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Real-World Evidence in Medical Product Development, He


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Цена: 16070.00р.
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При оформлении заказа до: 2025-07-28
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Автор: He
Название:  Real-World Evidence in Medical Product Development
ISBN: 9783031263279
Издательство: Springer
Классификация:

ISBN-10: 3031263278
Обложка/Формат: Hardback
Вес: 0.00 кг.
Язык: English
Иллюстрации: VIII, 292 p. 45 illus., 38 illus. in color.
Читательская аудитория: Professionals
Основная тема: Statistics
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book provides state-of-art statistical methodologies, practical considerations from regulators and sponsors, logistics, and real use cases for practitioners for the uptake of RWE/D. Randomized clinical trials have been the gold standard for the evaluation of efficacy and safety of medical products. However, the cost, duration, practicality, and limited generalizability have incentivized many to look for alternative ways to optimize drug development. This book provides a comprehensive list of topics together to include all aspects with the uptake of RWE/D, including, but not limited to, applications in regulatory and non-regulatory settings, causal inference methodologies, organization and infrastructure considerations, logistic challenges, and practical use cases.
Дополнительное описание: Preface.- Part I. Real-World Data and Evidence to Accelerate Medical Product Development.- The need for real world data/evidence in clinical development and life cycle management, and future directions.- Overview of current RWE/RWD landscape.- Key conside



Computer Age Statistical Inference, Student Edition

Автор: Bradley Efron , Trevor Hastie
Название: Computer Age Statistical Inference, Student Edition
ISBN: 1108823416 ISBN-13(EAN): 9781108823418
Издательство: Cambridge Academ
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Цена: 5069.00 р.
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Описание: Computing power has revolutionized the theory and practice of statistical inference. Now in paperback, and fortified with 130 class-tested exercises, this book explains modern statistical thinking from classical theories to state-of-the-art prediction algorithms. Anyone who applies statistical methods to data will value this landmark text.

Real-World Evidence in Drug Development and Evaluation

Название: Real-World Evidence in Drug Development and Evaluation
ISBN: 036702621X ISBN-13(EAN): 9780367026219
Издательство: Taylor&Francis
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Цена: 19906.00 р.
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Описание: This book concerns use of real world data (RWD) and real world evidence (RWE) to aid drug development across product cycle. RWD are healthcare data that are collected outside the constraints of conventual controlled randomized trials (CRTs); whereas RWE is the knowledge derived from aggregation and analysis of RWD.

Real-world evidence in drug development and evaluation

Название: Real-world evidence in drug development and evaluation
ISBN: 0367637014 ISBN-13(EAN): 9780367637019
Издательство: Taylor&Francis
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Цена: 6889.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book concerns use of real world data (RWD) and real world evidence (RWE) to aid drug development across product cycle. RWD are healthcare data that are collected outside the constraints of conventual controlled randomized trials (CRTs); whereas RWE is the knowledge derived from aggregation and analysis of RWD.

Real-world evidence in a patient-centric digital era

Название: Real-world evidence in a patient-centric digital era
ISBN: 036786181X ISBN-13(EAN): 9780367861810
Издательство: Taylor&Francis
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Цена: 15310.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book will be a vital reference for medical researchers, health technology innovators, data scientists, epidemiologists, population health analysts, health economists, outcomes researchers, as well as policymakers and analysts in the healthcare industry.

A Disequilibrium Model of Real and Financial Accumulation in an Open Economy

Автор: Giancarlo Gandolfo; Pietro C. Padoan
Название: A Disequilibrium Model of Real and Financial Accumulation in an Open Economy
ISBN: 3540138897 ISBN-13(EAN): 9783540138891
Издательство: Springer
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Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Evidence Synthesis using Individual Participant Da ta

Автор: Riley
Название: Evidence Synthesis using Individual Participant Da ta
ISBN: 1119333725 ISBN-13(EAN): 9781119333722
Издательство: Wiley
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Цена: 10446.00 р.
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Описание:

Individual Participant Data Meta-Analysis: A Handbook for Healthcare Research provides a comprehensive introduction to the fundamental principles and methods that healthcare researchers need when considering, conducting or using individual participant data (IPD) meta-analysis projects. Written and edited by researchers with substantial experience in the field, the book details key concepts and practical guidance for each stage of an IPD meta-analysis project, alongside illustrated examples and summary learning points.

Split into five parts, the book chapters take the reader through the journey from initiating and planning IPD projects to obtaining, checking, and meta-analysing IPD, and appraising and reporting findings. The book initially focuses on the synthesis of IPD from randomised trials to evaluate treatment effects, including the evaluation of participant-level effect modifiers (treatment-covariate interactions). Detailed extension is then made to specialist topics such as diagnostic test accuracy, prognostic factors, risk prediction models, and advanced statistical topics such as multivariate and network meta-analysis, power calculations, and missing data.

Intended for a broad audience, the book will enable the reader to:

  • Understand the advantages of the IPD approach and decide when it is needed over a conventional systematic review
  • Recognise the scope, resources and challenges of IPD meta-analysis projects
  • Appreciate the importance of a multi-disciplinary project team and close collaboration with the original study investigators
  • Understand how to obtain, check, manage and harmonise IPD from multiple studies
  • Examine risk of bias (quality) of IPD and minimise potential biases throughout the project
  • Understand fundamental statistical methods for IPD meta-analysis, including two-stage and one-stage approaches (and their differences), and statistical software to implement them
  • Clearly report and disseminate IPD meta-analyses to inform policy, practice and future research
  • Critically appraise existing IPD meta-analysis projects
  • Address specialist topics such as effect modification, multiple correlated outcomes, multiple treatment comparisons, non-linear relationships, test accuracy at multiple thresholds, multiple imputation, and developing and validating clinical prediction models
Detailed examples and case studies are provided throughout.
Converting Data into Evidence

Автор: Alfred DeMaris; Steven H. Selman
Название: Converting Data into Evidence
ISBN: 1461477913 ISBN-13(EAN): 9781461477914
Издательство: Springer
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Цена: 6986.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book provides an introduction to key statistical techniques medical practitioners encounter throughout their careers. It utilizes real data sets from recent clinical trials and observational studies in urology to illustrate data analysis techniques.

Medical Product Safety Evaluation

Автор: Chen, Jie
Название: Medical Product Safety Evaluation
ISBN: 036757117X ISBN-13(EAN): 9780367571177
Издательство: Taylor&Francis
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Цена: 7348.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

The Analysis of Biological Data

Автор: Michael C. Whitlock, Dolph Schluter
Название: The Analysis of Biological Data
ISBN: 1319325343 ISBN-13(EAN): 9781319325343
Издательство: Macmillan Learning
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Цена: 13858.00 р.
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Описание: The evolution of a classicThe new 12th edition of Introduction to Genetic Analysis takes this cornerstone textbook to the next level.

Achieving product reliability :

Автор: Doganaksoy, Necip,
Название: Achieving product reliability :
ISBN: 1032019964 ISBN-13(EAN): 9781032019963
Издательство: Taylor&Francis
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Цена: 13779.00 р.
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Описание: Readers who are interested in learning how statistics is used to solve real-life reliability problems. Real-life examples and case studies to illustrate applications of statistics with heavy reliance of data and analysis graphs to provide a general appreciation of the subject. Only a rudimentary of some basic statistical concepts is assumed.

Meta analysis

Автор: Kulinskaya, E Morgenthaler, Stephan Staudte, Rober
Название: Meta analysis
ISBN: 0470028645 ISBN-13(EAN): 9780470028643
Издательство: Wiley
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Цена: 10130.00 р.
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Описание: Meta Analysis: A Guide to Calibrating and Combining Statistical Evidence acts as a source of basic methods for scientists wanting to combine evidence from different experiments. The authors aim to promote a deeper understanding of the notion of statistical evidence. The book is comprised of two parts - The Handbook, and The Theory.

Measuring Uncertainty within the Theory of Evidence

Автор: Simona Salicone; Marco Prioli
Название: Measuring Uncertainty within the Theory of Evidence
ISBN: 303008924X ISBN-13(EAN): 9783030089245
Издательство: Springer
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Цена: 15372.00 р.
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Описание:

This monograph considers the evaluation and expression of measurement uncertainty within the mathematical framework of the Theory of Evidence. With a new perspective on the metrology science, the text paves the way for innovative applications in a wide range of areas. Building on Simona Salicone’s Measurement Uncertainty: An Approach via the Mathematical Theory of Evidence, the material covers further developments of the Random Fuzzy Variable (RFV) approach to uncertainty and provides a more robust mathematical and metrological background to the combination of measurement results that leads to a more effective RFV combination method.
While the first part of the book introduces measurement uncertainty, the Theory of Evidence, and fuzzy sets, the following parts bring together these concepts and derive an effective methodology for the evaluation and expression of measurement uncertainty. A supplementary downloadable program allows the readers to interact with the proposed approach by generating and combining RFVs through custom measurement functions. With numerous examples of applications, this book provides a comprehensive treatment of the RFV approach to uncertainty that is suitable for any graduate student or researcher with interests in the measurement field.

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