Описание: Intends to showcase the important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. This title covers ribosomally-synthesised and Non-ribosomally-synthesised peptides.
Описание: Intends to showcase important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. This title covers biosynthesis of Polyketides, Tarpenoids, Aminocoumarins and Crabohydrates.
Автор: Walsh Christopher T., Tang Yi Название: Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery ISBN: 1788010760 ISBN-13(EAN): 9781788010764 Издательство: Marston Book Services Рейтинг: Цена: 17818.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.
Автор: Bradley Evans Название: Nonribosomal Peptide and Polyketide Biosynthesis ISBN: 1493933736 ISBN-13(EAN): 9781493933730 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This volume presents an overview of nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) structure and function. It then continues with methods for the analysis of these pathways including conventional enzymological assays, contemporary mass spectrometric analysis techniques, specialized molecular biological approaches applicable to NRPSs and PKSs, and small molecule analysis tools tailored to this very special class of natural products, and concludes by examining bioinformatics tools for the analysis of these enzymes, pathways, and molecules. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Nonribosomal Peptide and Polyketide Biosynthesis: Methods and Protocols serves as a valuable reference for those experienced in studying NRPS and PKS enzymes, pathways, and natural products as well as a gateway for those just entering the field.
Описание: Part of Methods in Enzymology series, this title covers Natural product biosynthesis by microorganisms and plants, it has chapters on such topics as Kinetics of plant sesquiterpene synthases, and plant Type III polyketide synthases.
Описание: Covers Natural product biosynthesis by microorganisms and plants. This title includes chapters on such topics as metabolic pathways in Aspergillus oryzae, heterologous gene clusters and cyanobacteria as a source of natural products.
Автор: Mulla Sikandar I., Bharagava R. N. Название: Enzymes for Pollutant Degradation ISBN: 9811645736 ISBN-13(EAN): 9789811645730 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1 Oxidoreductases for removal of environmental pollutants.- 2 Synthesis of industrial enzymes from lignocellulosic fractions.- 3 Pleurotus-derived laccases, immobilization, and bioremediation applications.- 4 Microbial lipases for polyester degradation.- 5 Application of Microbial Biofilms in Biocatalysis and Biodegradation.- 6 Pyrethroid-degrading microorganisms and their potential application for the bioremediation of contaminated environments.- 7 Bacterial Biodegradation of Phenolic Hydrocarbons.- 8 Biosorption of Industrial wastewater by microalgae.- 9 Plastic degradation and utilization by microbes: Challenges and scope.- 10 Marine Microorganisms: From pollutant degradation to added-value products.- 11 Biodegradation of pesticides used in the agriculture by soil microorganisms.- 12 Probiotic enzymes in biodegradation and value-added products.- 13 Current state, challenges and perspectives on microbial degradation of dioxine and furan.- 14 The Management of Crude Oil Spill by Bioremediation Technique.- 15 Bacterial Pigments- an Untapped Colorful Microbial World.- 16 Bioinoculants for rapid production of vermicompost.- 17 Microbial-mediated mechanism to improve rock phosphate solubilization and its agronomic implications.
Автор: Claudiu T. Supuran; Clemente Capasso Название: Zinc Enzyme Inhibitors ISBN: 3319461117 ISBN-13(EAN): 9783319461113 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Описание: Moleskine`s Classic Backpack, in black, a discreet and iconic notebook-inspired piece with space for everything you need as you navigate the city unfolding before you. Made from water-repellent PU leather with adjustable straps with sliding buckles. The backpack also includes two side pockets to keep essentials within easy reach and quality metal YKK zip pullers. On the inside, there is grey lining, a my Moleskine` notes pocket to store ideas, a padded laptop and tablet pocket (fits devices up to 15`), a secure zip pocket and an organiser with two pen holders and business card holder.
Автор: Supuran Claudiu T., Capasso Clemente Название: Zinc Enzyme Inhibitors: Enzymes from Microorganisms ISBN: 3319834444 ISBN-13(EAN): 9783319834443 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An Elusive Task: A Clinically Useful Inhibitor of Metallo-β-Lactamases.- Inhibitors of Histidinol Dehydrogenase.- Botulinum Neurotoxin, Tetanus Toxin, and Anthrax Lethal Factor Countermeasures.- Inhibition and Activity Regulation of Bacterial Collagenases.- Fungal Carbonic Anhydrases and Their Inhibition.- Protozoan Carbonic Anhydrases.- Bacterial Carbonic Anhydrases.
Описание: This open access book offers a comprehensive overview of the role and potential of microorganisms in the degradation and preservation of cultural materials (e.g.
Автор: Paley, Elena L. Название: Protein biosynthesis interference in disease ISBN: 0128234857 ISBN-13(EAN): 9780128234853 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Поставка под заказ.
Описание: Letter Jam is a 2-6 player cooperative word game where players assist each other in composing meaningful words from letters around the table. The trick is holding the letter card so that it`s only visible to other players and not to you.At the start of the game, each player receives a set of face-down letter cards that can be arranged to form an existing word. The setup can be prepared by using a special card scanning app, or by players selecting words for each other. Each player then puts their first card in their stand facing the other players without looking at it, and the game begins.The game is played in turns. Each turn, players simultaneously search other players` letters to see what words they can spell out (telling the others the length of the word they can make up). The player who offers the longest word can then be chosen as the clue giver.The clue giver spells out their clue by putting numbered tokens in front of the other players. Number one goes to the player whose letter comes first in the clue, number two to the second letter etc. They can always use a wild card which can be any letter, but they cannot tell others which letter it represents.Each player with a numbered token (or tokens) in front of them then tries to figure out what their letter is. If they do, they place the card face down before revealing the next letter. At the end of the game, players can then rearrange the cards to try to form an existing word. All players then reveal their cards to see if they were successful or not. The more players who have an existing word in front of them, the bigger their common success.
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