tract. The latest recommendations regarding diagnosis and treatment are provided, and areas of consensus and controversy, identified. While the principal focus is on esophageal and gastric cancer, advances in the treatment of colorectal and pancreatic cancer are also discussed in some detail. This book will be of interest to every clinician involved in the care of patients with gastrointestinal malignancies.

Rare Hereditary Cancers

Автор: Gabriella Pichert; Chris Jacobs
Название: Rare Hereditary Cancers
ISBN: 3319299964 ISBN-13(EAN): 9783319299969
Издательство: Springer
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Цена: 19564.00 р.
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Описание:

This book approaches the differential diagnosis and management of rare, hereditary cancer syndromes from a practical angle, addressing the issues pertinent to each tumour type as encountered by health professionals in their day-to-day practice. This book enables readers to correctly identify patients with rare cancer syndromes who would benefit from genetic counselling and testing, and provides the necessary knowledge for appropriate patient management and advising at-risk family members. It begins by describing recent advances in genetic testing for cancer-predisposing genes. Leading experts from Europe and Australia then offer detailed, up-to-date guidance on the diagnosis and management of a wide range of hereditary cancers. The concluding chapter examines the wider issues that are raised by genetic testing for rare cancer syndromes for patients, families and health professionals. This book is an invaluable source of information for all specialists involved in the care of such patients and their families.
Computational Intelligence in Oncology

Автор: Raza
Название: Computational Intelligence in Oncology
ISBN: 9811692238 ISBN-13(EAN): 9789811692239
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book encapsulates recent applications of CI methods in the field of computational oncology, especially cancer diagnosis, prognosis, and its optimized therapeutics. The cancer has been known as a heterogeneous disease categorized in several different subtypes. According to WHO’s recent report, cancer is a leading cause of death worldwide, accounting for over 10 million deaths in the year 2020. Therefore, its early diagnosis, prognosis, and classification to a subtype have become necessary as it facilitates the subsequent clinical management and therapeutics plan. Computational intelligence (CI) methods, including artificial neural networks (ANNs), fuzzy logic, evolutionary computations, various machine learning and deep learning, and nature-inspired algorithms, have been widely utilized in various aspects of oncology research, viz. diagnosis, prognosis, therapeutics, and optimized clinical management. Appreciable progress has been made toward the understanding the hallmarks of cancer development, progression, and its effective therapeutics. However, notwithstanding the extrinsic and intrinsic factors which lead to drastic increment in incidence cases, the detection, diagnosis, prognosis, and therapeutics remain an apex challenge for the medical fraternity. With the advent in CI-based approaches, including nature-inspired techniques, and availability of clinical data from various high-throughput experiments, medical consultants, researchers, and oncologists have seen a hope to devise and employ CI in various aspects of oncology. The main aim of the book is to occupy state-of-the-art applications of CI methods which have been derived from core computer sciences to back medical oncology. This edited book covers artificial neural networks, fuzzy logic and fuzzy inference systems, evolutionary algorithms, various nature-inspired algorithms, and hybrid intelligent systems which are widely appreciated for the diagnosis, prognosis, and optimization of therapeutics of various cancers. Besides, this book also covers multi-omics exploration, gene expression analysis, gene signature identification of cancers, genomic characterization of tumors, anti-cancer drug design and discovery, drug response prediction by means of CI, and applications of IoT, IoMT, and blockchain technology in cancer research.


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